Additional file 1: Supporting information including: XRD patterns, TGA-SDTA data and analysis, IRM and DCD data and method, details on Mössbauer spectrometry in high magnetic field, sample MAG3 ZFC and FC hysteresis curves at 5 K.

Additional file 2: Supplementary Table 1. Baseline features of the extension BODI cohort recruited for the analysis of the association between damage accrual and Heath related quality of life (n=147).

Abstract Background It has been suggested that bipolar disorder (BD) is associated with clinical and biological features of accelerated aging. In our previous studies, we showed that long-term lithium treatment was correlated with longer leukocyte telomere length (LTL) in BD patients. A recent study explored the role of TL in BD using patients-derived lymphoblastoid cell lines (LCLs), showing that baseline TL was shorter in BD compared to controls and that lithium in vitro increased TL...

Abstract Background It has been suggested that bipolar disorder (BD) is associated with clinical and biological features of accelerated aging. In our previous studies, we showed that long-term lithium treatment was correlated with longer leukocyte telomere length (LTL) in BD patients. A recent study explored the role of TL in BD using patients-derived lymphoblastoid cell lines (LCLs), showing that baseline TL was shorter in BD compared to controls and that lithium in vitro increased TL...

Abstract Despite modern preparation techniques offer the opportunity to tailor the composition, size, and shape of magnetic nanoparticles, understanding and hence controlling the magnetic properties of such entities remains a challenging task, due to the complex interplay between the volume-related properties and the phenomena occurring at the particle’s surface. The present work investigates spinel iron oxide nanoparticles as a model system to quantitatively analyze the crossover between the bulk and the surface-dominated magnetic regimes. The...

Additional file 2: Figure S2. Stratification of patients by IMDC and Meet-URO scores at nivolumab treatment start (N = 556)*. * Treatment line / patients: 2nd/384, 3rd/118, 4th/41, 5th/11, 6th/1, 7th/1. Abbreviations: PG prognostic group, RG risk group.

Additional file 2: Figure S2. Stratification of patients by IMDC and Meet-URO scores at nivolumab treatment start (N = 556)*. * Treatment line / patients: 2nd/384, 3rd/118, 4th/41, 5th/11, 6th/1, 7th/1. Abbreviations: PG prognostic group, RG risk group.

Additional file 1. Fig. S1 Effect of lithium chloride 1mM for 7 days on telomere length in human-derived neural precursors cells (NPCs). Li: lithium treated; ns: not significant.

Additional file 3: Figure S3. Kaplan Meiers curves showing the prognostic role of nephrectomy in mRCC patients according to the type of nephrectomy.

Abstract Background This study aimed to investigate the trajectory of damage accrual, associated factors, and impact on health-related quality of life (HR-QoL) in a multicenter cohort of patients with Behçet’s syndrome (BS) over 2 years of follow-up. Methods Patients recruited in the BS Overall Damage Index (BODI) validation study were prospectively monitored for 2 years and assessed for damage accrual, defined as an increase ≥1 in the BODI score, and HR-QoL was evaluated by the...

Additional file1: Table S1. Preferred Reporting Items for Systematic review and Meta-Analysis Protocols (PRISMA-P) 2015 checklist: recommended items to address in a systematic review protocol. Table S2. PICOS criteria for inclusion and exclusion of publications. Table S3. Search strategy. Table S4. Detailed information on the data extraction and synthesis. Table S5. Main excluded studies. Table S6. Reported ECMO adverse events in the included studies (n = 32). Table S7. Patient anticoagulation and ECMO characteristics of...

Abstract Background Nephrectomy is considered the backbone of managing patients with localized and selected metastatic renal cell carcinoma (mRCC). The prognostic role of nephrectomy has been widely investigated with cytokines and targeted therapy, but it is still unclear in the immunotherapy era. Methods We investigated the Meet-URO-15 study dataset of 571 pretreated mRCC patients receiving nivolumab as second or further lines about the prognostic role of the previous nephrectomy (received in either the localized or...

Additional file 1: Figure S1. Stratification of patients by IMDC score at disease onset and nivolumab treatment start (N = 493)*. * Missing data for 63 patients. Abbrevviations: PG prognostic group, RG risk group.

Additional file 2: Supplementary Table 1. Baseline features of the extension BODI cohort recruited for the analysis of the association between damage accrual and Heath related quality of life (n=147).

Abstract Background This study aimed to investigate the trajectory of damage accrual, associated factors, and impact on health-related quality of life (HR-QoL) in a multicenter cohort of patients with Behçet’s syndrome (BS) over 2 years of follow-up. Methods Patients recruited in the BS Overall Damage Index (BODI) validation study were prospectively monitored for 2 years and assessed for damage accrual, defined as an increase ≥1 in the BODI score, and HR-QoL was evaluated by the...

Additional file 1. Fig. S1 Effect of lithium chloride 1mM for 7 days on telomere length in human-derived neural precursors cells (NPCs). Li: lithium treated; ns: not significant.

Abstract Despite modern preparation techniques offer the opportunity to tailor the composition, size, and shape of magnetic nanoparticles, understanding and hence controlling the magnetic properties of such entities remains a challenging task, due to the complex interplay between the volume-related properties and the phenomena occurring at the particle’s surface. The present work investigates spinel iron oxide nanoparticles as a model system to quantitatively analyze the crossover between the bulk and the surface-dominated magnetic regimes. The...

Additional file 1: Supporting information including: XRD patterns, TGA-SDTA data and analysis, IRM and DCD data and method, details on Mössbauer spectrometry in high magnetic field, sample MAG3 ZFC and FC hysteresis curves at 5 K.

Abstract Background Nephrectomy is considered the backbone of managing patients with localized and selected metastatic renal cell carcinoma (mRCC). The prognostic role of nephrectomy has been widely investigated with cytokines and targeted therapy, but it is still unclear in the immunotherapy era. Methods We investigated the Meet-URO-15 study dataset of 571 pretreated mRCC patients receiving nivolumab as second or further lines about the prognostic role of the previous nephrectomy (received in either the localized or...

Additional file 1: Figure S1. Stratification of patients by IMDC score at disease onset and nivolumab treatment start (N = 493)*. * Missing data for 63 patients. Abbrevviations: PG prognostic group, RG risk group.

Additional file 3: Figure S3. Kaplan Meiers curves showing the prognostic role of nephrectomy in mRCC patients according to the type of nephrectomy.

Il volume raccoglie gli studi realizzati dall'Università degli Studi di Cagliari nell'ambito dell'accordo di collaborazione sottoscritto con il Ministero della Difesa per la riqualificazione delle aree militari e inaugura la Collana 'Condivisioni', dedicata alle ricerche condotte sul patrimonio difensivo e militare in ambito nazionale e internazionale. In particolare, questo volume, propone l'esito degli approfondimenti e dei progetti esplorativi per il riconoscimento e la valorizzazione del paesaggio militare di Cagliari e dei forti dell'Arcipelago di La...

Additional file 1: Supplementary Figure 1. Flow chart representing the patients’ recruiting process from the BODI validation cohort.

Additional file 1: Supplementary Figure 1. Flow chart representing the patients’ recruiting process from the BODI validation cohort.

Additional file1: Table S1. Preferred Reporting Items for Systematic review and Meta-Analysis Protocols (PRISMA-P) 2015 checklist: recommended items to address in a systematic review protocol. Table S2. PICOS criteria for inclusion and exclusion of publications. Table S3. Search strategy. Table S4. Detailed information on the data extraction and synthesis. Table S5. Main excluded studies. Table S6. Reported ECMO adverse events in the included studies (n = 32). Table S7. Patient anticoagulation and ECMO characteristics of...