1,631 Works

blog

Henry Rzepa
Portal project

isoQ_Lactone_chair_Product_1 (opt freq)

Bethan Coulson
Gaussian Calculation

Jordi

Henry Rzepa
Portal project

Data Repository Project

Henry Rzepa
A FAIR Data project involving the design and deployment of a data repository containing enhanced features.

Data from: Environmental drivers of crocodyliform extinction across the Jurassic/Cretaceous transition

Jonathan P. Tennant, Philip D. Mannion & Paul Upchurch
Crocodyliforms have a much richer evolutionary history than represented by their extant descendants, including several independent marine and terrestrial radiations during the Mesozoic. However, heterogeneous sampling of their fossil record has obscured their macroevolutionary dynamics, and obfuscated attempts to reconcile external drivers of these patterns. Here, we present a comprehensive analysis of crocodyliform biodiversity through the Jurassic/Cretaceous (J/K) transition using subsampling and phylogenetic approaches and apply maximum-likelihood methods to fit models of extrinsic variables to...

Data from: Evidence for parasite-mediated selection during short-lasting toxic algal blooms

François Blanquart, Myriam Valero, Catharina Alves-De-Souza, Aliou Dia, Frédéric Lepelletier, Estelle Bigeard, Christian Jeanthon, Christophe Destombe & Laure Guillou
Parasites play a role in the control of transient algal blooms, but it is not known whether parasite-mediated selection results in coevolution of the host and the parasites over this short time span. We investigated the presence of coevolution between the toxic dinoflagellate Alexandrium minutum and two naturally occurring endoparasites during blooms lasting a month in two river estuaries, using cross-inoculation experiments across time and space. Higher parasite abundance was associated with a large daily...

Data from: Quantifying species contributions to ecosystem processes: a global assessment of functional trait and phylogenetic metrics across avian seed-dispersal networks

Alexander L. Pigot, Tom Bregman, Catherine Sheard, Benjamin Daly, Rampal S. Etienne & Joseph A. Tobias
Quantifying the role of biodiversity in ecosystems not only requires understanding the links between species and the ecological functions and services they provide, but also how these factors relate to measurable indices, such as functional traits and phylogenetic diversity. However, these relationships remain poorly understood, especially for heterotrophic organisms within complex ecological networks. Here, we assemble data on avian traits across a global sample of mutualistic plant–frugivore networks to critically assess how the functional roles...

Data from: Assessment of available anatomical characters for linking living mammals to fossil taxa in phylogenetic analyses

Thomas Guillerme & Natalie Cooper
Analyses of living and fossil taxa are crucial for understanding biodiversity through time. The total evidence method allows living and fossil taxa to be combined in phylogenies, using molecular data for living taxa and morphological data for living and fossil taxa. With this method, substantial overlap of coded anatomical characters among living and fossil taxa is vital for accurately inferring topology. However, although molecular data for living species are widely available, scientists generating morphological data...

Data from: Temporal and phylogenetic evolution of the sauropod dinosaur body plan

Karl T. Bates, Philip D. Mannion, Peter L. Falkingham, Stephen L. Brusatte, John R. Hutchinson, Alexandros Otero, William I. Sellers, Corwin Sullivan, Kent A. Stevens & Vivian Allen
The colossal size and body plan of sauropod dinosaurs are unparalleled in terrestrial vertebrates. However, to date, there have been only limited attempts to examine temporal and phylogenetic patterns in the sauropod bauplan. Here, we combine three-dimensional computational models with phylogenetic reconstructions to quantify the evolution of whole-body shape and body segment properties across the sauropod radiation. Limitations associated with the absence of soft tissue preservation in fossils result in large error bars about mean...

Data from: Variation in relapse frequency and the transmission potential of Plasmodium vivax malaria

Michael T. White, George Shirreff, Stephan Karl, Azra C. Ghani & Ivo Mueller
There is substantial variation in the relapse frequency of Plasmodium vivax malaria, with fast relapsing strains in tropical areas, and slow relapsing strains in temperate areas with seasonal transmission. We hypothesise that much of the phenotypic diversity in P. vivax relapses arises from selection of relapse frequency to optimise transmission potential in a given environment, in a process similar to the virulence trade-off hypothesis. We develop mathematical models of P. vivax transmission and calculate the...

Data from: Epistasis between antibiotic resistance mutations and genetic background shape the fitness effect of resistance across species of Pseudomonas

Tom Vogwill, Mila Kojadinovic, R. Craig MacLean, R. C. MacLean & T. Vogwill
Antibiotic resistance often evolves by mutations at conserved sites in essential genes, resulting in parallel molecular evolution between divergent bacterial strains and species. Whether these resistance mutations are having parallel effects on fitness across bacterial taxa, however, is unclear. This is an important point to address, because the fitness effects of resistance mutations play a key role in the spread and maintenance of resistance in pathogen populations. We address this idea by measuring the fitness...

Data from: Divergent trophic responses to biogeographic and environmental gradients

Miguel G. Matias, Cátia Lúcio Pereira, Pedro Miguel Raposeiro, Vítor Gonçalves, Ana Mafalda Cruz, Ana Cristina Costa & Miguel Bastos Araújo
Following environmental changes, communities disassemble and reassemble in seemingly unpredictable ways. Whether species respond to such changes individualistically or collectively (e.g. as functional groups) is still unclear. To address this question, we used an extensive new dataset for the lake communities in the Azores' archipelago to test whether: 1) individual species respond concordantly within trophic groups; 2) trophic groups respond concordantly to biogeographic and environmental gradients. Spatial concordance in individual species distributions within trophic groups...

Data from: Bacterial competition and quorum-sensing signalling shapes the eco-evolutionary outcomes of model in vitro phage therapy

Rachel Mumford & Ville-Petri Friman
The rapid rise of antibiotic resistance has renewed interest in phage therapy – the use of bacteria-specific viruses (phages) to treat bacterial infections. Even though phages are often pathogen-specific, little is known about the efficiency and eco-evolutionary outcomes of phage therapy in polymicrobial infections. We studied this experimentally by exposing both quorum sensing (QS) signalling PAO1 and QS-deficient lasR Pseudomonas aeruginosa genotypes (differing in their ability to signal intra-specifically) to lytic PT7 phage in the...

Data from: Divergent evolution peaks under intermediate population bottlenecks during bacterial experimental evolution

Tom Vogwill, Robyn L. Phillips, Danna R. Gifford & R. Craig MacLean
There is growing evidence that parallel molecular evolution is common, but its causes remain poorly understood. Demographic parameters such as population bottlenecks are predicted to be major determinants of parallelism. Here, we test the hypothesis that bottleneck intensity shapes parallel evolution by elucidating the genomic basis of adaptation to antibiotic-supplemented media in hundreds of populations of the bacterium Pseudomonas fluorescens Pf0-1. As expected, bottlenecking decreased the rate of phenotypic and molecular adaptation. Surprisingly, bottlenecking had...

Data from: Patterns of mammalian population decline inform conservation action

Martina M. I. Di Fonzo, Ben Collen, Alienor L. M. Chauvenet & Georgina M. Mace
1. Evaluations of wildlife population dynamics have the potential to convey valuable information on the type of pressure affecting a population and could help predict future changes in the population's trajectory. Greater understanding of different patterns of population declines could provide a useful mechanism for assessing decline severity in the wild and identifying those populations that are more likely to exhibit severe declines. 2. We identified 93 incidences of decline within 75 populations of mammalian...

Triplet polymers_full side chains

Rolf Andernach
Portal project

PPY 631Gdp geom opt

Rolf Andernach
Gaussian Calculation

High-resolution satellite-gauge merged precipitation climatologies of the tropical Andes

B. Manz, W. Buytaert, Z. Zulkafli, W. Lavado, B. Willems, A. Robles L. & J.-P. Rodríguez Sánchez
A set of 130 digital precipitation maps of the tropical Andes, covering Colombia, Ecuador and Peru at a 5km resolution. The maps represent different realizations of mean precipitation totals of the period 1981-2010 using different satellite-gauge merging methods. The work draws on a large database of 723 rain gauges and the full 5km Tropical Rainfall Measuring Mission (TRMM) Precipitation Radar (TPR) record from 1998 to 2014. Each map is approximately 1MB

Di-axial elimination of F IRC

Henry Rzepa
Gaussian Calculation

TS optimisation pre-calculation

Bethan Coulson
Gaussian Calculation

IRC_isoB_SO2py_boat_1 (IRC)

Bethan Coulson
Gaussian Calculation

trimethyloxonium + Br(-) TS Def2-TZVPPD

Henry Rzepa
Gaussian Calculation

isoH_Product_1 (opt freq)

Bethan Coulson
Gaussian Calculation

Product for cis ring fusion, SnCl3

Henry Rzepa
Gaussian Calculation, b3lyp/def2tzvpp/scrf=(cpcm,solvent=dichloromethane) empiricaldispersion=gd3bj method.

Intermediate for cis ring fusion, SnCl3

Henry Rzepa
Gaussian Calculation, b3lyp/def2tzvpp/scrf=(cpcm,solvent=dichloromethane) empiricaldispersion=gd3bj method.

Registration Year

  • 2016
    1,631

Resource Types

  • Dataset
    1,576
  • Collection
    55

Affiliations

  • Imperial College London
    1,631
  • University of Oxford
    3
  • University College London
    2
  • Institute of Vertebrate Paleontology and Paleoanthropology
    1
  • National University of San Marcos
    1
  • University of Queensland
    1
  • University of Groningen
    1
  • Natural History Museum
    1
  • Walter and Eliza Hall Institute of Medical Research
    1
  • University of Edinburgh
    1
  • Royal Veterinary College
    1
  • University of Manchester
    1
  • University of Oregon
    1
  • Sorbonne University
    1
  • French National Centre for Scientific Research
    1