Rodent models of obesity.

Michael Doulberis, Apostolis Papaefthymiou, Stergios A Polyzos, Panagiotis Katsinelos, Nikolaos Grigoriadis, David S. Srivastava & Jannis Kountouras
Obese or overweight people exceed one-third of the global population and obesity along with diabetes mellitus consist basic components of metabolic syndrome, both of which are known cardio-cerebrovascular risk factors with detrimental consequences. These data signify the pandemic character of obesity and the necessity for effective treatments. Substantial advances have been accomplished in preclinical research of obesity by using animal models, which mimic the human disease. In particular, rodent models have been widely used for...
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