Reconstruction of B cell lineages

Barbera Van Schaik, Marieke E Doorenspleet, Paul L Klarenbeek, Rebecca EE Esveldt, Niek De Vries & Antoine HC Van Kampen
T and B cells of the adaptive immune system are highly specialized cells that orchestrate a targeted attack against pathogens. Variability in the T and B cell repertoire is introduced by somatic rearrangement of the receptor genes to recognize many antigens. In addition, B cells can increase their specificity by mutating their receptor to improve recognition of the antigen. Understanding this process might greatly enhance our understanding of immune responses in health and disease.

We will...
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.