Hypersensitivity reactions with an overview on anaphylaxis

Hypersensitivity Reaction: A state of altered reactivity in which the body reacts with an exaggerated immune response to a foreign agent. These reactions may be damaging, uncomfortable, or occasionally fatal. Coombs and Gell classified hypersensitivity into 4 types.

Anaphylaxis: Ana (without), phylaxis (protection). Acute multi-systemic allergic reaction involving the skin, airway, vascular system, and GI. Anaphylaxis is defined as a serious allergic or hypersensitivity reaction (type 1) that is rapid in onset and may cause death.
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