1,729 Works

Additional file 5 of ELOVL gene family plays a virtual role in response to breeding selection and lipid deposition in different tissues in chicken (Gallus gallus)

Dandan Wang, Xinyan Li, Panpan Zhang, Yuzhu Cao, Ke Zhang, Panpan Qin, Yulong Guo, Zhuanjian Li, Yadong Tian, Xiangtao Kang, Xiaojun Liu & Hong Li
Additional file 5: Figure S2. The expression levels of ELOVL genes in hypothalamus, liver, abdominal fat and pectorals of AFL and AFH.

Additional file 6 of ELOVL gene family plays a virtual role in response to breeding selection and lipid deposition in different tissues in chicken (Gallus gallus)

Dandan Wang, Xinyan Li, Panpan Zhang, Yuzhu Cao, Ke Zhang, Panpan Qin, Yulong Guo, Zhuanjian Li, Yadong Tian, Xiangtao Kang, Xiaojun Liu & Hong Li
Additional file 6: Table S4. List of lipids in intramuscular fat correlated with ELOVL3 expression in pectorals.

Additional file 7 of ELOVL gene family plays a virtual role in response to breeding selection and lipid deposition in different tissues in chicken (Gallus gallus)

Dandan Wang, Xinyan Li, Panpan Zhang, Yuzhu Cao, Ke Zhang, Panpan Qin, Yulong Guo, Zhuanjian Li, Yadong Tian, Xiangtao Kang, Xiaojun Liu & Hong Li
Additional file 7: Table S5. Data sources for red jungle fowl and layers used in this study.

Additional file 7 of ELOVL gene family plays a virtual role in response to breeding selection and lipid deposition in different tissues in chicken (Gallus gallus)

Dandan Wang, Xinyan Li, Panpan Zhang, Yuzhu Cao, Ke Zhang, Panpan Qin, Yulong Guo, Zhuanjian Li, Yadong Tian, Xiangtao Kang, Xiaojun Liu & Hong Li
Additional file 7: Table S5. Data sources for red jungle fowl and layers used in this study.

Additional file 3 of The effect of SNPs in lncRNA as ceRNA on the risk and prognosis of hepatocellular carcinoma

Han Mo, Xi Wang, Guohua Ji, Xiao Liang, Yi Yang, Wenjing Sun, Xueyuan Jia, Lidan Xu, Yuandong Qiao, Henan Zhou, Wenhui Zhao, Songbin Fu & Xuelong Zhang
Additional file 3:

Additional file 1 of Change lifestyle modification plan/transtheoretical model in non-alcoholic simple fatty liver disease: a pilot randomized study

Lijuan Li, Kun Hou, Mengya Yuan, Yan Zhang & Yang Zhang
Supplementary Material 1. Supplementary Table 1. Transtheoretical Model and stages of change-oriented lifestyle intervention strategies and measures for simple fatty liver disease patients. Supplementary Table 2. Comparison of healthy behavior levels of the 2 groups (controls vs. transtheoretical model and stages of change) before and after intervention.

Additional file 1 of CXCL1/CXCR2 is involved in white matter injury in neonatal rats via the gut–brain axis

Can Yang, Zhiyuan Feng, Hong Deng, Lu Dai, Ling He, Linlin Yin & Jing Zhao
Additional file 1: Figure S1. WB raw data of Figure 2A.

Is regular in-person recall superior to non-regular in-person recall in clinical outcomes among new patients undergoing peritoneal dialysis

Ying Liu, Wen Xiu Chang, Ben-Chung Cheng & Jin-Bor Chen
To investigate the different impacts on clinical outcomes between regular recall and non-regular recall among incident peritoneal dialysis (PD) patients. A two-center cohort of 216 new PD patients from 1January 2013, to 31 December 2014, was studied. Informative clinical data were collected from baseline until two years after PD initiation, including demographics, laboratory and PD-related parameters, PD-related peritonitis rates, and frequency of hospitalization. Regular in-person recall (RPR) was defined as having a one-month interval and...

Additional file 1 of Identification of the cuproptosis-related molecular subtypes and an immunotherapy prognostic model in hepatocellular carcinoma

Li Zhang, Jingwei Xu, Xiufeng Chu, Hongqiao Zhang, Xueyuan Yao, Jian Zhang & Yanwei Guo
Additional file1. Fig S1: The flow chart of this study. HCC, hepatocellular carcinoma. TMB, tumor mutation burden. TME, tumor microenvironment. GSVA, gene set variation analysis. GO, Gene Ontology. KEGG, Kyoto Encyclopedia.

Additional file 1 of A dual deep neural network for auto-delineation in cervical cancer radiotherapy with clinical validation

Shihong Nie, Yuanfeng Wei, Fen Zhao, Ya Dong, Yan Chen, Qiaoqi Li, Wei Du, Xin Li, Xi Yang & Zhiping Li
Additional file 1. Supplemental methods, tables, and figures.

A dual deep neural network for auto-delineation in cervical cancer radiotherapy with clinical validation

Shihong Nie, Yuanfeng Wei, Fen Zhao, Ya Dong, Yan Chen, Qiaoqi Li, Wei Du, Xin Li, Xi Yang & Zhiping Li
Abstract Background Artificial intelligence (AI) algorithms are capable of automatically detecting contouring boundaries in medical images. However, the algorithms impact on clinical practice of cervical cancer are unclear. We aimed to develop an AI-assisted system for automatic contouring of the clinical target volume (CTV) and organs-at-risk (OARs) in cervical cancer radiotherapy and conduct clinical-based observations. Methods We first retrospectively collected data of 203 patients with cervical cancer from West China Hospital. The proposed method named...

Appenidx S1 Data sources for compiling distribution data from Preserving the woody plant tree of life in China under future climate and land-cover changes

Shijia Peng, Ruocheng Hu, Santiago José Elías Velazco, Yuan Luo, Tong Lyu, Xiaoling Zhang, Jian Zhang & Zhiheng Wang
The tree of life (TOL) is severely threatened by climate and land-cover changes. Preserving the TOL is urgent, but has not been included in the post-2020 global biodiversity framework. Protected areas (PAs) are fundamental for biological conservation. However, we know little about the effectiveness of existing PAs in preserving the TOL of plants and how to prioritize PA expansion for better TOL preservation under future climate and land-cover changes. Here, using high-resolution distribution maps of...

Appenidx S3 Supplementary Figures from Preserving the woody plant tree of life in China under future climate and land-cover changes

Shijia Peng, Ruocheng Hu, Santiago José Elías Velazco, Yuan Luo, Tong Lyu, Xiaoling Zhang, Jian Zhang & Zhiheng Wang
The tree of life (TOL) is severely threatened by climate and land-cover changes. Preserving the TOL is urgent, but has not been included in the post-2020 global biodiversity framework. Protected areas (PAs) are fundamental for biological conservation. However, we know little about the effectiveness of existing PAs in preserving the TOL of plants and how to prioritize PA expansion for better TOL preservation under future climate and land-cover changes. Here, using high-resolution distribution maps of...

Appenidx S3 Supplementary Figures from Preserving the woody plant tree of life in China under future climate and land-cover changes

Shijia Peng, Ruocheng Hu, Santiago José Elías Velazco, Yuan Luo, Tong Lyu, Xiaoling Zhang, Jian Zhang & Zhiheng Wang
The tree of life (TOL) is severely threatened by climate and land-cover changes. Preserving the TOL is urgent, but has not been included in the post-2020 global biodiversity framework. Protected areas (PAs) are fundamental for biological conservation. However, we know little about the effectiveness of existing PAs in preserving the TOL of plants and how to prioritize PA expansion for better TOL preservation under future climate and land-cover changes. Here, using high-resolution distribution maps of...

Fecal microbiota transplantation combined with ruxolitinib as a salvage treatment for intestinal steroid-refractory acute GVHD

Yin Liu, Ye Zhao, Jiaqian Qi, Xiao Ma, Xiaofei Qi, Depei Wu & Yang Xu
Abstract Acute graft-versus-host disease (aGVHD), especially intestinal aGVHD, is one of the most severe complications after allogeneic hematopoietic stem cell transplantation (HSCT). Fecal microbiota transplantation (FMT) has been applied to the treatment of intestinal steroid-refractory aGVHD (SR-aGVHD). Ruxolitinib is the first drug recommended for SR-aGVHD. Here, we reported the outcome data from 21 patients who had received the combined treatment of FMT with ruxolitinib as a salvage treatment in intestinal SR-aGVHD after HSCT. The overall...

Additional file 1 of The predictive effect of direct-indirect bilirubin ratio on clinical events in acute coronary syndrome: results from an observational cohort study in north China

Jiayu Li, Yanguo Xin, Jingye Li, Meng Meng, Li Zhou, Hui Qiu, Hui Chen & Hongwei Li
Supplementary Material 1: Extreme high-risk ASCVD

Additional file 2 of The predictive effect of direct-indirect bilirubin ratio on clinical events in acute coronary syndrome: results from an observational cohort study in north China

Jiayu Li, Yanguo Xin, Jingye Li, Meng Meng, Li Zhou, Hui Qiu, Hui Chen & Hongwei Li
Supplementary Material 2: Z test of AUCs in Figure 2

Additional file 2 of The predictive effect of direct-indirect bilirubin ratio on clinical events in acute coronary syndrome: results from an observational cohort study in north China

Jiayu Li, Yanguo Xin, Jingye Li, Meng Meng, Li Zhou, Hui Qiu, Hui Chen & Hongwei Li
Supplementary Material 2: Z test of AUCs in Figure 2

The predictive effect of direct-indirect bilirubin ratio on clinical events in acute coronary syndrome: results from an observational cohort study in north China

Jiayu Li, Yanguo Xin, Jingye Li, Meng Meng, Li Zhou, Hui Qiu, Hui Chen & Hongwei Li
Abstract Background: Patients with extremely high-risk ASCVD usually suffered poor prognosis, bilirubin is considered closely related to cardiovascular outcomes. However, there is controversy over the relationship between bilirubin and coronary artery disease. This study aimed to evaluate the predictive value of the DIBIL ratio in patients with extremely high-risk ASCVD. Methods: 10,260 consecutive patients with extremely high-risk ASCVD were enrolled in this study. All patients were divided into three groups according to their DIBIL ratio....

Additional file 1 of Age- and sex-specific reference values of biventricular strain and strain rate derived from a large cohort of healthy Chinese adults: a cardiovascular magnetic resonance feature tracking study

Gengxiao Li, Zhen Zhang, Yiyuan Gao, Chengcheng Zhu, Shanshan Zhou, Lizhen Cao, Zhiwei Zhao, Jun Zhao, Karen Ordovas, Mingwu Lou, Kuncheng Li & Gerald M. Pohost
Additional file 1: Fig. S1. Example of biventricular myocardial deformation analysis by Medis (Medis Medical Imaging, Leiden, the Netherlands). Contours are illustrated in LV endocardial and epicardial borders in short-axis view (a), four-chamber view (b), three-chamber view (c), and two-chamber view (d), and RV endocardial in four-chamber view (e).

Additional file 2 of Age- and sex-specific reference values of biventricular strain and strain rate derived from a large cohort of healthy Chinese adults: a cardiovascular magnetic resonance feature tracking study

Gengxiao Li, Zhen Zhang, Yiyuan Gao, Chengcheng Zhu, Shanshan Zhou, Lizhen Cao, Zhiwei Zhao, Jun Zhao, Karen Ordovas, Mingwu Lou, Kuncheng Li & Gerald M. Pohost
Additional file 2: Fig. S2. Correlation between biventricular global strain and age assessed by Medis. Linear regressions with the 95% prediction band for LV global radial strain (GRS) (a), global circumferential strain (GCS) (b), global longitudinal strain (GLS) (c), and RV free wall- global longitudinal strain (RVFW-GLS) (d).

clusterMLD: An Efficient Hierarchical Clustering Method for Multivariate Longitudinal Data

Junyi Zhou, Ying Zhang & Wanzhu Tu
Longitudinal data clustering is challenging because the grouping has to account for the similarity of individual trajectories in the presence of sparse and irregular times of observation. This paper puts forward a hierarchical agglomerative clustering method based on a dissimilarity metric that quantifies the cost of merging two distinct groups of curves, which are depicted by B-splines for the repeatedly measured data. Extensive simulations show that the proposed method has superior performance in determining the...

clusterMLD: An Efficient Hierarchical Clustering Method for Multivariate Longitudinal Data

Junyi Zhou, Ying Zhang & Wanzhu Tu
Longitudinal data clustering is challenging because the grouping has to account for the similarity of individual trajectories in the presence of sparse and irregular times of observation. This paper puts forward a hierarchical agglomerative clustering method based on a dissimilarity metric that quantifies the cost of merging two distinct groups of curves, which are depicted by B-splines for the repeatedly measured data. Extensive simulations show that the proposed method has superior performance in determining the...

Additional file 2 of Effective-component compatibility of Bufei Yishen formula III ameliorated COPD by improving airway epithelial cell senescence by promoting mitophagy via the NRF2/PINK1 pathway

Min-yan Li, Yan-qin Qin, Yan-ge Tian, Kang-chen Li, Brian G. Oliver, Xue-fang Liu, Peng Zhao & Jian-sheng Li
Additional file 2.

Additional file 2 of Effective-component compatibility of Bufei Yishen formula III ameliorated COPD by improving airway epithelial cell senescence by promoting mitophagy via the NRF2/PINK1 pathway

Min-yan Li, Yan-qin Qin, Yan-ge Tian, Kang-chen Li, Brian G. Oliver, Xue-fang Liu, Peng Zhao & Jian-sheng Li
Additional file 2.

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