151 Works

Data from: Sexual imprinting: What strategies should we expect to see in nature?

Hayes Griffin, Robert Tucker Gilman, Dalton W. Chaffee & R. Tucker Gilman
Sexual imprinting occurs when juveniles learn mate preferences by observing the phenotypes of other members of their populations, and it is ubiquitous in nature. Imprinting strategies, that is which individuals and phenotypes are observed and how strong preferences become, vary among species. Imprinting can affect trait evolution and the probability of speciation, and different imprinting strategies are expected to have different effects. However, little is known about how and why different imprinting strategies evolve, or...

Data from: Self-cannulation for haemodialysis: patient attributes, clinical correlates and self-cannulation predilection models

Anuradha Jayanti, Philip Foden, Alison Wearden, Julie Morris, Paul Brenchley & Sandip Mitra
Background and objectives: With emerging evidence in support of home haemodialysis (HHD), patient factors which determine uptake of the modality need to be better understood. Self-cannulation (SC) is a major step towards enabling self-care ‘in-centre’ and home HD and remains the foremost barrier to its uptake. Human factors governing this aspect of HD practice are poorly understood. The aim of this study is to better understand self-cannulation preferences and factors which define them in end...

Data from: Plasticity in plant functional traits is shaped by variability in neighbourhood species composition

Maria Abakumova, Kristjan Zobel, Anu Lepik & Marina Semchenko
Plant functional traits can vary widely as a result of phenotypic plasticity to abiotic conditions. Trait variation may also reflect responses to the identity of neighbours, although not all species are equally responsive to their biotic surroundings. We hypothesized that responses to neighbours are shaped by spatial community patterns and resulting variability in neighbour composition. More precisely, we tested the theoretical prediction that plasticity is most likely to evolve if alternative environments (in this case,...

Data from: Grassland invasibility varies with drought effects on soil functioning

Maarten Schrama & Richard D. Bardgett
Although it is known that ecosystems are more susceptible to invasion when disturbed, our knowledge of the mechanisms involved remains limited. Recent studies indicate that disturbance-induced changes in soil nutrient availability could influence community invasibility, but the importance of this mechanism in the real world is not known. We tested the hypotheses that (i) exotic plant species profit from drought effects on soil functioning more than do natives; and (ii) grassland invasibility depends on soil...

Data from: A population genomics insight into the Mediterranean origins of wine yeast domestication

Pedro Almeida, Raquel Barbosa, Polona Zalar, Yumi Imanishi, Kiminori Shimizu, Benedetta Turchetti, Jean-Luc Legras, Marta Serra, Sylvie Dequin, Arnaud Couloux, Julie Guy, Douda Bensasson, Paula Gonçalves & José Paulo Sampaio
The domestication of the wine yeast Saccharomyces cerevisiae is thought to be contemporary with the development and expansion of viticulture along the Mediterranean basin. Until now, the unavailability of wild lineages prevented the identification of the closest wild relatives of wine yeasts. Here, we enlarge the collection of natural lineages and employ whole-genome data of oak-associated wild isolates to study a balanced number of anthropic and natural S. cerevisiae strains. We identified industrial variants and...

Data from: Colonization of the Mediterranean Basin by the vector biting midge species Culicoides imicola: an old story

Stephanie Jacquet, Claire Garros, Eric Lombaert, Catherine Walton, Johana Restrepo, Xavier Allene, Thierry Baldet, Catherine Cetre-Sossah, Alexandra Chaskopoulou, Jean-Claude Delecolle, Amelie Desvars, Mouloud Djerbal, Moussa Fall, Laetitia Gardes, Michel De Garine-Wichatitsky, Maria Goffredo, Yuval Gottlieb, Assane Gueye Fall, Muo Kasina, Karien Labuschagne, Youssef Lhor, Javier Lucientes, Thibaud Martin, Bruno Mathieu, Miguel Miranda … & Y. Gottlieb
Understanding the demographic history and genetic make-up of colonizing species is critical for inferring population sources and colonization routes. This is of main interest for designing accurate control measures in areas newly colonized by vector species of economically important pathogens. The biting midge Culicoides imicola is a major vector of orbiviruses to livestock. Historically, the distribution of this species was limited to the Afrotropical region. Entomological surveys first revealed the presence of C. imicola in...

Data from: The peripheral olfactory code in Drosophila larvae contains temporal information and is robust over multiple timescales

Micheline Grillet, Dario Campagner, Rasmus Petersen, Catherine McCrohan & Matthew Cobb
We studied the electrophysiological activity of two classes of Drosophila melanogaster larval olfactory sensory neurons (OSNs), Or24a and Or74a, in response to 1 s stimulation with butanol, octanol, 2-heptanone, and propyl acetate. Each odour/OSN combination produced unique responses in terms of spike count and temporal profile. We used a classifier algorithm to explore the information content of OSN activity, and showed that as well as spike count, the activity of these OSNs included temporal information...

Data from: Change and stability in a steep morph-frequency cline in the snail Cepaea nemoralis (L.) over 43 years.

Robert A. D. Cameron, Laurence M. Cook & Jeremy J. D. Greenwood
Populations of the polymorphic land snail Cepaea nemoralis (L.) from Deepdale, Derbyshire, UK, sampled in 1965-67, showed a pattern of area effects, with steep clines among groups of populations differing in shell colour and banding morph frequencies. In 2010 most of these populations were resampled. In particular a continuous transect made in 1967 of 42 18.34m x 18.34m quadrats across a steep cline in several morph frequencies was completely resampled. In the dale as a...

Data from: Evolution of mir-92a underlies natural morphological variation in Drosophila melanogaster

Saad Arif, Sophie Murat, Isabel Almudi, Maria D. S. Nunes, Diane Bortolamiol-Becet, Naomi S. McGregor, James M. S. Currie, Harri Hughes, Matthew Ronshaugen, Élio Sucena, Eric C. Lai, Christian Schlötterer & Alistair P. McGregor
eworoRL514BC_QTLPhenotype and genotype data for QTL mapping between strains e, wo, ro and RAL514.eworoRL514BC.xlsstsse_ORER_QTL_mapMap information for QTL mapping between strains st, ss, e and oregon R.ssste_ORER_QTL_crossCross information for QTL mapping between strains st, ss, e and oregon R.

Data from: Locomotory abilities and habitat of the Cretaceous bird Gansus yumenensis inferred from limb length proportions

Robert L. Nudds, Jessie Atterholt, Xia Wang, H. L. You, Gareth J. Dyke, J. Atterholt, R. L. Nudds, X. Wang & H.-L. You
The relative length proportions of the three bony elements of the pelvic (femur, tibiotarsus and tarsometatarsus) and pectoral (humerus, ulna and manus) limbs of the early Cretaceous bird Gansus yumenensis, a well-represented basal ornithuromorph from China are investigated and compared to those of extant taxa. Ternary plots show that the pectoral limb length proportions of Gansus are most similar to Apodiformes (swifts and hummingbirds), which plot away from all other extant birds. In contrast, the...

Financing Community Energy Case Studies : Brighton and Hove Energy Services (BHESCo)

Iain Cairns, Matthew Hannon, Timothy Braunholtz-Speight, Carly McLachlan, Sarah Mander, Edward Manderson, Maria Sharmina & Jeff Hardy
This report presents the final of four case studies of UK community energy organisations conducted during 2018/19, which will later be included as part of a synthesis briefing alongside a series of sector-level interviews. The case study makes use of a combination of qualitative (e.g. interviews, organisation reports) and quantitative (e.g. financial reports) data. Summary of key lessons includes: Energy efficiency and heating services can constitute a core offering of community groups. Unlike many other...

Data from: Evaluation of a pharmacist-led actionable audit and feedback intervention for improving medication safety in primary care: an interrupted time series analysis

Niels Peek
Background. We evaluated the impact of a pharmacist-led Safety Medication dASHboard (SMASH) intervention on medication safety in primary care. Methods and findings. SMASH comprised: (1) training of clinical pharmacists to deliver the intervention; (2) a web-based dashboard providing actionable, patient-level feedback; and (3) pharmacists reviewing individual at-risk patients, and initiating remedial actions or advising general practitioners on doing so. It was implemented in forty-three general practices covering a population of 235,595 people in Salford (Greater...

Financing Community Energy Case Studies : Gwent Energy CIC

Iain Cairns, Matthew Hannon, Timothy Braunholtz-Speight, Carly McLachlan, Sarah Mander, Edward Manderson, Maria Sharmina & Jeff Hardy
This report presents the third of four case studies of UK community energy organisations conducted during 2018/19. These will later be included as part of a synthesis briefing alongside a series of sector-level interviews. The case study makes use of a combination of qualitative (e.g. interviews, organisation reports) and quantitative (e.g. financial reports) data. Summary of key lessons: The withdrawal of the FiT has made business model innovation necessary, whilst legacy revenues from the FiT...

Data from: Reconstructing Asian faunal introductions to eastern Africa from multi-proxy biomolecular and archaeological datasets

Mary E. Prendergast, Michael Buckley, Alison Crowther, Heidi Eager, Laurent Frantz, Ophélie Lebrasseur, Rainer Hutterer, Ardern Hulme-Beaman, Wim Van Neer, Katerina Douka, Margaret-Ashley Veall, Eréndira M. Quintana Morales, Verena J. Schuenemann, Ella Reiter, Richard Allen, Evangelos A. Dimopoulos, Richard M. Helm, Ceri Shipton, Ogeto Mwebi, Christiane Denys, Mark C. Horton, Stephanie Wynne-Jones, Jeffrey Fleisher, Chantal Radimilahy, Henry Wright … & Mark Horton
Human-mediated biological exchange has had global social and ecological impacts. In sub-Saharan Africa, several domestic and commensal animals were introduced from Asia in the pre-modern period; however, the timing and nature of these introductions remain contentious. One model supports introduction to the eastern African coast after the mid-first millennium CE, while another posits introduction dating back to 3000 BCE. These distinct scenarios have implications for understanding the emergence of long-distance maritime connectivity, and the ecological...

Atmospheric gas and vegetation survey data from Parsonage Down, UK, in 2014

E.L. Fry, A.L. Hall, J. Savage, R.D. Bardgett, N. Ostle, R.F. Pywell, J.M. Bullock & S. Oakley
This dataset contains greenhouse gas flux data and vegetation survey data from an experiment based at Parsonage Down, UK. The vegetation survey comprises total species percentage cover and species richness data from four 50 cm by 50 cm quadrats. The greenhouse gas flux data comprises net ecosystem carbon dioxide exchange, photosynthesis and respiration data measured with an Infra-red Gas Analyser (IRGA); methane, carbon dioxide and nitrous oxide data measured using gas chromatography; and nitrate and...

Data from: Small airway dysfunction in well-treated never-smoking HIV-infected individuals

Andreas Ronit, Inger Hee Mathiesen, Marco Gelpi, Thomas Benfield, Jan Gerstoft, Tacjana Pressler, Anders Christiansen, Jens Lundgren, Jørgen Vestbo & Susanne Dam Nielsen
Global projections from the World Health Organization rank chronic obstructive pulmonary disease (COPD) and HIV as the third and eighth leading causes of death by 2030, respectively. An increasingly large number of individuals will consequently face a double burden of disease. The incidence of COPD is relatively high in the HIV-infected population, and HIV has been shown to be an independent risk factor.

Data from: Environment and host as large-scale controls of ectomycorrhizal fungi

Sietse Van Der Linde, Laura M. Suz, C. David L. Orme, Filipa Cox, Henning Andreae, Endla Asi, Bonnie Atkinson, Sue Benham, Christopher Carroll, Nathalie Cools, Bruno De Vos, Hans-Peter Dietrich, Johannes Eichhorn, Joachim Germann, Tine Grebenc, Hyun S. Gweon, Karin Hansen, Frank Jacob, Ferdinand Kristöfel, Pawel Lech, Miklos Manninger, Jan Martin, Henning Meesenburg, Päivi Merilä, Manuel Nicolas … & Martin I. Bidartondo
Explaining the large-scale diversity of soil organisms that drive biogeochemical processes—and their responses to environmental change—is critical. However, identifying consistent drivers of belowground diversity and abundance for some soil organisms at large spatial scales remains problematic. Here we investigate a major guild, the ectomycorrhizal fungi, across European forests at a spatial scale and resolution that is—to our knowledge—unprecedented, to explore key biotic and abiotic predictors of ectomycorrhizal diversity and to identify dominant responses and thresholds...

Data from: Enzyme replacement therapy and white matter hyperintensity progression in Fabry disease

James D. Stefaniak, Laura M. Parkes, Adrian R. Parry-Jones, Gillian M. Potter, Andy Vail, Ana Jovanovic & Craig J. Smith
Objective: To explore the association between Enzyme Replacement Therapy (ERT), clinical characteristics and the rate of progression of White Matter Hyperintensities (WMHs) in Fabry disease (FD) patients. Methods: Patients with a confirmed diagnosis of FD, aged >18 years, participating in an existing FD observational study (NCT00196742), with at least two serial MRI brain scans at least 2 years apart for the period between December 2006 and August 2016 were included in this cohort study. Total...

Data from: Parsimony, not Bayesian analysis, recovers more stratigraphically congruent phylogenetic trees

Robert S. Sansom, Peter G. Choate, Joseph N. Keating & Emma Randle
Reconstructing evolutionary histories requires accurate phylogenetic trees. Recent simulation studies suggest that probabilistic phylogenetic analyses of morphological data are more accurate than traditional parsimony techniques. Here we use empirical data to compare Bayesian and parsimony phylogenies in terms of their congruence with the distribution of age ranges of the component taxa. Analysis of 167 independent morphological data matrices of fossil tetrapods finds that Bayesian trees exhibit significantly lower stratigraphic congruence than the equivalent parsimony trees....

Data from: Sexual conflict and ecology: species composition and male density interact to reduce male mating harassment and increase female survival

Miguel Gomez, Hanna Mercedes Bensch, Erik I. Svensson, Miguel A. Gomez-Llano & Hanna M. Bensch
Sexual conflict is a pervasive evolutionary force that can reduce female fitness. Experimental evolution studies in the laboratory might overestimate the importance of sexual conflict since the ecological conditions in such settings typically include only a single species. Here, we experimentally manipulated conspecific male density (high or low) and species composition (sympatric or allopatric) to investigate how ecological conditions affect female survival in a sexually dimorphic insect, the banded demoiselle (Calopteryx splendens). Female survival was...

Data from: Soil organic carbon dynamics matching ecological equilibrium theory

Tancredi Caruso, Franciska T De Vries, Richard D Bardgett, Johannes Lehmann, Franciska T. De Vries & Richard D. Bardgett
The persistence of soil organic carbon (SOC) has traditionally been explained as a combination of recalcitrance properties and stabilization processes, which lead to the formation of complex organic compounds. However, recent conceptual advances and experimental evidence challenge this view. Here, we test these conceptual advances using a dynamic equilibrium theory of SOC founded on classic ecological theory. We postulate that the persistence of SOC is an equilibrium point where SOC losses resulting from continuous decomposition...

Data from: Molecular insights into genome-wide association studies of chronic kidney disease-defining traits

Xiaoguang Xu, James M. Eales, Artur Akbarov, Hui Guo, Lorenz Becker, David Talavera, Fezhan Ashraf, Jabran Nawaz, Sanjeev Pramanik, John Bowes, Xiao Jiang, John Dormer, Matthew Denniff, Andrzej Antczak, Monika Szulinska, Ingrid Wise, Priscilla R. Prestes, Maciej Glyda, Pawel Bogdanski, Ewa Zukowska-Szczechowska, Carlo Berzuini, Adrian S. Woolf, Nilesh J. Samani, Fadi J. Charchar & Maciej Tomaszewski
Genome-wide association studies (GWAS) have identified >100 loci of chronic kidney disease-defining traits (CKD-dt). Molecular mechanisms underlying these associations remain elusive. Using 280 kidney transcriptomes and 9958 gene expression profiles from 44 non-renal tissues we uncover gene expression partners (eGenes) for 88.9% of CKD-dt GWAS loci. Through epigenomic chromatin segmentation analysis and variant effect prediction we annotate functional consequences to 74% of these loci. Our colocalisation analysis and Mendelian randomisation in >130,000 subjects demonstrate causal...

Dominant native and non-native graminoids differ in key leaf traits irrespective of nutrient availability

Arthur Broadbent, Jennifer Firn, James McGree, Elizabeth Borer, Yvonne Buckley, W. Stanley Harpole, Kimberly Komatsu, Andrew MacDougall, Kate Orwin, Nicholas Ostle, Eric Seabloom, Jonathan Bakker, Lori Biedermann, Maria Caldeira, Nico Eisenhauer, Nicole Hagenah, Yann Hautier, Joslin Moore, Carla Nogueira, Pablo Peri, Anita Risch, Christiane Roscher, Martin Schuetz & Carly Stevens
Aim Nutrient enrichment is associated with plant invasions and biodiversity loss. Functional trait advantages may predict the ascendancy of invasive plants following nutrient enrichment but this is rarely tested. Here, we investigate 1) whether dominant native and non-native plants differ in important morphological and physiological leaf traits, 2) how their traits respond to nutrient addition, and 3) whether responses are consistent across functional groups. Location Australia, Europe, North America and South Africa Time period 2007...

Data from: Chemical signals from eggs facilitate cryptic female choice in humans

John Fitzpatrick, Charlotte Willis, Alessandro Devigili, Amy Young, Michael Carroll, Helen Hunter & Daniel Brison
Mate choice can continue after mating via chemical communication between the female reproductive system and sperm. While there is a growing appreciation that females can bias sperm use and paternity by exerting cryptic female choice for preferred males, we know surprisingly little about the mechanisms underlying these post-mating choices. In particular, whether chemical signals released from eggs (chemoattractants) allow females to exert cryptic female choice to favour sperm from specific males remains an open question,...

Data from: A multi-breed genome-wide association analysis for canine hypothyroidism identifies a shared major risk locus on CFA12

Matteo Bianchi, Stina Dahlgren, Jonathan Massey, Elisabeth Dietschi, Marcin Kierczak, Martine Lund-Ziener, Katarina Sundberg, Stein Istre Thoresen, Olle Kämpe, Göran Andersson, William E. R. Ollier, Åke Hedhammar, Tosso Leeb, Kerstin Lindblad-Toh, Lorna J. Kennedy, Frode Lingaas, Gerli Rosengren Pielberg & Stein Istre Thoresen
Bianchi, Dahlgren et al., Canine Hypothyroidism data

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