Evaluation of the application of the European guidelines for diagnosis and clinical care of amyotrophic lateral sclerosis

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The diagnosis and management of patients in French ALS referral centers are in agreement with most EAN/EFNS guidelines.
- The most satisfactory aspects are: methods for diagnosis, breaking the news, multidisciplinary and regular management, neuroprotective treatment, symptomatic treatment, management of respiratory involvement and nutritional aspects.
- Conversely, palliative care appears as belated in terms of discussion and involvement of palliative care team.
- Even in a context of standardized care covered by guidelines, center effect has been identified...
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