New-to-Nature Selective C-H Alkylation Using Engineered Carbene Transferases

Juner Zhang
Synthetic methods to selectively convert C–H bonds, a prevalent motif in organic molecules, into functionalities can significantly accelerate the syntheses and derivatization of molecules. In the past decade, many enzymatic catalysts have emerged as greener, more selective, and more versatile alternatives to small-molecule catalysts for selective C–H functionalization reactions. In nature, enzymes only catalyze a limited set of C–H functionalization reactions that are useful for chemical synthesis, as the overwhelming majority of known C–H functionalization...
This data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.