Gut Microbiota from Multiple Sclerosis patients triggers spontaneous autoimmune encephalomyelitis in mice --16S data--

Hartmut Wekerle, Kerstin Berer, Lisa Ann Gerdes, Egle Cekanaviciute, Sherman Jia, Liang Xiao, Zhongkui Xia, Chuan Liu, Luisa Klotz, Uta Stauffer, Sergio Baranzini, Tania Kümpfel, Reinhard Hohlfeld & Gurumoorthy Krishnamoorthy
The commensal microbiota has emerged as a key factor influencing human health and has been associated with several diseases, including those of the central nervous system (CNS). To investigate the role of the microbiome in multiple sclerosis (MS), a complex autoimmune disorder shaped by a multitude of genetic and environmental factors, we recruited a cohort of 34 monozygotic twin pairs discordant for MS, and compared their gut microbial composition by 16S ribosomal RNA sequencing of...
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