5,306 Works

Additional file 1 of Comparison of response evaluation criteria in solid tumors and tumor regression grade in evaluating the effect of preoperative systemic therapy of gastric cancer

Ming-Yu Lai, Shi-Yang Kang, Yu-Ting Sun, Ting-Ting Quan, Shi-Xun Lu, Cai-Yun He, Zhi-Wei Zhou, Li-Qiong Yang, Hui-Yan Luo, Feng-Hua Wang, Yu-Hong Li, Rui-Hua Xu, Wen-Long Guan & Miao-Zhen Qiu
Additional file 1.

Additional file 3 of Comparison of response evaluation criteria in solid tumors and tumor regression grade in evaluating the effect of preoperative systemic therapy of gastric cancer

Ming-Yu Lai, Shi-Yang Kang, Yu-Ting Sun, Ting-Ting Quan, Shi-Xun Lu, Cai-Yun He, Zhi-Wei Zhou, Li-Qiong Yang, Hui-Yan Luo, Feng-Hua Wang, Yu-Hong Li, Rui-Hua Xu, Wen-Long Guan & Miao-Zhen Qiu
Additional file 3.

Additional file 4 of Comparison of response evaluation criteria in solid tumors and tumor regression grade in evaluating the effect of preoperative systemic therapy of gastric cancer

Ming-Yu Lai, Shi-Yang Kang, Yu-Ting Sun, Ting-Ting Quan, Shi-Xun Lu, Cai-Yun He, Zhi-Wei Zhou, Li-Qiong Yang, Hui-Yan Luo, Feng-Hua Wang, Yu-Hong Li, Rui-Hua Xu, Wen-Long Guan & Miao-Zhen Qiu
Additional file 4.

Additional file 6 of Comparison of response evaluation criteria in solid tumors and tumor regression grade in evaluating the effect of preoperative systemic therapy of gastric cancer

Ming-Yu Lai, Shi-Yang Kang, Yu-Ting Sun, Ting-Ting Quan, Shi-Xun Lu, Cai-Yun He, Zhi-Wei Zhou, Li-Qiong Yang, Hui-Yan Luo, Feng-Hua Wang, Yu-Hong Li, Rui-Hua Xu, Wen-Long Guan & Miao-Zhen Qiu
Additional file 6.

The diversity and evolutionary relationships of ticks and tick-borne bacteria collected in China

JunHua Tian, Xin Hou, MiHong Ge, HongBin Xu, Bin Yu, Jing Liu, RenFu Shao, Edward C. Holmes, ChaoLiang Lei & Mang Shi
Abstract Background Ticks (order Ixodida) are ectoparasites, vectors and reservoirs of many infectious agents affecting humans and domestic animals. However, the lack of information on tick genomic diversity leaves significant gaps in the understanding of the evolution of ticks and associated bacteria. Results We collected > 20,000 contemporary and historical (up to 60 years of preservation) tick samples representing a wide range of tick biodiversity across diverse geographic regions in China. Metagenomic sequencing was performed...

Additional file 11 of Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 11. Summary statistics for the differential expression analysis. DE: differentially expressed. LS: lateral septum, MPOA: medial preoptic area, NAc: nucleus accumbens.

Additional file 12 of Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 12. Volcano plots for the differential expression analysis. These plots depict the log2 fold-change (x-axis) against the -log10 of the uncorrected p-value (y-axis) for each gene in each pairwise comparison in the medial preoptic area (MPOA, A), nucleus accumbens (NAc, B), and lateral septum (LS, C). Differentially expressed genes are depicted in red.

Additional file 13 of Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 13. Functional enrichment of genes differentially expressed in the medial preoptic area (MPOA). For each pairwise comparison, the functional enrichments in gene ontologies of the biological processes (A), cellular components (B), and molecular functions (C) categories were tested for the differentially expressed genes up- or down-regulated (UP, and DOWN, respectively). The labels of pairwise comparisons were coded in two letters: the first one represents the phenotype (M: mothers, F: fathers, P: paternal males,...

Additional file 17 of Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 17. Functional enrichment of genes differentially expressed in the nucleus accumbens (NAc). For each pairwise comparison, the functional enrichments in gene ontologies of the biological processes (A), cellular components (B), and molecular functions (C) categories as well as in pathways from the Kyoto Encyclopedia of Genes and Genomes (KEGG, D) were tested for the differentially expressed genes up- or down-regulated (UP, and DOWN, respectively). The labels of pairwise comparisons were coded in two...

Additional file 18 of Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 18. Functional enrichment of genes differentially expressed in the lateral septum (LS). For each pairwise comparison, the functional enrichments in gene ontologies of the biological processes (A), cellular components (B), and molecular functions (C) categories as well as in pathways from the Kyoto Encyclopedia of Genes and Genomes (KEGG, D) were tested for the differentially expressed genes up- or down-regulated (UP, and DOWN, respectively). The labels of pairwise comparisons were coded in two...

Additional file 18 of Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 18. Functional enrichment of genes differentially expressed in the lateral septum (LS). For each pairwise comparison, the functional enrichments in gene ontologies of the biological processes (A), cellular components (B), and molecular functions (C) categories as well as in pathways from the Kyoto Encyclopedia of Genes and Genomes (KEGG, D) were tested for the differentially expressed genes up- or down-regulated (UP, and DOWN, respectively). The labels of pairwise comparisons were coded in two...

Additional file 1 of Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 1. Time spent in each behavior during the parental behavior test. The total duration across the entire test session is depicted for each animal for the autogrooming, carry, huddling, licking & grooming, locomotion, nest building, and sniffing behaviors; each data point thus represents a distinct animal. The horizontal line in the shaded violin represents the 50% quantile of the density estimate.

Additional file 19 of Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 19. Estimated cell type proportions. The proportions of various cell types were estimated in our dataset using a publicly-available single-cell RNA sequencing dataset. While panel (A) shows the estimated proportions for all genes detected in our study, panels (B) and (C) depict the estimated proportion of the “Astrocytes” and “Neurons” cell types, or only “Neurons”, respectively, in genes differentially expressed in the given structure.

Additional file 3 of Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 3. Behavioral bouts analysis. For each behavior scored, the duration of each bout was summarized by mean or median across the entire parental behavior test for each animal. Each data point represents a distinct animal, and the boxplots depict the median (thick horizontal line) and the 25th and 75th percentiles.

Additional file 2 of Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 2. Analysis of variance (ANOVA) results for all behaviors scored during the parental behavior test.

Additional file 26 of Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 26. Functional enrichment of gene ontologies of the molecular functions category in gene co-expression modules derived from the weighted gene coexpression network analysis (WGCNA).

Additional file 28 of Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 28. Representative location of tissue punches collection. As no atlas in stereotaxic coordinates exists for the prairie vole brain, representative plates from the rat brain atlas [95] are depicted. Tissue punches were taken from sections ranging from plates 12–18 for the nucleus accumbens (NAc, A), plates 19–27 for the lateral septum (LS, B), and plates 32–40 for the medial preoptic area (MPOA, C).

Additional file 1 of YAP1 protects against septic liver injury via ferroptosis resistance

Jin Wang, Qian Zhu, Rui Li, Jing Zhang, Xujun Ye & Xinyi Li
Additional file 1. Supplementary figures.

Additional file 9 of Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 9. Functional enrichment across structures and phenotypes. For each pairwise comparison, the functional enrichments in gene ontologies of the biological processes (BP), cellular components (CC), and molecular functions (MF) categories as well as in pathways from the Kyoto Encyclopedia of Genes and Genomes (KEGG) were tested for the differentially expressed genes up- or down-regulated (UP, and DOWN, respectively). The labels of pairwise comparisons were coded in two letters: the first one represents the...

Additional file 7 of Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 7. Detailed results from the linear regressions between all behaviors scored during the parental behaviors test, testing for an interaction of Group (Mothers/Fathers/Paternal).

Experimental study on the seismic behavior of RC columns improved with central large-diameter butted steel rods

Hanming Zhang, Jie Luo, Jianchun Xiao, Jing Chen, Zhuoqun Liu, Yi Zhang, Zongli Luo & Hong Zhang
Abstract A reinforced concrete (RC) column improved with central large-diameter butted steel rods (CLBSR column) has been proposed to increase the limit value of the axial compression ratio. This paper presents the seismic behavior analysis of CLBSR columns subjected to low-cycle reciprocating loading. The CLBSR columns were also compared with the RC column improved with central large-diameter steel rods (CLSR column) and the RC column improved with central reinforcement bars (CRB column) under the same...

Experimental study on the seismic behavior of RC columns improved with central large-diameter butted steel rods

Hanming Zhang, Jie Luo, Jianchun Xiao, Jing Chen, Zhuoqun Liu, Yi Zhang, Zongli Luo & Hong Zhang
Abstract A reinforced concrete (RC) column improved with central large-diameter butted steel rods (CLBSR column) has been proposed to increase the limit value of the axial compression ratio. This paper presents the seismic behavior analysis of CLBSR columns subjected to low-cycle reciprocating loading. The CLBSR columns were also compared with the RC column improved with central large-diameter steel rods (CLSR column) and the RC column improved with central reinforcement bars (CRB column) under the same...

Constructing new acid-activated anticancer peptide by attaching a desirable anionic binding partner peptide

Yun Zhang, Linlin Chang, Hexin Bao, Xiaoyan Wu, Hui Liu, Sanhu Gou, Jingying Zhang & Jingman Ni
Improving the cell selectivity of anticancer peptides (ACPs) is a major hurdle in their clinical utilisation. In this study, a new acid-activated ACP was designed by conjugating a cationic ACP LK to its anionic binding partner peptide (LEH) via a disulphide linker to trigger antitumor activity at acidic pH while masking its killing activity at normal pH. Three anionic binding peptides containing different numbers of glutamic acid (Glu) and histidine were engineered to obtain an...

Additional file 2 of SPARC plays an important role in the oviposition and nymphal development in Nilaparvata lugens Stål

Weixia Wang, Tingheng Zhu, Pinjun Wan, Qi Wei, Jiachun He, Fengxiang Lai & Qiang Fu
Additional file 2: Figure. S1. Unrooted phylogenetic tree of NlSPARC from N.lugens and representative insect species. An unrooted phylogenetic tree was constructed by the neighbour-joining tree construction program Mega 7. Evolutionary distances were computed using Poisson correction method. Branch support values (1000 bootstraps) for nodes are indicated only support values > 50% are shown. NlSPARC is marked with filled triangle. All protein sequences (accession numbers, length and pI) obtained from GenBank was listed in Table...

Additional file 3 of SPARC plays an important role in the oviposition and nymphal development in Nilaparvata lugens Stål

Weixia Wang, Tingheng Zhu, Pinjun Wan, Qi Wei, Jiachun He, Fengxiang Lai & Qiang Fu
Additional file 3: Figure. S2. Relative expression of NlSPARC,NlVg,NlVgR, and NlFoxO in newly emerged adults developed from injected 5th instar nymphs. mRNA levels of NlSPARC, NlVg, NlVgR, and NlFoxO from 5 newly emerged females were analyzed by RT-qPCRwith the 2‒ΔΔCT method from three biological replicates (Mean ± SE). ** above the bars indicate significant differences at P < 0.01 among different treatments by the Tukey’s multiple range tests.

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