1,729 Works

Additional file 5 of Cross-watershed distribution pattern challenging the elimination of Oncomelania hupensis, the intermediate host of Schistosoma japonicum, in Sichuan province, China

Shen Chen, Ding Lu, Lei Duan, Ben Ma, Chao Lv, Yin-long Li, Shen-ning Lu, Lan-hua Li, Liang Xu, Zi-song Wu, Shang Xia, Jing Xu, Yang Liu & Shan Lv
Additional file 5: Figure S4. A Kruskal-Wallis comparison analysis of median distances among different groups.

Cross-watershed distribution pattern challenging the elimination of Oncomelania hupensis, the intermediate host of Schistosoma japonicum, in Sichuan province, China

Shen Chen, Ding Lu, Lei Duan, Ben Ma, Chao Lv, Yin-long Li, Shen-ning Lu, Lan-hua Li, Liang Xu, Zi-song Wu, Shang Xia, Jing Xu, Yang Liu & Shan Lv
Abstract Background Snail control is critical to schistosomiasis control efforts in China. However, re-emergence of Oncomelania hupensis is challenging the achievements of schistosomiasis control. The present study aimed to test whether the amphibious snails can spread across watersheds using a combination of population genetics and geographic statistics. Methods The digital maps and attributes of snail habitats were obtained from the national survey on O. hupensis. Snail sampling was performed in 45 counties of Sichuan Province....

sj-pdf-1-imr-10.1177_03000605221132711 - Supplemental material for New onset atrial fibrillation during orthotopic liver transplantation induced by iced saline injection for transpulmonary thermodilution: a case report

Xin Li, Xu Wang & Zheng Guan
Supplemental material, sj-pdf-1-imr-10.1177_03000605221132711 for New onset atrial fibrillation during orthotopic liver transplantation induced by iced saline injection for transpulmonary thermodilution: a case report by Xin Li, Xu Wang and Zheng Guan in Journal of International Medical Research

Molecular epidemiology and clinical features of hand, foot and mouth disease requiring hospitalization after the use of enterovirus A71 inactivated vaccine in chengdu, China, 2017-2022: a descriptive study

Xiaoxia Duan, Chaoyong Zhang, Xiao Wang, Xueling Ren, Hongxia Peng, Xueqin Tang, Liangzhi Zhang, Zhenhua Chen, Yan Ye, Mengmou Zheng, Wanzhen Zhong, Xiyue Chen, Yilan Zeng, Ping Yuan & Lu Long
Three inactivated enterovirus A71 (EV-A71) vaccines have been widely vaccinated among children in the targeted age group in mainland China since mid-2016. However, comprehensive virological surveillance of hand, foot and mouth disease (HFMD) over multiple years after the use of EV-A71 vaccines has rarely been conducted. Using long-term data extracted from the Public Health and Clinical Center of Chengdu, we described the clinical, aetiological, and epidemiological characteristics of HFMD inpatients after the use of EV-A71...

Additional file 1 of Radiomics features for assessing tumor-infiltrating lymphocytes correlate with molecular traits of triple-negative breast cancer

Guan-Hua Su, Yi Xiao, Lin Jiang, Ren-Cheng Zheng, He Wang, Yan Chen, Ya-Jia Gu, Chao You & Zhi-Ming Shao
Additional file 1: Table S1. Correlation between selected radiomics features and clinical characteristics listed in Table 1. Table S2. Feature categories used in this study. Supplementary Methods. Radiomics features calculation.

New polyacetylenes from Bidens procera

Jinli Tian, Shaohua Yu, Lu Wang, Degang Kong, Wei Zhao, Zhenhua Tian & Honglei Zhou
A phytochemical investigation of Bidens procera L.C.Xu ex X.W.Zheng afforded two novel polyacetylenes, tridecane-2E-monoene-4,6,8-triyntylen-1,13-diol-12-O-β-glucoside (1) and tetradecane-2E,8E-diene-4,6-diyne-1,14-diol-13-O-β-glucoside (2), together with ten known compounds (3 − 12). Their chemical structures were elucidated by NMR and MS spectrums as well as the comparison of the published data. Furthermore, the chemotaxonomy of the yielded compounds was also discussed.

Additional file 1 of Efficacy and evaluation of therapeutic exercises on adults with Parkinson’s disease: a systematic review and network meta-analysis

Yong Yang, Guotuan Wang, Shikun Zhang, Huan Wang, Wensheng Zhou, Feifei Ren, Huimin Liang, Dongdong Wu, Xinying Ji, Makoto Hashimoto & Jianshe Wei
Additional file 1: Appendix 1. PRISMA Checklist. Appendix 2. Protocol. Appendix 3. Search Strategy. Appendix 4. Outcomes. Appendix 5. Definitions of exercise types and non-exercise training control. Appendix 6. Statistical methods in details. Appendix 7. Assessment of the transitivity. Appendix 8. Characteristics of studies and subjects included in the review. Appendix 9. Risk of Bias. Appendix 10. Results from network meta-analyses. Appendix 11. Evaluation of heterogeneity and inconsistency. Appendix 12. Publication bias. Appendix 13. Network...

Additional file 1 of G6PD promotes cell proliferation and dexamethasone resistance in multiple myeloma via increasing anti-oxidant production and activating Wnt/β-catenin pathway

Rui Li, Mengying Ke, Mingming Qi, Zhenru Han, Yuhao Cao, Zhendong Deng, Jinjun Qian, Ye Yang & Chunyan Gu
Additional file 1: Table S1. The clinical characteristics of 70 MM patients.

Additional file 2 of G6PD promotes cell proliferation and dexamethasone resistance in multiple myeloma via increasing anti-oxidant production and activating Wnt/β-catenin pathway

Rui Li, Mengying Ke, Mingming Qi, Zhenru Han, Yuhao Cao, Zhendong Deng, Jinjun Qian, Ye Yang & Chunyan Gu
Additional file 2: Fig S1. Growth curves of ARP1/H929 G6PD-OE/KD cells cultured for 7 days. Fig S2 WB analysis of mTOR and AKT in G6PD-OE/KD cells. Fig. S3 Wnt3a partially restores the suppressed expression of G6PD and β-catenin by RRX-001.

The ROS/NF-κB/HK2 axis is involved in the arsenic-induced Warburg effect in human L-02 hepatocytes

Fanshuo Yin, Ying Zhang, Xin Zhang, Meichen Zhang, Zaihong Zhang, Yunyi Yin, Haili Xu, Yanmei Yang & Yanhui Gao
Arsenic has been identified as a carcinogen, although the molecular mechanism underlying itscarcinogenesis has not been fully elucidated. To date, only a few studies have attempted to confirm a direct link between oxidative stress and the Warburg effect . This study demonstrated that 0.2 μmol/L As3+ induced the Warburg effect to contribute to abnormal proliferation of L-02 cells, that was mediated by upregulation of hexokinase 2 (HK2), a key enzyme in glycolysis. Further study indicated...

Additional file 3 of CASA: a comprehensive database resource for the COVID-19 Alternative Splicing Atlas

Yaxin Chen, Gang Wang, Jingyi Li, Lei Xia, Lin Zhu, Wenxing Li, Qiang Luo, Yinlu Liao, Yao Lin, Liyun Bi, Hubin Chen, Jiemei Chu, Yueqi Li, Jinming Su, Li Ye, Jun-jun Jiang, Hao Liang, Weimin Li & Sanqi An
Additional file 3: Figure S1. The landscape of samples and AS events in CASA. (A) The number of samples in each body site. (B) Proportion of different splicing types in CASA. (C-D) The number and distribution of different splicing types across body sites.

Integrated physiological and transcriptional dissection reveals the core genes involving nutrient transport and osmoregulatory substance biosynthesis in allohexaploid wheat seedlings under salt stress

Jun-fan Chen, Ying Liu, Tian-yu Zhang, Zheng-fu Zhou, Jin-yong Huang, Ting Zhou & Ying-peng Hua
Abstract Background Soil salinization has become a global problem restricting the seed yield and quality of crops, including wheat (Triticum aestivum L.). Salinity significantly alters plant morphology and severely disrupts physiological homeostasis. Salt tolerance of wheat has been widely studied whereas core ion transporters responsive to salt stress remain elusive. Results In this study, the wheat seedlings were subjected to salinity toxicity for morpho-physiological and transcriptomic analysis of wheat salt tolerance. There was a inversely...

Additional file 1 of Integrated physiological and transcriptional dissection reveals the core genes involving nutrient transport and osmoregulatory substance biosynthesis in allohexaploid wheat seedlings under salt stress

Jun-fan Chen, Ying Liu, Tian-yu Zhang, Zheng-fu Zhou, Jin-yong Huang, Ting Zhou & Ying-peng Hua
Additional file 1: Supplementary Table S1. Overview of the transcriptome sequencing data in this study. SupplementaryFigure S1. Expression correlation of in shoot and root samples ofwheat plants under salt stress. After7 d of wheat seed germination, the wheat seedlings were transferred to asolution containing 100 mM NaCl for 10 d. The heatmap showed the FPKM values ofgenes. SupplementaryFigure S2. The primary metabolic pathway enrichment map of DEGs inthe shoots of wheat plants under salt stress....

Additional file 1 of Integrated physiological and transcriptional dissection reveals the core genes involving nutrient transport and osmoregulatory substance biosynthesis in allohexaploid wheat seedlings under salt stress

Jun-fan Chen, Ying Liu, Tian-yu Zhang, Zheng-fu Zhou, Jin-yong Huang, Ting Zhou & Ying-peng Hua
Additional file 1: Supplementary Table S1. Overview of the transcriptome sequencing data in this study. SupplementaryFigure S1. Expression correlation of in shoot and root samples ofwheat plants under salt stress. After7 d of wheat seed germination, the wheat seedlings were transferred to asolution containing 100 mM NaCl for 10 d. The heatmap showed the FPKM values ofgenes. SupplementaryFigure S2. The primary metabolic pathway enrichment map of DEGs inthe shoots of wheat plants under salt stress....

Transcriptome profile reveals novel candidate genes associated with bone strength in end-of-lay hens

Qiaoxian Yue, Ye Chen, Hui Chen & Rongyan Zhou
Bone weakness causes many problems such as osteoporosis, bone fractures, and economic loss, especially at the late stage of lay, in laying hen production. However, the genetic factors and molecular mechanism affecting the bone strength is still largely unknown. To elucidate the molecular mechanism and genetic factors affecting bone strength, a total of six cDNA libraries were constructed and used to compare genetic differences between tibia with higher(Group HBS)and lower(Group LBS)breaking strength in Hyline grey...

Realizing recrystallization-stabilization temperature range inversion in high Mg content Al alloys via pulsed electric current

Zhen Zhang, Di Zhang, Hao Gong, Xinfang Zhang & Jishan Zhang
A longstanding challenge with high Mg content Al alloys is the trade-off between corrosion resistance and strength, because the stabilization temperature is lower than the recrystallization temperature corresponding to a no stabilization temperature range. Herein, a stabilization temperature range is found with an excellent match of strength and corrosion resistance of high Mg content Al alloy via pulsed electric current. The stimulated atomic diffusion rate resulted in discontinuous grain boundary precipitates, along with a lower...

Supplementary document for Al2O3-YAG:Ce/YAG composite phosphor ceramics in transmissive configuration for high-brightness laser-driven lighting - 6096772.pdf

Pengfei Sang, Le Zhang, Jian Kang, yanbin li, shiwei chen, peng yang, Bingheng Sun, Yang Li & Hao Chen
Supplemental Document (revised)

Additional file 6 of ELOVL gene family plays a virtual role in response to breeding selection and lipid deposition in different tissues in chicken (Gallus gallus)

Dandan Wang, Xinyan Li, Panpan Zhang, Yuzhu Cao, Ke Zhang, Panpan Qin, Yulong Guo, Zhuanjian Li, Yadong Tian, Xiangtao Kang, Xiaojun Liu & Hong Li
Additional file 6: Table S4. List of lipids in intramuscular fat correlated with ELOVL3 expression in pectorals.

Additional file 7 of ELOVL gene family plays a virtual role in response to breeding selection and lipid deposition in different tissues in chicken (Gallus gallus)

Dandan Wang, Xinyan Li, Panpan Zhang, Yuzhu Cao, Ke Zhang, Panpan Qin, Yulong Guo, Zhuanjian Li, Yadong Tian, Xiangtao Kang, Xiaojun Liu & Hong Li
Additional file 7: Table S5. Data sources for red jungle fowl and layers used in this study.

Additional file 7 of ELOVL gene family plays a virtual role in response to breeding selection and lipid deposition in different tissues in chicken (Gallus gallus)

Dandan Wang, Xinyan Li, Panpan Zhang, Yuzhu Cao, Ke Zhang, Panpan Qin, Yulong Guo, Zhuanjian Li, Yadong Tian, Xiangtao Kang, Xiaojun Liu & Hong Li
Additional file 7: Table S5. Data sources for red jungle fowl and layers used in this study.

Additional file 1 of ELOVL gene family plays a virtual role in response to breeding selection and lipid deposition in different tissues in chicken (Gallus gallus)

Dandan Wang, Xinyan Li, Panpan Zhang, Yuzhu Cao, Ke Zhang, Panpan Qin, Yulong Guo, Zhuanjian Li, Yadong Tian, Xiangtao Kang, Xiaojun Liu & Hong Li
Additional file 1: Table S1. Association analysis of 51 SNPs in the ELOVL gene family with growth, carcass and meat quality traits in Gushi ×Anka F2 chickens.

Additional file 4 of ELOVL gene family plays a virtual role in response to breeding selection and lipid deposition in different tissues in chicken (Gallus gallus)

Dandan Wang, Xinyan Li, Panpan Zhang, Yuzhu Cao, Ke Zhang, Panpan Qin, Yulong Guo, Zhuanjian Li, Yadong Tian, Xiangtao Kang, Xiaojun Liu & Hong Li
Additional file 4: Table S3. Putative ERE and AP1 element in chicken ELOVL genes promoter.

Additional file 5 of ELOVL gene family plays a virtual role in response to breeding selection and lipid deposition in different tissues in chicken (Gallus gallus)

Dandan Wang, Xinyan Li, Panpan Zhang, Yuzhu Cao, Ke Zhang, Panpan Qin, Yulong Guo, Zhuanjian Li, Yadong Tian, Xiangtao Kang, Xiaojun Liu & Hong Li
Additional file 5: Figure S2. The expression levels of ELOVL genes in hypothalamus, liver, abdominal fat and pectorals of AFL and AFH.

Deep learning approach for cancer subtype classification using high-dimensional gene expression data

Jiquan Shen, Jiawei Shi, Junwei Luo, Haixia Zhai, Xiaoyan Liu, Zhengjiang Wu, Chaokun Yan & Huimin Luo
Abstract Motivation Studies have shown that classifying cancer subtypes can provide valuable information for a range of cancer research, from aetiology and tumour biology to prognosis and personalized treatment. Current methods usually adopt gene expression data to perform cancer subtype classification. However, cancer samples are scarce, and the high-dimensional features of their gene expression data are too sparse to allow most methods to achieve desirable classification results. Results In this paper, we propose a deep...

Additional file 1 of ELOVL gene family plays a virtual role in response to breeding selection and lipid deposition in different tissues in chicken (Gallus gallus)

Dandan Wang, Xinyan Li, Panpan Zhang, Yuzhu Cao, Ke Zhang, Panpan Qin, Yulong Guo, Zhuanjian Li, Yadong Tian, Xiangtao Kang, Xiaojun Liu & Hong Li
Additional file 1: Table S1. Association analysis of 51 SNPs in the ELOVL gene family with growth, carcass and meat quality traits in Gushi ×Anka F2 chickens.

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