3 Works

Data from: Predictors of new remote cerebral microbleeds after intravenous thrombolysis for ischemic stroke

Tim Bastian Braemswig, Kersten Villringer, Guillaume Turc, Hebun Erdur, Jochen B. Fiebach, Heinrich J. Audebert, Matthias Endres, Christian H. Nolte & Jan F. Scheitz
Objective: To assess the frequency, associated factors, and underlying vasculopathy of new remote cerebral microbleeds (CMB), as well as the risk of concomitant hemorrhagic complications related to new CMBs, after intravenous thrombolysis (IVT) in acute stroke patients. Methods: We conducted an observational study using data from our local thrombolysis registry. We included consecutive stroke patients with MRI (3-Tesla)-based IVT and a follow-up MRI the next day between 2008–2017 (n=396). Only CMBs located outside of the...

Data from: Hodge decomposition of wall shear stress vector fields characterizing biological flows

Faniry H. Razafindrazaka, Pavel Yevtushenko, Konstantin Poelke, Konrad Polthier & Leonid Goubergrits
A discrete boundary-sensitive Hodge decomposition is proposed as a central tool for the analysis of wall shear stress (WSS) vector fields in aortic blood flows. The method is based on novel results for the smooth and discrete Hodge-Morrey-Friedrichs decomposition on manifolds with boundary and subdivides the WSS vector field into five components: gradient (curl-free), co-gradient (divergence-free), and three harmonic fields induced from the boundary, which are called the center, Neumann and Dirichlet fields. First, an...

Data from: Immune checkpoint inhibitor–related myositis and myocarditis in patients with cancer

Mehdi Touat, Thierry Maisonobe, Samuel Knauss, Omar Ben Hadj Salem, Baptiste Hervier, Karine Auré, Tali-Anne Szwebel, Nora Kramkimel, Claire Lethrosne, Jean-Frédéric Bruch, Pauline Laly, Jacques Cadranel, Nicolas Weiss, Anthony Béhin, Yves Allenbach, Olivier Benveniste, Timothée Lenglet, Dimitri Psimaras, Werner Stenzel & Sarah Léonard-Louis
Objective: To report the clinicopathological features and outcome of myositis in patients treated with immune checkpoint inhibitors (irMyositis). Methods: We retrospectively analyzed patients diagnosed with irMyositis in tertiary centers in Paris, France, and Berlin, Germany, from January 2015, to July 2017. Main outcomes were clinical manifestations and muscle histology, which included MHC-I, C5b-9, CD3, CD4, CD8, CD20, CD68, PD-1, PD-L1 and PD-L2 immunohistochemical stains. Results: Ten patients with metastatic cancer were included; median age was...

Registration Year

  • 2018
    3

Resource Types

  • Dataset
    3

Affiliations

  • Charité
    3
  • Inserm
    2
  • Hôpital Cochin
    1
  • Humboldt University of Berlin
    1
  • CHU Ambroise Paré
    1
  • Sorbonne University
    1
  • Centre d'Immunologie et des Maladies Infectieuses
    1
  • Harvard Medical School
    1
  • Freie Universität Berlin
    1
  • Berlin Institute of Health
    1