58 Works

Serum 25(OH)D level on hospital admission is correlated with COVID-19 mortality

Geert Martens
Objective: Vitamin D deficiency was previously correlated with incidence and severity of COVID-19. We investigated the correlation between serum 25(OH)D level on admission and radiological stage and outcome of COVID-19 pneumonia. Methods: Retrospective observational trial on 186 SARS-CoV-2-infected individuals hospitalized from March 1, 2020 to April 7, 2020 with combined chest CT and 25(OH)D measurement on admission. Multivariate analysis was performed to study if vitamin D deficiency (25(OH)D < 20 ng/mL) predicts survival independently of...

Data from: Prey colonization in freshwater landscapes can be stimulated or inhibited by the proximity of remote predators

Beth Turner, Hendrik Trekels, Mathil Vandromme & Bram Vanschoenwinkel
1. Recent findings suggest that the colonization of habitat patches may be affected by the quality of surrounding patches. For instance, patches that lack predators may be avoided when located near others with predators, a pattern known as risk contagion. Alternatively, predator avoidance might also redirect dispersal towards nearby predator-free patches resulting in so-called habitat compression. However, it is largely unknown how predators continue to influence these habitat selection behaviors at increasing distances from outside...

ISIMIP3a lakes input data

Inne Vanderkelen & Jacob Schewe
The Inter-Sectoral Impact Model Intercomparison Project (ISIMIP) provides a framework for the collation of a consistent set of climate impact data across sectors and scales. It also provides a unique opportunity for considering interactions between climate change impacts across sectors through consistent scenarios.
The ISIMIP3a part of the third simulation round is dedicated to i) impact model evaluation and improvement and ii) detection and attribution of observed impacts according to the framework of IPCC AR5 Working...

Experimental data: Inferring strategies from observations in long iterated prisoner’s dilemma experiments

Eladio Montero
While many theoretical studies have revealed the strategies that could lead to and maintain cooperation in the Iterated Prisoner's Dilemma, less is known about what human participants actually do in this game and how strategies change when being confronted with anonymous partners in each round. Previous attempts used short experiments, made different assumptions of possible strategies, and led to very different conclusions. We present here two long treatments that differ in the partner matching strategy...

ISIMIP3 geographical lakes input data

Inne Vanderkelen, Daniel Mercado-Bettin & Jacob Schewe
The Inter-Sectoral Impact Model Intercomparison Project (ISIMIP) provides a framework for the collation of a consistent set of climate impact data across sectors and scales. It also provides a unique opportunity for considering interactions between climate change impacts across sectors through consistent scenarios.
The ISIMIP3a part of the third simulation round is dedicated to i) impact model evaluation and improvement and ii) detection and attribution of observed impacts according to the framework of IPCC AR5 Working...

Per- and polyfluoroalkyl substances (PFAS) and neurobehavioral function and cognition in adolescents (2010–2011) and elderly people (2014): results from the Flanders Environment and Health Studies (FLEHS)

Nicolas van Larebeke, Gudrun Koppen, Sam Decraemer, Ann Colles, Liesbeth Bruckers, Elly Den Hond, Eva Govarts, Bert Morrens, Thomas Schettgen, Sylvie Remy, Dries Coertjens, Tim Nawrot, Vera Nelen, Willy Baeyens & Greet Schoeters
Abstract Background PFAS are persistent, bioaccumulative compounds repelling water, oil and stains which are widely used. There is mounting evidence linking exposure to a range of adverse health outcomes including renal, hepatic, immunotoxic, reproductive, endocrine disrupting and carcinogenic effects. PFAS possibly also induce neurobehavioral and developmental effects. Within Flanders Environment and Health Studies (FLEHS) internal exposure to PFAS and relevant health effects are assessed since 2008. Results Adolescents 14–15 y (2010–2011) living in an industrially...

Incorporating ‘reason for use’ into the prescribing process of medication: a survey on the opinion of patients in Flanders, Belgium

Marijke Peeters, Elias Iturrospe, Dominique Jans, Alexander L. N. van Nuijs & Hans De Loof
Abstract Background A longstanding debate exists about including a ‘reason for use’ on prescriptions for medication. Little is known, however, about patients’ opinions on this subject. Methods An internet-based questionnaire, consisting mainly of Likert scale questions, was distributed online to the general public in Belgium. Results from 1034 responses were analyzed using descriptive statistics. Results Opinions from patients toward including a ‘reason for use’ on medication prescriptions were generally positive. A clear majority of 62%...

Data from: Parallel tagged amplicon sequencing of transcriptome-based genetic markers for Triturus newts with the Ion Torrent next-generation sequencing platform

Ben Wielstra, Elza Duijm, Patricia Lagler, Youri Lammers, Willem R. M. Meilink, Janine M. Ziermann & Jan W. Arntzen
Next-generation sequencing is a fast and cost-effective way to obtain sequence data for non-model organisms for many markers and for many individuals. We describe a protocol through which we obtain orthologous markers for the crested newts (Amphibia: Salamandridae: Triturus), suitable for analysis of interspecific hybridization. We use transcriptome data of a single Triturus species and design 96 primer pairs that amplify c. 180 bp fragments positioned in 3-prime untranslated regions. Next these markers are tested...

Data from: Functional advantages of conserved intrinsic disorder in RNA-binding proteins

Mihaly Varadi, Fruzsina Zsolyomi, Mainak Guharoy & Peter Tompa
Proteins form large macromolecular assemblies with RNA that govern essential molecular processes. RNA-binding proteins have often been associated with conformational flexibility, yet the extent and functional implications of their intrinsic disorder have never been fully assessed. Here, through large-scale analysis of comprehensive protein sequence and structure datasets we demonstrate the prevalence of intrinsic structural disorder in RNA-binding proteins and domains. We addressed their functionality through a quantitative description of the evolutionary conservation of disordered segments...

Data from: Socio-demographic, social-cognitive, health-related and physical environmental variables associated with context-specific sitting time in Belgian adolescents: a one-year follow-up study

Cedric Busschaert, Nicola D. Ridgers, Ilse De Bourdeaudhuij, Greet Cardon, Jelle Van Cauwenberg & Katrien De Cocker
Introduction: More knowledge is warranted about multilevel ecological variables associated with context-specific sitting time among adolescents. The present study explored cross-sectional and longitudinal associations of ecological domains of sedentary behaviour, including socio-demographic, social-cognitive, health-related and physical-environmental variables with sitting during TV viewing, computer use, electronic gaming and motorized transport among adolescents. Methods: For this longitudinal study, a sample of Belgian adolescents completed questionnaires at school on context-specific sitting time and associated ecological variables. At baseline,...

Data from: Mutation accumulation is still potentially problematic, despite declining paternal age: a comment on Arslan et al. (2017).

Michael A. Woodley Of Menie, Matthew A. Sarraf & Heitor B. F. Fernandes
Icelandic mutation accumulation modelIcelandic mutation accumulation model (Ibs 0.5-0.99 and Ibs 0.35) - secondary analysis of data from Kong et al. (2012) Rate of de novo mutations and the importance of father’s age to disease risk. Nature 488, 471–475. (doi:10.1038/nature11396), Fig. 4, p.474.

Data from: Nutrient availability controls the impact of mammalian herbivores on soil carbon and nitrogen pools in grasslands

Judith Sitters, E.R. Jasper Wubs, Elisabeth S. Bakker, Thomas W. Crowther, Peter B. Adler, Sumanta Bagchi, Jonathan D. Bakker, Lori Biederman, Elizabeth T. Borer, Elsa E. Cleland, Nico Eisenhauer, Jennifer Firn, Laureano Gherardi, Nicole Hagenah, Yann Hautier, Sarah E. Hobbie, Johannes M.H. Knops, Andrew S. MacDougall, Rebecca L. McCulley, Joslin L. Moore, Brent Mortensen, Pablo L. Peri, Suzanne M. Prober, Charlotte Riggs, Anita C. Risch … &
Grasslands have been subject to considerable alteration due to human activities globally, including widespread changes in populations and composition of large mammalian herbivores and elevated supply of nutrients. Grassland soils remain important reservoirs of carbon (C) and nitrogen (N). Herbivores may affect both C and N pools and these changes likely interact with increases in soil nutrient availability. Given the scale of grassland soil fluxes, such changes can have striking consequences for atmospheric C concentrations...

Microsatellite data of 14 Avicennia marina populations from Mozambique Channel area

Ludwig Triest
Mangrove forests are dynamic ecosystems found along sheltered low-lying coastal plains in warm-temperate, tropical and subtropical regions, predominantly on tidal flats, deltas, estuaries, bays, but also on oceanic atolls. These landforms present varied hydrodynamic and geomorphological settings for mangroves to establish and could influence the extent of propagule transport and subsequent regeneration. In this study, we examined whether these landform characteristics influence the genetic diversity and structure of Avicennia marina, one of the most abundant...

Proton-transfer-reaction time-of-flight mass spectrometry (PTR-TOF-MS) as a tool for studying animal volatile organic compound (VOC) emissions

Miguel Portillo-Estrada, Charlotte Van Moorleghem, Sunita Janssenswillen, Richard Joseph Cooper, Claudia Birkemeyer, Kim Roelants & Raoul Van Damme
1. Chemical sensing in vertebrates is crucial in their lives, and efforts are undertaken towards deciphering their chemical language. Volatile organic compounds (VOCs) is a group of chemicals believed to play an essential role in a wide variety of animal interactions. Therefore, understanding what animals sense themselves and untangling the ecological role of their volatile cues can be accomplished by analysing VOC emissions. A Proton-Transfer Reaction Time-of-Flight Mass Spectrometer (PTR-TOF-MS) is an instrument that measures...

Timing uncertainty in collective risk dilemmas encourages group reciprocation and polarization

Elias Fernandez Domingos, Jelena Grujić, Francisco C. Santos, Juan C. Burguillo Rial, Georg Kirchsteiger, Francisco C. Santos & Tom Lenaerts
Social dilemmas are often shaped by actions involving uncertain returns only achievable in the future, such as climate action or voluntary vaccination. In this context, uncertainty may produce non-trivial effects. Here, we assess experimentally — through a collective risk dilemma — the effect of timing uncertainty, i.e. how uncertainty about when a target needs to be reached affects the participants’ behaviours. We show that timing uncertainty prompts not only early generosity but also polarised outcomes,...

Belgium (Flanders)

Jonathan  Hendrickx , Pauljan Truyens, Karen  Donders  & Ike  Picone

ISIMIP3b lakes fraction input data

Inne Vanderkelen, Daniel Mercado-Bettin & Jacob Schewe
The data are derived from the HydroLAKES v1.0 (Messager et al., 2016) and GRanD v1.3 (Lehner et al., 2011) databases and rasterized using the polygon_to_cellareafraction tool (Vanderkelen 2021, available on GitHub), and mapped to 0.5 degrees resolution. Time steps represent increasing reservoirs in their construction year, as given by GRanD.

Future changes in mangrove coastal water properties

Tom Van Der Stocken
This dataset contains data on future changes in sea-surface water properties along the global distribution of mangrove forests. This includes the coordinates of mangrove occurence and associated information on present (2000-2014) and future (2090-2100) sea-surface temperature (SST), sea-surface salinity (SSS), and sea-surface density (SSD, derived from SST and SSS, using the UNESCO EOS-80 equation of state polynomial for seawater - 'sw_dens.m' in MATLAB). SST and SSS fields from which the data were extracted, are from...

Additional file 1 of Per- and polyfluoroalkyl substances (PFAS) and neurobehavioral function and cognition in adolescents (2010–2011) and elderly people (2014): results from the Flanders Environment and Health Studies (FLEHS)

Nicolas van Larebeke, Gudrun Koppen, Sam Decraemer, Ann Colles, Liesbeth Bruckers, Elly Den Hond, Eva Govarts, Bert Morrens, Thomas Schettgen, Sylvie Remy, Dries Coertjens, Tim Nawrot, Vera Nelen, Willy Baeyens & Greet Schoeters
Additional file 1 : Table S1. FLEHS-2 campaign on adolescents. List of confounders and potential covariates included in stepwise multiple or logistic regressions. Table S2. FLESH-3 campaign on adults. List of confounders and potential covariates included in stepwise multiple or logistic regressions. Table S3. Association of blood concentrations of perfluoro compounds with ln-transformed cognitive and neuropsychological parameters. Table S4. Association of blood concentrations of perfluoro compounds with non-transformed cognitive and neuropsychological parameters.

Data from: Functional diversity and structural disorder in the human ubiquitination pathway

Pallab Bhowmick, Rita Pancsa, Mainak Guharoy & Peter Tompa
The ubiquitin-proteasome system plays a central role in cellular regulation and protein quality control (PQC). The system is built as a pyramid of increasing complexity, with two E1 (ubiquitin activating), few dozen E2 (ubiquitin conjugating) and several hundred E3 (ubiquitin ligase) enzymes. By collecting and analyzing E3 sequences from the KEGG BRITE database and literature, we assembled a coherent dataset of 563 human E3s and analyzed their various physical features. We found an increase in...

Data from: A refugee camp in the center of Europe: clinical characteristics of asylum seekers arriving in brussels

Gerlant Van Berlaer, Francisca Bohle Carbonell, Sofie Manantsoa, Xavier De Béthune, Ronald Buyl, Michel Debacker & Ives Hubloue
Background In the summer of 2015, the exodus of Syrian war refugees and saturation of refugee camps in neighboring countries led to the influx of asylum-seekers in European countries, including Belgium. This study aims to describe the demographic and clinical characteristics of asylum-seekers that arrived in a huddled refugee camp, in the center of a well-developed country with all medical facilities. Methods Using a descriptive cross-sectional study design, physicians of Médecins du Monde prospectively registered...

Data from: Integrative taxonomy of root-knot nematodes reveals multiple independent origins of mitotic parthenogenesis

Toon Janssen, Gerrit Karssen, Olivera Topalović, Danny Coyne & Wim Bert
During sampling of several Coffea arabica plantations in Tanzania severe root galling, caused by a root-knot nematode was observed. From pure cultures, morphology and morphometrics of juveniles and females matched perfectly with Meloidogyne africana, whereas morphology of the males matched identically with those of Meloidogyne decalineata. Based on their Cox1 sequence, however, the recovered juveniles, females and males were confirmed to belong to the same species, creating a taxonomic conundrum. Adding further to this puzzle,...

Data from: What caused over a century of decline in general intelligence? Testing predictions from the genetic selection and neurotoxin hypotheses

Michael A. Woodley Of Menie, Matthew A. Sarraf, Mateo Peñaherrera-Aguirre, Heitor B.F. Fernandes & David Becker
Several converging lines of evidence indicate that general intelligence (g) has declined in Western populations. The causes of these declines are debated. Here, two hypotheses are tested: (1) selection acting against genetic variants that promote g causes the decline and (2) the presence of neurotoxic pollution in the environment causes the decline. A linear mixed model was devised to test (1) and (2), in which the secular decline in a “heritable g” (g.h) chronometric factor...

Hidden hybridization and habitat differentiation ina Mediterranean macrophyte, the euryhaline genus Ruppia

Lise Beirinckx, Bram Vanschoenwinkel & Ludwig Triest
In many aquatic plant taxa, classification and identification based on morphology has always been difficult. Molecular markers revealed that the complexity in several of these aquatic taxa could be addressed to recurrent hybridization events and cryptic species diversity. The submerged macrophyte genus Ruppia is one of these aquatic genera with a complex taxonomy due to the absence of clear distinguishable traits and several hybridization events. Two species co-exist throughout Europe, R. maritima and R. spiralis...

Data from: Do people imitate when making decisions? - evidence from a spatial prisoners dilemma experiment

Jelena Grujic & Tom Lenaerts
How do people decide which action to take? This question is best answered using Game Theory, which has proposed a series of decision mechanisms that people potentially use. In network simulations, wherein games are repeated and payoff differences can be observed, those mechanisms rely often on imitation of successful behavior. Surprisingly, little to no evidence has been provided about whether, how and what people actually use to alter their actions in that context. By comparing...

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