Pairwise antagonism assay of clinical Acinetobacter isolates

Amy M Summers, Rae A Heitkamp, Sylvia Cheng & Benjamin C Kirkup
Many bacteria antagonize each other in nature; laboratory evidence of these interactions dates from 1925 (Gratia). However, antagonism assays are typically performed between a small number of 'sensitive' strains screening a range of potential 'killers' in the hunt for natural antibiotics, or a single 'killer' against a broad range of 'pathogens.' By contrast, several recent studies have performed pairwise assays across a range of organisms; including marine Vibrio (Cordero et al 2012) and fresh water...