2 Works
Temperature-sensitive heparin-modified poloxamer hydrogel with affinity to KGF facilitate the morphologic and functional recovery of the injured rat uterus
He-Lin Xu, Jie Xu, Si-Si Zhang, Qun-Yan Zhu, Bing-Hui Jin, De-Li ZhuGe, Bi-Xin Shen, Xue-Qing Wu, Jian Xiao & Ying-Zheng Zhao
Endometrial injury usually results in intrauterine adhesion (IUA), which is an important cause of infertility and recurrent miscarriage in reproductive women. There is still lack of an effective therapeutic strategy to prevent occurrence of IUA. Keratinocyte growth factor (KGF) is a potent repair factor for epithelial tissues. Here, a temperature-sensitive heparin-modified poloxamer (HP) hydrogel with affinity to KGF (KGF-HP) was used as a support matrix to prevent IUA and deliver KGF. The rheology of KGF-HP...
Temperature-sensitive heparin-modified poloxamer hydrogel with affinity to KGF facilitate the morphologic and functional recovery of the injured rat uterus
He-Lin Xu, Jie Xu, Si-Si Zhang, Qun-Yan Zhu, Bing-Hui Jin, De-Li ZhuGe, Bi-Xin Shen, Xue-Qing Wu, Jian Xiao & Ying-Zheng Zhao
Endometrial injury usually results in intrauterine adhesion (IUA), which is an important cause of infertility and recurrent miscarriage in reproductive women. There is still lack of an effective therapeutic strategy to prevent occurrence of IUA. Keratinocyte growth factor (KGF) is a potent repair factor for epithelial tissues. Here, a temperature-sensitive heparin-modified poloxamer (HP) hydrogel with affinity to KGF (KGF-HP) was used as a support matrix to prevent IUA and deliver KGF. The rheology of KGF-HP...
Affiliations
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Beijing Tian Tan Hospital2
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Sixth Affiliated Hospital of Sun Yat-sen University2
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Central South University2
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Zunyi Medical University2
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Key Laboratory of Guangdong Province2
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Fudan University2
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Capital Medical University2
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Chongqing Medical University2
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Qiqihar Medical University2
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Shanghai Jiao Tong University2