Targeting Flavor Deglycosylation Improves Formulation of Whole Celery-Based Apigenin Rich Food

Zach Heeringa, Meenakshi Sudhakaran, Alison M. Gjidoda & Andrea I. Doseff
Flavone apigenin is a plant bioactive compound abundantly found in human diets. Apigenin has antioxidant, anti-inflammatory and anti-carcinogenic activities, thereby presenting promising yet unexploited prospects for the prevention and treatment of various inflammatory diseases. Apigenin, like other flavones, naturally occursin plants in its glycoside form. However, apigenin glycosides are less absorbed compared to their aglycone counterparts leading to diminished antiinflammatory and anti-cancer activities in in vitro and in vivo models. Additionally, apigenin aglycones have poor...
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