The novel inflammatory biomarker GlycA and triglyceride-rich lipoproteins are associated with the presence of subclinical myocardial dysfunction in subjects with type 1 diabetes mellitus

Carlos Puig-Jové, Josep Julve, Esmeralda Castelblanco, M Teresa Julián, Núria Amigó, Henrik U Andersen, Tarunveer S Ahluwalia, Peter Rossing, Dídac Mauricio, Magnus T Jensen & Núria Alonso
Abstract Background Subjects with Type 1 diabetes mellitus (T1DM) have an increased incidence of heart failure (HF). Several pathophysiological mechanisms have been involved in its development. The aim of this study was to analyze the potential contribution of the advanced lipoprotein profile and plasma glycosylation (GlycA) to the presence of subclinical myocardial dysfunction in subjects with T1DM. Methods We included subjects from a Danish cohort of T1DM subjects (Thousand & 1 study) with either diastolic...
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