13,778,103 Works

Additional file 3: of Historical biogeography reveals new independent evolutionary lineages in the Pantosteus plebeius-nebuliferus species-group (Actinopterygii: Catostomidae)

Diushi Corona-Santiago, Omar Domínguez-Domínguez, Llanet Tovar-Mora, José Ramón Pardos-Blas, Yvonne Herrerías-Diego, Rodolfo Pérez-Rodríguez & Ignacio Doadrio
Phylogenetic tree (Bayesian Inference/Maximum Likelihood) based on nuclear gene GHI for the Pantosteus plebeius-nebuliferus species-group. (EPS 1151 kb)

Effectiveness and cost-effectiveness of a loyalty scheme for physical activity behaviour change maintenance: results from a cluster randomised controlled trial

Ruth Hunter, Jennifer Murray, Aisling Gough, Jianjun Tang, Christopher Patterson, David French, Emma McIntosh, Yiqiao Xin & Frank Kee
Abstract Background We evaluated the effectiveness and cost-effectiveness of a loyalty scheme based intervention involving rewards for increasing physical activity in public sector employees. Methods A cluster randomised wait-list controlled trial in public sector organisations in Northern Ireland. We randomly assigned clusters (1:1) using a computer generated random sequence. Researchers were masked to allocation, but participants were not. Employees aged 18–65 years with no self-reported medical contraindications to physical activity were included. The Physical Activity Loyalty...

Additional file 1: of Historical biogeography reveals new independent evolutionary lineages in the Pantosteus plebeius-nebuliferus species-group (Actinopterygii: Catostomidae)

Diushi Corona-Santiago, Omar Domínguez-Domínguez, Llanet Tovar-Mora, José Ramón Pardos-Blas, Yvonne Herrerías-Diego, Rodolfo Pérez-Rodríguez & Ignacio Doadrio
Evolutionary substitution model and estimated parameters for cytb and GHI by Akaike Information Criterion. (DOC 35 kb)

MOESM7 of The Plasmodium falciparum cytoplasmic translation apparatus: a promising therapeutic target not yet exploited by clinically approved anti-malarials

Christine Sheridan, Valentina Garcia, Vida Ahyong & Joseph DeRisi
Additional file 7. Mefloquine solubility assay. Dose-dependent inhibition of P. falciparum in vivo growth by mefloquine in PfIVT extract post-PfIVT reaction (Mefloquine IVT Extract), mefloquine alone (Mefloquine No Extract), or DMSO control in PfIVT extract post-PfIVT reaction (Extract + DMSO).

MOESM6 of The Plasmodium falciparum cytoplasmic translation apparatus: a promising therapeutic target not yet exploited by clinically approved anti-malarials

Christine Sheridan, Valentina Garcia, Vida Ahyong & Joseph DeRisi
Additional file 6. Dose-dependent inhibition of S35 incorporation and PfIVT assays by cycloheximide. Dose-dependent inhibition of S35 incorporation (blue bars) and PfIVT assays (red bars) by the translation inhibitor cycloheximide, tested up to 1000-fold (**) the EC50 calculated in P. falciparum growth inhibition assay.

Additional file 2: of Historical biogeography reveals new independent evolutionary lineages in the Pantosteus plebeius-nebuliferus species-group (Actinopterygii: Catostomidae)

Diushi Corona-Santiago, Omar Domínguez-Domínguez, Llanet Tovar-Mora, José Ramón Pardos-Blas, Yvonne Herrerías-Diego, Rodolfo Pérez-Rodríguez & Ignacio Doadrio
Phylogenetic tree (Bayesian Inference/Maximum Likelihood) based on mitochondrial gene cytb for the Pantosteus plebeius-nebuliferus species-group. (EPS 1046 kb)

Additional file 1: of Colony-stimulating factor 1 receptor inhibition prevents disruption of the blood-retina barrier during chronic inflammation

Despina Kokona, Andreas Ebneter, Pascal Escher & Martin Zinkernagel
Figure S1 Aquaporin 4 immunoreactivity in the retina of control and LPS-challenged mice. (ZIP 671 kb)

MOESM5 of The Plasmodium falciparum cytoplasmic translation apparatus: a promising therapeutic target not yet exploited by clinically approved anti-malarials

Christine Sheridan, Valentina Garcia, Vida Ahyong & Joseph DeRisi
Additional file 5. Method for PfIVT assay: step-by-step protocol.

Additional file 1: of Topical anti-inflammatory and anti-oxidative effects of porcine placenta extracts on 2,4-dinitrochlorobenzene-induced contact dermatitis

Jae Hyeok Heo, Yoonki Heo, Hee Jung Lee, Minjee Kim & Ha Youn Shin
Figure S1. PPE dramatically alleviated epidermal thickening of DNCB-induced inflammatory lesions in vivo; Figure S2. IgE and IgG levels; Figure S3. Nuclear staining in HaCaT cells; Figure S4. PPE prevents the oxidative degradation of HA by inhibiting hyaluronidase activity; Supplementary methods: Detection of ROS-induced HA degradation in vitro and HA zymography. (DOCX 1687 kb)

Additional file 1: of Topical anti-inflammatory and anti-oxidative effects of porcine placenta extracts on 2,4-dinitrochlorobenzene-induced contact dermatitis

Jae Hyeok Heo, Yoonki Heo, Hee Jung Lee, Minjee Kim & Ha Youn Shin
Figure S1. PPE dramatically alleviated epidermal thickening of DNCB-induced inflammatory lesions in vivo; Figure S2. IgE and IgG levels; Figure S3. Nuclear staining in HaCaT cells; Figure S4. PPE prevents the oxidative degradation of HA by inhibiting hyaluronidase activity; Supplementary methods: Detection of ROS-induced HA degradation in vitro and HA zymography. (DOCX 1687 kb)

MOESM6 of The Plasmodium falciparum cytoplasmic translation apparatus: a promising therapeutic target not yet exploited by clinically approved anti-malarials

Christine Sheridan, Valentina Garcia, Vida Ahyong & Joseph DeRisi
Additional file 6. Dose-dependent inhibition of S35 incorporation and PfIVT assays by cycloheximide. Dose-dependent inhibition of S35 incorporation (blue bars) and PfIVT assays (red bars) by the translation inhibitor cycloheximide, tested up to 1000-fold (**) the EC50 calculated in P. falciparum growth inhibition assay.

Additional file 1: of Colony-stimulating factor 1 receptor inhibition prevents disruption of the blood-retina barrier during chronic inflammation

Despina Kokona, Andreas Ebneter, Pascal Escher & Martin Zinkernagel
Figure S1 Aquaporin 4 immunoreactivity in the retina of control and LPS-challenged mice. (ZIP 671 kb)

Perioperative administration of buffered versus non-buffered crystalloid intravenous fluid to improve outcomes following adult surgical procedures: a Cochrane systematic review

Peter Odor, Sohail Bampoe, Ahilanandan Dushianthan, Elliott Bennett-Guerrero, Suzie Cro, Tong Gan, Michael Grocott, Michael James, Michael Mythen, Catherine O’Malley, Anthony Roche, Kathy Rowan & Edward Burdett
Abstract Background Buffered intravenous fluid preparations contain substrates to maintain acid-base status. The objective of this systematic review was to compare the effects of buffered and non-buffered fluids administered during the perioperative period on clinical and biochemical outcomes. Methods We searched MEDLINE, EMBASE, CINAHL and the Cochrane Library until May 2017 and included all randomised controlled trials that evaluated buffered versus non-buffered fluids, whether crystalloid or colloid, administered to surgical patients. We assessed the selected...

Perioperative administration of buffered versus non-buffered crystalloid intravenous fluid to improve outcomes following adult surgical procedures: a Cochrane systematic review

Peter Odor, Sohail Bampoe, Ahilanandan Dushianthan, Elliott Bennett-Guerrero, Suzie Cro, Tong Gan, Michael Grocott, Michael James, Michael Mythen, Catherine O’Malley, Anthony Roche, Kathy Rowan & Edward Burdett
Abstract Background Buffered intravenous fluid preparations contain substrates to maintain acid-base status. The objective of this systematic review was to compare the effects of buffered and non-buffered fluids administered during the perioperative period on clinical and biochemical outcomes. Methods We searched MEDLINE, EMBASE, CINAHL and the Cochrane Library until May 2017 and included all randomised controlled trials that evaluated buffered versus non-buffered fluids, whether crystalloid or colloid, administered to surgical patients. We assessed the selected...

MOESM5 of The Plasmodium falciparum cytoplasmic translation apparatus: a promising therapeutic target not yet exploited by clinically approved anti-malarials

Christine Sheridan, Valentina Garcia, Vida Ahyong & Joseph DeRisi
Additional file 5. Method for PfIVT assay: step-by-step protocol.

Effect of a home-based exercise program on functional mobility and quality of life in elderly people: protocol of a single-blind, randomized controlled trial

Glauber Brandão, Luís Oliveira, Glaudson Brandão, Anderson Silva, Antônia Sampaio, Jessica Urbano, Alyne Soares, Newton Santos Faria, Luisa Pasqualotto, Ezequiel Oliveira, Rodrigo Oliveira, Deise Pires-Oliveira & Aquiles Camelier
Abstract Background Elderly people have high rates of functional decline, which compromises independence, self-confidence, and quality of life (QoL). Physical exercise leads to significant improvements in strength, balance, functional mobility, and QoL, but there is still reduced access to this therapeutic strategy due to difficulties in locomotion to training centers or lack of adaptation to the exercise environment. Methods/design The purpose of this clinical trial will be to verify the effect of a progressive and...

MOESM4 of The Plasmodium falciparum cytoplasmic translation apparatus: a promising therapeutic target not yet exploited by clinically approved anti-malarials

Christine Sheridan, Valentina Garcia, Vida Ahyong & Joseph DeRisi
Additional file 4. Flowchart for PfIVT extract quality control and pooling. Individual harvests are first tested at different magnesium concentrations; those that achieve 104 RLU activity threshold are pooled. Pooled extract is aliquoted, and a test aliquot is utilized to first determine ideal magnesium concentration, then ideal incubation time. Remaining aliquots are utilized for PfIVT assays at the determined magnesium & kinetic conditions.

Effect of a home-based exercise program on functional mobility and quality of life in elderly people: protocol of a single-blind, randomized controlled trial

Glauber Brandão, Luís Oliveira, Glaudson Brandão, Anderson Silva, Antônia Sampaio, Jessica Urbano, Alyne Soares, Newton Santos Faria, Luisa Pasqualotto, Ezequiel Oliveira, Rodrigo Oliveira, Deise Pires-Oliveira & Aquiles Camelier
Abstract Background Elderly people have high rates of functional decline, which compromises independence, self-confidence, and quality of life (QoL). Physical exercise leads to significant improvements in strength, balance, functional mobility, and QoL, but there is still reduced access to this therapeutic strategy due to difficulties in locomotion to training centers or lack of adaptation to the exercise environment. Methods/design The purpose of this clinical trial will be to verify the effect of a progressive and...

MOESM4 of The Plasmodium falciparum cytoplasmic translation apparatus: a promising therapeutic target not yet exploited by clinically approved anti-malarials

Christine Sheridan, Valentina Garcia, Vida Ahyong & Joseph DeRisi
Additional file 4. Flowchart for PfIVT extract quality control and pooling. Individual harvests are first tested at different magnesium concentrations; those that achieve 104 RLU activity threshold are pooled. Pooled extract is aliquoted, and a test aliquot is utilized to first determine ideal magnesium concentration, then ideal incubation time. Remaining aliquots are utilized for PfIVT assays at the determined magnesium & kinetic conditions.

MOESM3 of The Plasmodium falciparum cytoplasmic translation apparatus: a promising therapeutic target not yet exploited by clinically approved anti-malarials

Christine Sheridan, Valentina Garcia, Vida Ahyong & Joseph DeRisi
Additional file 3. Method for culturing and extract generation: step-by-step protocol.

Additional file 3: of Nursesâ perceptions towards the delivery and feasibility of a behaviour change intervention to enhance physical activity in patients at risk for cardiovascular disease in primary care: a qualitative study

Heleen Westland, Yvonne Koop, Carin SchrĂśder, Marieke Schuurmans, P. Slabbers, Jaap Trappenburg & Sigrid Vervoort
Consolidated criteria for reporting qualitative studies (COREQ). 32-item consolidated criteria for reporting qualitative studies (COREQ) (PDF 289â kb)

MOESM2 of The Plasmodium falciparum cytoplasmic translation apparatus: a promising therapeutic target not yet exploited by clinically approved anti-malarials

Christine Sheridan, Valentina Garcia, Vida Ahyong & Joseph DeRisi
Additional file 2. Flowchart of saponin batch calibration for erythrocyte lysis. Saponin amounts for RBC lysis are empirically determined through pairwise comparison for each preparation/batch of saponin. 3 to 5 harvests and pairwise tests will be required to determine the ideal amount of saponin for a given batch. Volumes indicated on the flowchart are for the volume of 0.15% saponin (in Buffer A) to be added to parasites in Buffer A and to a total...

MOESM3 of The Plasmodium falciparum cytoplasmic translation apparatus: a promising therapeutic target not yet exploited by clinically approved anti-malarials

Christine Sheridan, Valentina Garcia, Vida Ahyong & Joseph DeRisi
Additional file 3. Method for culturing and extract generation: step-by-step protocol.

Additional file 2: of Nursesâ perceptions towards the delivery and feasibility of a behaviour change intervention to enhance physical activity in patients at risk for cardiovascular disease in primary care: a qualitative study

Heleen Westland, Yvonne Koop, Carin SchrĂśder, Marieke Schuurmans, P. Slabbers, Jaap Trappenburg & Sigrid Vervoort
Checklist of criteria for good thematic analysis. 15-point checklist of criteria for good thematic analysis according to Braun and Clarke (PDF 303â kb)

Additional file 3: of Nursesâ perceptions towards the delivery and feasibility of a behaviour change intervention to enhance physical activity in patients at risk for cardiovascular disease in primary care: a qualitative study

Heleen Westland, Yvonne Koop, Carin SchrĂśder, Marieke Schuurmans, P. Slabbers, Jaap Trappenburg & Sigrid Vervoort
Consolidated criteria for reporting qualitative studies (COREQ). 32-item consolidated criteria for reporting qualitative studies (COREQ) (PDF 289â kb)

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