HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread

Tongcui Ma, Xiaoyu Luo, Ashley George, Gourab Mukherjee, Nandini Sen, Trimble Spitzer, Linda Giudice, Warner Greene & Nadia Roan
The female reproductive tract (FRT) is the most common site of infection during HIV transmission to women, but viral remodeling complicates characterization of cells targeted for infection. Here, we report extensive phenotypic analyses of HIV-infected endometrial cells by CyTOF, and use a "nearest neighbor" bioinformatics approach to trace cells to their original pre-infection phenotypes. Like in blood, HIV preferentially targets memory CD4+ T cells in the endometrium, but these cells exhibit unique phenotypes and sustain...
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These counts follow the COUNTER Code of Practice, meaning that Internet robots and repeats within a certain time frame are excluded.
What does this mean?