138 Works

L’icnosito della località “Foresta” di Tora e Piccilli e le impronte umane fossili

Adolfo Panarello, Gennaro Farinaro & Paolo Mietto
This report provides a complete description of the general “Ciampate del diavolo” palaeontological site (Tora e Piccilli, Central-Southern Italy) and each of the human ichnites there found so far. This description is integrated and completed with the tables, graphs, and pictures given in Supplements 1, 2, and 3 of this volume [Panarello et al., 2022a;b;c]. We think that this huge amount of both numeric and visual data will be very useful for any other human...

Segni umani recenti sulla pendice delle orme preistoriche

Paolo Mietto & Adolfo Panarello
The various on-field activities which have been carried out by researchers in the “Devil’s Trails” palaeontological site from 2005 to 2010 and the subsequent Ph.D. researches on the site that took place until 2016 have allowed us to identify - in addition to the various ichnological evidence of prehistoric times - also a series of anthropic cuts made in various historical times. These cuts sometimes overlap the prehistoric traces, or partially alter them, so creating...

Mnamon: Cuneiforme sumerico

Salvatore Gaspa
Introduzione critica al cuneiforme sumerico, risorse elettroniche e bibliografia.

Synaptic alterations in visual cortex reshape contrast-dependent gamma oscillations and inhibition-excitation ratio in a genetic mouse model of migraine

Nicolò Meneghetti, Chiara Cerri, Eleonora Vannini, Elena Tantillo, Angelita Tottene, Daniela Pietrobon, Matteo Caleo & Alberto Mazzoni
Abstract Background Migraine affects a significant fraction of the world population, yet its etiology is not completely understood. In vitro results highlighted thalamocortical and intra-cortical glutamatergic synaptic gain-of-function associated with a monogenic form of migraine (familial-hemiplegic-migraine-type-1: FHM1). However, how these alterations reverberate on cortical activity remains unclear. As altered responsivity to visual stimuli and abnormal processing of visual sensory information are common hallmarks of migraine, herein we investigated the effects of FHM1-driven synaptic alterations in...

sj-pdf-1-pss-10.1177_09567976221097947 – Supplemental material for Severe Developmental Dyscalculia Is Characterized by Core Deficits in Both Symbolic and Nonsymbolic Number Sense

Gisella Decarli, Francesco Sella, Silvia Lanfranchi, Giulia Gerotto, Silvia Gerola, Giuseppe Cossu & Marco Zorzi
Supplemental material, sj-pdf-1-pss-10.1177_09567976221097947 for Severe Developmental Dyscalculia Is Characterized by Core Deficits in Both Symbolic and Nonsymbolic Number Sense by Gisella Decarli, Francesco Sella, Silvia Lanfranchi, Giulia Gerotto, Silvia Gerola, Giuseppe Cossu and Marco Zorzi in Psychological Science

Additional file 4 of LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer

Donatella Delle Cave, Silvia Buonaiuto, Bruno Sainz, Marco Fantuz, Maria Mangini, Alessandro Carrer, Annalisa Di Domenico, Tea Teresa Iavazzo, Gennaro Andolfi, Carme Cortina, Marta Sevillano, Christopher Heeschen, Vincenza Colonna, Marco Corona, Antonio Cucciardi, Martina Di Guida, Eduard Batlle, Annachiara De Luca & Enza Lonardo
Additional file 4: Figure S4. Knockdown of LAMC2 does not affect cell growth. (a) Western blot analysis of LAMC2 in sh empty and LAMC2 knockdown cells. Parallel β-ACTIN immunoblotting was performed. (b) qPCR analysis for LAMC2 and CD44 gene expression in sh empty and LAMC2 knockdown cells. Data are normalized to GAPDH and are presented as fold change in gene expression relative to sh empty. (c) Representative images of sh empty and LAMC2 knockdown cells...

Additional file 6 of LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer

Donatella Delle Cave, Silvia Buonaiuto, Bruno Sainz, Marco Fantuz, Maria Mangini, Alessandro Carrer, Annalisa Di Domenico, Tea Teresa Iavazzo, Gennaro Andolfi, Carme Cortina, Marta Sevillano, Christopher Heeschen, Vincenza Colonna, Marco Corona, Antonio Cucciardi, Martina Di Guida, Eduard Batlle, Annachiara De Luca & Enza Lonardo
Additional file 6: Figure S6. Knockdown of LAMC2 affects tumorigenicity. (a) Representative images from a gelatin degradation assay of sh empty and LAMC2 knockdown cells. Nuclei were stained with Hoechst 33342 (blue), green represents actin (Alexa Fluor™ 488 Phalloidin) and red illustrates gelatin (Rodhamine). The white dashed line circles indicate the areas of degradation. (b) Degradation potential of sh empty and LAMC2 knockdown cells. (c) qPCR analysis for EMT genes in sh empty and LAMC2...

Additional file 10 of LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer

Donatella Delle Cave, Silvia Buonaiuto, Bruno Sainz, Marco Fantuz, Maria Mangini, Alessandro Carrer, Annalisa Di Domenico, Tea Teresa Iavazzo, Gennaro Andolfi, Carme Cortina, Marta Sevillano, Christopher Heeschen, Vincenza Colonna, Marco Corona, Antonio Cucciardi, Martina Di Guida, Eduard Batlle, Annachiara De Luca & Enza Lonardo
Additional file 10: Figure S10. Inhibition of transforming growth factor beta (TGF-β) signaling blocks LAMC2-induced metastasis. (a) Enrichment plots for pancreatic cancer, focal adhesion, hypoxia, MAPK signaling, glycolysis and gluconeogenesis pathways in EGFP+ versus EGFP- cells isolated by FACS from subcutaneous tumors. (b) Western blot analysis for pSMAD2 and SMAD2 in EGFP- versus EGFP+ PANC-1 and #253 cells. Parallel GAPDH immunoblotting was performed. (c) Flow cytometry quantification of EGFP and ALK5-TGFβR1 in EGFP- and EGFP+...

sj-docx-1-dhj-10.1177_20552076221133696 - Supplemental material for A topic trend analysis on COVID-19 literature

Sara Urru, Veronica Sciannameo, Corrado Lanera, Silvano Salaris, Dario Gregori & Paola Berchialla
Supplemental material, sj-docx-1-dhj-10.1177_20552076221133696 for A topic trend analysis on COVID-19 literature by Sara Urru, Veronica Sciannameo, Corrado Lanera, Silvano Salaris, Dario Gregori and Paola Berchialla in Digital Health

Additional file 3 of Unlocking the molecular basis of wheat straw composition and morphological traits through multi-locus GWAS

Salvatore Esposito, Francesca Taranto, Paolo Vitale, Donatella Bianca Maria Ficco, Salvatore Antonio Colecchia, Piergiorgio Stevanato & Pasquale De Vita
Additional file 3: Supplementary Fig. 3. Genotypic variability of the 185wheat genotypes. Loading plot of the first (PC1) and second (PC2) principalcomponents showing the variation among individuals. Based on Triticum ssp.,genotypes are represented by different colored symbols indicated in the legend.

Additional file 1 of Unlocking the molecular basis of wheat straw composition and morphological traits through multi-locus GWAS

Salvatore Esposito, Francesca Taranto, Paolo Vitale, Donatella Bianca Maria Ficco, Salvatore Antonio Colecchia, Piergiorgio Stevanato & Pasquale De Vita
Additional file 1: Supplementary Fig. 1. Frequency distribution of BLUPsfor 15 traits among cultivars. X-axisshow BLUP values while in the y-axisthe frequency is reported.

Additional file 4 of Unlocking the molecular basis of wheat straw composition and morphological traits through multi-locus GWAS

Salvatore Esposito, Francesca Taranto, Paolo Vitale, Donatella Bianca Maria Ficco, Salvatore Antonio Colecchia, Piergiorgio Stevanato & Pasquale De Vita
Additional file 4: Supplementary Fig. 4. Intra-chromosomal LD decaydistance (kb) evaluated considering (A) the whole genome, (B) A genome, (C) Bgenome. Dashed lines indicate the r2 threshold. The intersectionpoint between the decay LD curve and the LD threshold was shown.

Additional file 7 of Unlocking the molecular basis of wheat straw composition and morphological traits through multi-locus GWAS

Salvatore Esposito, Francesca Taranto, Paolo Vitale, Donatella Bianca Maria Ficco, Salvatore Antonio Colecchia, Piergiorgio Stevanato & Pasquale De Vita
Additional file 7: Supplementary Table 1. BLUPs values for the traits under study.

Assessment of socio-relational self-efficacy in breast cancer patients: Italian validation of the social relationship coping efficacy scale (SRCE-I)

Samantha Serpentini, Giulia Silvestri, Antonio Catarinella, Grazia Cristaldi, Caterina Borgese, Giuseppe Deledda, Samuela Sommacal, Letizia Iannopollo, Vincenzo Calvo, Lucia Ronconi & Thomas V. Merluzzi
Abstract Background Social relationship coping efficacy (SRCE) represents the ability to maintain or enhance social relationships in the context of serious illness. The purpose of the current study was to confirm the factor structure, psychometric properties, and utility of the Italian version of the SRCE scale. Methods 181 breast cancer patients completed the SRCE-Italian (SRCE-I), the Cancer Behavior Inventory–Brief/Italian (CBI–B/I), quality of life (QOL) measures (EORTC QLQ-C30; EORTC QLQ-BR23), and the Hospital Anxiety and Depression...

Francigena 8 (2022)

Atlante visuale delle “Ciampate del diavolo”

Adolfo Panarello, Gennaro Farinaro & Paolo Mietto
This supplementary paper provides the complete visual atlas of some of the oldest human footprints (~350 ka) up to now known in the world which are known as “Ciampate del diavolo” or “Devil’s Trails” and are preserved on the Brown Leucitic Tuff created by the Roccamonfina volcano (Tora e Piccilli, Central-Southern Italy). High detailed planimetric maps (1 mm steps), depth maps, oblique quoted views, photographic and light controlled images created from photogrammetric 3D-models give a...

Additional file 1 of Individual differences among older adults with mild and moderate dementia in social and emotional loneliness and their associations with cognitive and psychological functioning

Elena Carbone, Federica Piras, Francesca Ferrari Pellegrini, Paolo Caffarra & Erika Borella
Supplementary Material 1

Multi-tissue RNA-Seq analysis and long-read-based genome assembly reveal complex sex-specific gene regulation and molecular evolution in the Manila clam

Ran Xu, Jacopo Martelossi, Morgan Smits, Mariangela Iannello, Luca Peruzza, Massimiliano Babbucci, Massimo Milan, Joseph P. Dunham, Sophie Breton, Liliana Milani, Sergey V Nuzhdin, Luca Bargelloni, Marco Passamonti & Fabrizio Ghiselli
The genome anntation.

Protecting journalists from harassment: Comparing existing protection mechanisms and the effects on democracy

Alice Baroni, Leen d’Haenens & Wai Han Lo

Past, present and future of chamois science

Luca Corlatti, Laura Iacolina, Toni Safner, Marco Apollonio, Elena Buzan, Francesco Ferretti, Sabine Hammer, Juan Herrero, Luca Rossi, Emmanuel Serrano, Mari Cruz Arnal, Francesca Brivio, Roberta Chirichella, Antonella Cotza, Barbara Crestanello, Johan Espunyes, Daniel Fernández De Luco, Saskia Friedrich, Dragan Gačić, Laura Grassi, Stefano Grignolio, Heidi Hauffe, Kresmir Kavčić, Andreas Kinser, Francesca Lioce … & Nikica Šprem
The chamois Rupicapra spp. is the most abundant mountain ungulate of Europe and the Near East, where it occurs as two species, the Northern chamois R. rupicapra and the Southern chamois R. pyrenaica. Here, we provide a state-of-the-art overview of research trends and the most challenging issues in chamois research and conservation, focusing on taxonomy and systematics, genetics, life history, ecology and behavior, physiology and disease, management, and conservation. Research on Rupicapra has a longstanding...

Additional file 1 of Validity and reliability of a french version of the olfactory disorders questionnaire

Jérôme R. Lechien, Luigi A. Vaira, Serge D. Le Bon, Roxane Geerts, Paolo Boscolo-Rizzo & Sven Saussez
Additional file 1. Appendix 1: The French version of Olfactory Disorder Questionnaire.

Coexisting conditions and concomitant medications do not affect venetoclax management and survival in chronic lymphocytic leukemia

Anna Maria Frustaci, Giovanni Del Poeta, Andrea Visentin, Paolo Sportoletti, Alberto Fresa, Candida Vitale, Roberta Murru, Annalisa Chiarenza, Alessandro Sanna, Francesca Romana Mauro, Gianluigi Reda, Massimo Gentile, Marzia Varettoni, Claudia Baratè, Chiara Borella, Antonino Greco, Marina Deodato, Giulia Zamprogna, Roberta Laureana, Alessandra Cipiciani, Andrea Galitzia, Angelo Curto Pelle, Francesca Morelli, Lucio Malvisi, Marta Coscia … & Alessandra Tedeschi
Background:The question of which parameters may be informative on venetoclax outcome in chronic lymphocytic leukemia (CLL) is still unclear. Furthermore, the choice to treat with venetoclax can be challenging in patients with baseline characteristics or comorbidities that may potentially favor some specific adverse events.Objectives:This study was aimed to evaluate whether age, fitness status, patients’/disease characteristics, or concomitant medications may predict outcomes in CLL patients receiving venetoclax.Design:Retrospective observational study.Methods:Impact of age, presence of Cumulative Illness Rating...

Additional file 9 of LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer

Donatella Delle Cave, Silvia Buonaiuto, Bruno Sainz, Marco Fantuz, Maria Mangini, Alessandro Carrer, Annalisa Di Domenico, Tea Teresa Iavazzo, Gennaro Andolfi, Carme Cortina, Marta Sevillano, Christopher Heeschen, Vincenza Colonna, Marco Corona, Antonio Cucciardi, Martina Di Guida, Eduard Batlle, Annachiara De Luca & Enza Lonardo
Additional file 9: Figure S9. Global gene expression profiles of LAMC2-EGFP+ and EGFP--derived tumors. Heat map of differentially expressed genes in EGFP+ and EGFP- cells isolated from tumors.

Additional file 3 of LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer

Donatella Delle Cave, Silvia Buonaiuto, Bruno Sainz, Marco Fantuz, Maria Mangini, Alessandro Carrer, Annalisa Di Domenico, Tea Teresa Iavazzo, Gennaro Andolfi, Carme Cortina, Marta Sevillano, Christopher Heeschen, Vincenza Colonna, Marco Corona, Antonio Cucciardi, Martina Di Guida, Eduard Batlle, Annachiara De Luca & Enza Lonardo
Additional file 3: Figure S3. LAMC2 expression correlates with CSC content and function. (a) qPCR analysis of LAMC2 gene expression in adherent cells versus spheres. Data are normalized to GAPDH and are presented as fold change in gene expression relative to adherent cells (indicated as Adh). (b) Western blot analysis of LAMC2 in adherent cells versus spheres. Parallel β-ACTIN immunoblotting was performed. (c) qPCR analysis for CD44, CD133 and L1CAM genes in adherent cells versus...

Severe Developmental Dyscalculia Is Characterized by Core Deficits in Both Symbolic and Nonsymbolic Number Sense

Gisella Decarli, Francesco Sella, Silvia Lanfranchi, Giulia Gerotto, Silvia Gerola, Giuseppe Cossu & Marco Zorzi
A long-standing debate concerns whether developmental dyscalculia is characterized by core deficits in processing nonsymbolic or symbolic numerical information as well as the role of domain-general difficulties. Heterogeneity in recruitment and diagnostic criteria make it difficult to disentangle this issue. Here, we selected children (n = 58) with severely compromised mathematical skills (2 SD below average) but average domain-general skills from a large sample referred for clinical assessment of learning disabilities. From the same sample,...

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