The Relationship Between Parkinson's Disease and Essential Tremor: Review of Clinical, Epidemiologic, Genetic, Neuroimaging and Neuropathological Data, and Data on the Presence of Cardinal Signs of Parkinsonism in Essential Tremor

Félix Javier Jiménez-Jiménez, Hortensia Alonso-Navarro, Elena García-Martín & José A.G. Agúndez
Background: The possible relationship between essential tremor (ET) and Parkinson’s disease (PD) remains controversial since the first description of PD. However, there is increasing evidence suggesting the overlap between these two disorders. The aim of this review is to examine the relationship between PD and ET, focusing on clinical, epidemiologic, genetic, neuroimaging and neuropathological data, and the presence of cardinal symptoms of parkinsonism in ET. Methods: We conducted a PubMed search from 1966 until November...
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