Applying phase plane analysis to cerebrovascular autoregulation and patient outcome following brain injury

Courtney Erin Semkewyc
Cerebrovascular autoregulation (AR) is an important mechanism within the brain that aims to maintain adequate blood flow to all lobes thus promoting proper brain function. Brain injuries due to a traumatic (TBI) or non-TBI event can damage this internal feedback mechanism leading to an impaired response that can lead to secondary injury in the form of swelling or ischemia. This impaired response is reflected in the intracranial pressure (ICP) waveform in the form of varying...
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