An Investigation of Synaptic Dysfunction in Alzheimer’s Disease - Chapter 3 - Matlab Scripts

Rosemary J Jackson
Alzheimer’s disease (AD) is characterized by the presence of aggregates of amyloid beta (Aβ) in senile plaques and tau in neurofibrillary tangles, as well as marked neuron and synapse loss. Of these pathological changes, synapse loss correlates most strongly with cognitive decline. Understanding the contributions of different risk factors, toxic proteins, and protein networks to synaptic dysfunction is essential to understanding and one day curing this disease. Oligomeric species of Aβ are implicated in synapse...
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