Supplemental material, sj-docx-1-chl-10.1177_17475198221131289 for A one-step method for preparing Cr-doped SiO2: An efficient catalyst for the direct oxidation of cyclohexane to ketone-alcohol oil by Xiaozhong Wang, Kaicheng Xue, Cai Xu, Yingqi Chen and Liyan Dai in Journal of Chemical Research

Additional file 2. World Health Organization Trial Registration Data Set: Make Better Choices 2 (MBC2) for Rural Appalachians.

Abstract Background Rural Appalachian residents experience among the highest prevalence of chronic disease, premature mortality, and decreased life expectancy in the nation. Addressing these growing inequities while avoiding duplicating existing programming necessitates the development of appropriate adaptations of evidence-based lifestyle interventions. Yet few published articles explicate how to accomplish such contextual and cultural adaptation. Methods In this paper, we describe the process of adapting the Make Better Choices 2 (MBC2) mHealth diet and activity randomized...

Supplemental material, sj-docx-1-wmr-10.1177_0734242X221129054 for Thermal degradation and combustion properties of most popular synthetic biodegradable polymers by Hongmei Chen, Fengyi Chen, Hui Chen, Hongsheng Liu, Ling Chen and Long Yu in Waste Management & Research

Abstract Background Diverse drug vulnerabilities owing to the Chromatin regulators (CRs) genetic interaction across various cancers, but the identification of CRs genetic interaction remains challenging. Methods In order to provide a global view of the CRs genetic interaction in cancer cells, we developed a method to identify potential drug response-related CRs genetic interactions for specific cancer types by integrating the screen of CRISPR-Cas9 and pharmacogenomic response datasets. Results Totally, 625 drug response-related CRs synthetic lethality...

Additional file 1: Figure S1. The length of all identified ubiquitinated peptides. Figure S2. The numbers of all identified spectrums, peptides and proteins. Figure S3. The screening of potential functional ubiquitination in CRC patients.

Prolonged infection and possible evolution of SARS-CoV-2 in patients living with uncontrolled HIV-1 infection highlight the importance of an effective vaccination regimen, yet the immunogenicity of COVID-19 vaccines and predictive immune biomarkers have not been well investigated. Herein, we report that the magnitude and persistence of antibody and cell-mediated immunity (CMI) elicited by an Ad5-vectored COVID-19 vaccine are impaired in SIV-infected macaques with high viral loads (> 105 genome copies per ml plasma, SIVhi) but...

Prolonged infection and possible evolution of SARS-CoV-2 in patients living with uncontrolled HIV-1 infection highlight the importance of an effective vaccination regimen, yet the immunogenicity of COVID-19 vaccines and predictive immune biomarkers have not been well investigated. Herein, we report that the magnitude and persistence of antibody and cell-mediated immunity (CMI) elicited by an Ad5-vectored COVID-19 vaccine are impaired in SIV-infected macaques with high viral loads (> 105 genome copies per ml plasma, SIVhi) but...

The principal goal of the present investigation was to enterprise new and effective drug delivery vesicle for the sustained delivery of local anesthetic lidocaine hydrochloride (LDC), using a novel combination of copolymeric hydrogel with tetrahydroxyborate (COP–THB) to improve bioactivity and therapeutic potential. To support this contention, the physical and mechanical properties, rheological characteristics, and component release of candidate formulations were investigated. An optimized formulation of COP–THB containing LDC to an upper maximum concentration of 1.5%...

β-galactosidase catalyzes lactose hydrolysis and transfers reactions to produce prebiotics such as galacto-oligosaccharides (GOS) with potential applications in the food industry and pharmaceuticals. However, there is still a need for improved transgalactosylation activity of β-galactosidases and reaction conditions of GOS production in order to maximize GOS output and reduce production costs. In this study, a β-galactosidase gene, galA, from Bacillus circulans was expressed in Pichia pastoris, which not only hydrolyzed lactose but also had strong...

Qingre Huoxue (QRHX) decoction, a traditional Chinese medicine, has been widely used to prevent and treat myocardial infarction (MI). This study elucidates the possible mechanisms of QRHX in preventing or treating MI in a rat model. The chemical constituents of QRHX were identified by UPLC-MS. Sprague-Dawley rats were randomly divided into the Sham (normal saline), Model (normal saline), QRHX-L, QRHX-M and QRHX-H group (n = 10 per group). QRHX decoction was administered by gavage to...

Costs for obstetrical care may be increasing for both patients and insurers. To examine predictors of and trends in the cost of medical care during pregnancy. We performed a study of pregnancies from 2009 to 2019 covered by commercial insurance resulting in term, singleton delivery hospitalizations and included in the MarketScan database. The analysis categorized pregnancies based on whether delivery occurred via cesarean versus vaginal delivery and whether pre-gestational diabetes or chronic hypertension was present....

A novel tumor-targeted glutathione responsive Glycosylated-Camptothecin nanosupramolecular prodrug (CPT-GL NSp) was designed and fabricated via a disulfide bond. The effects of glycoligand with different polarities on solubility, self-assembly, stability, cellular uptake, and glutathione responsive cleaving were explored, and an optimal glycosylated ligand was selected for nanosupramolecular prodrug. It has been found that CPT-GL NSp exhibited higher drug loading than traditional nanoparticles. Among of which maltose modified NSp had the strongest anti-tumor effects than that of...

Really Interesting New Gene (RING) proteins are referred to as CHY zinc and ring finger protein (CHYR) members because they have the CHY domain, a type of protein that responds to abiotic stress. However, there are scant data on CHYR members in Phaseolus vulgaris (common bean). This study identified eight CHYR members (PvCHYRs) in the reference genome. A comprehensive analysis was performed to determine function, location, basic information, evolution, motifs, gene structure, cis-acting elements, collinearity,...

Really Interesting New Gene (RING) proteins are referred to as CHY zinc and ring finger protein (CHYR) members because they have the CHY domain, a type of protein that responds to abiotic stress. However, there are scant data on CHYR members in Phaseolus vulgaris (common bean). This study identified eight CHYR members (PvCHYRs) in the reference genome. A comprehensive analysis was performed to determine function, location, basic information, evolution, motifs, gene structure, cis-acting elements, collinearity,...

Epidemiological and interventional studies have been rarely conducted among those with positive interferon-γ release assay (IGRA) results and radiologically inactive tuberculosis (TB) lesions on chest radiograph. This study aimed to estimate the effectiveness and safety of a six-week twice-weekly regimen (rifapentine plus isoniazid) among this key population in rural China. First, chest digital radiography was conducted to screen individuals with inactive TB lesions. Then, the identified participants were further evaluated and eligible participants with IGRA-positive...

Some equations about the construction of the diffuser sheet model

Light-emitting diodes (LEDs) are the 4th plant supplemental lighting source. Pulsed lighting is benefit to increase energy utilization efficiency in greenhouse production. A pulsed-lighting LED luminaire with geometrical optical solution is proposed to overcome the shortcoming with pulse width modulation (PWM) solution. In addition, this luminaire also achieves uniform lighting by designing freeform surfaces. In the illumination area, the lighting frequency is 117.6 Hz and the illuminance uniformity is 0.789, which is better than 0.75...

Light-emitting diodes (LEDs) are the 4th plant supplemental lighting source. Pulsed lighting is benefit to increase energy utilization efficiency in greenhouse production. A pulsed-lighting LED luminaire with geometrical optical solution is proposed to overcome the shortcoming with pulse width modulation (PWM) solution. In addition, this luminaire also achieves uniform lighting by designing freeform surfaces. In the illumination area, the lighting frequency is 117.6 Hz and the illuminance uniformity is 0.789, which is better than 0.75...

The evaluation of megakaryocytes is an important part of the work up on bone marrow smear examination. It has significance in the differential diagnosis, therapeutic efficacy assessment, and predication of prognosis of many hematologic diseases. The process of manual identification of megakaryocytes are tedious and lack of reproducibility; therefore, a reliable method of automated megakaryocytic identification is urgently needed. Three hundred and thirty-three bone marrow aspirate smears were digitized by Morphogo system. Pathologists annotated megakaryocytes...

Supplemental Material for Epidemiological and clinical characteristics of vaccinated COVID-19 patients: A meta-analysis and systematic review by Wen Tian, Xingxiang Ren, Mei Han, Yuanyuan Zhang, Xu Gao, Zhihai Chen, and Wei Zhang in International Journal of Immunopathology and Pharmacology

A catastrophic flood occurred on 7 February 2021 around 10:30 AM (local time) in the Rishiganga River, which has been attributed to a rockslide in the upper reach of the Raunthi River. The Resourcesat 2 LISS IV (8 February 2021) and CNES Airbus satellite imagery (9 February 2021) clearly show the location of displaced materials. The solar radiation observed was higher than normal by 10% and 25% on 6 and 7 February 2021, respectively, however,...

Home and community-based services (HCBS) assist people with disabilities and older adults to remain in their homes. Direct support professionals and care managers who facilitate the development of support plans need to employ person-centered approaches to ensure services are tailored to peoples’ needs and preferences. The aims were to identify the key competencies needed for delivery of person-centered supports and examine the relationship between HCBS and its’ outcomes in the United States. We used the...

Supplemental material, sj-docx-1-acr-10.1177_02841851211065142 for MRI-based radiomics analysis to evaluate the clinicopathological characteristics of cervical carcinoma: a multicenter study by Yi Liu, Ting Song, Tian-Fa Dong, Wei Zhang and Ge Wen in Acta Radiologica

Additional file 1 .