4 Works

Data from: Exogenous α-synuclein hinders synaptic communication in cultured cortical primary rat neurons

Gerco C. Hassink, Christian C. Raiss, M.J. Segers-Nolten, Richard J.A. Van Wezel, Vinod Subramaniam, Joost Le Feber, Mireille M.A.E. Claessens, M. M. A. E. Claessens, R. J. A. Van Wezel & I. M. J. Segers-Nolten
Amyloid aggregates of the protein α-synuclein (αS) called Lewy Bodies (LB) and Lewy Neurites (LN) are the pathological hallmark of Parkinson's disease (PD) and other synucleinopathies. We have previously shown that high extracellular αS concentrations can be toxic to cells and that neurons take up αS. Here we aimed to get more insight into the toxicity mechanism associated with high extracellular αS concentrations (50-100 μM). High extracellular αS concentrations resulted in a reduction of the...

Data from: 18F-fluorodeoxyglucose positron-emission tomography (FDG-PET)-Radiomics of metastatic lymph nodes and primary tumor in non-small cell lung cancer (NSCLC) – A prospective externally validated study

Sara Carvalho, Ralph T. H. Leijienaar, Esther G. C. Troost, Janna E. Van Timmeren, Cary Oberije, Wouter Van Elmpt, Lioe-Fee De Geus-Oei, Johan Bussink, Philippe Lambin & Ralph T. H. Leijenaar
Background: Lymph node stage prior to treatment is strongly related to disease progression and poor prognosis in non-small cell lung cancer (NSCLC). However, few studies have investigated metabolic imaging features derived from pre-radiotherapy 18F-fluorodeoxyglucose (FDG) positron-emission tomography (PET) of metastatic hilar/mediastinal lymph nodes (LNs). We hypothesized that these would provide complementary prognostic information to FDG-PET descriptors to only the primary tumor (tumor). Methods: Two independent cohorts of 262 and 50 node-positive NSCLC patients were used...

Data from: Past distribution of epiphyllous liverworts in China: the usability of historical data

Yanbin Jiang, Tiejun Wang, Yupeng Wu, Ronggui Hu, Ke Huang & Xiaoming Shao
Epiphyllous liverworts form a special group of bryophytes that primarily grow on the leaves of understory vascular plants in tropical and subtropical evergreen broadleaf forests. Being sensitive to moisture and temperature changes, epiphyllous liverworts are often consider to be good indicators of climate change and forest degradation. However, they are a poorly collected and taxonomically complicated group, with an only partly identified distribution pattern. In this study, we built four models based on 24 environmental...

Data from: Large birds travel farther in homogeneous environments

Marlee A. Tucker, Olga Alexandrou, , Keith L. Bildstein, Katrin Böhning-Gaese, Chloe Bracis, John N. Brzorad, Evan R. Buechley, David Cabot, Justin M. Calabrese, Carlos Carrapato, André Chiaradia, Lisa C. Davenport, Sarah C. Davidson, Mark Desholm, Christopher R. DeSorbo, Robert Domenech, Peter Enggist, William F. Fagan, Nina Farwig, Wolfgang Fiedler, Christen H. Fleming, Alastair Franke, John M. Fryxell, Clara García-Ripollés … & João Paulo Silva
Aim: Animal movement is an important determinant of individual survival, population dynamics, and ecosystem structure and function. Yet it is still unclear how local movements are related to resource availability and the spatial arrangement of resources. Using resident bird species and migratory bird species outside of the migratory period, we examined how the distribution of resources affect the movement patterns of both large terrestrial birds (e.g., raptors, bustards, hornbills) and waterbirds (e.g., cranes, storks, ducks,...

Registration Year

  • 2018

Resource Types

  • Dataset


  • University of Twente
  • Max Planck Institute for Ornithology
  • Friends University
  • Biodiversity Research Institute
  • Columbia University
  • Université Paul-Valéry Montpellier
  • The Ohio State University
  • University of Georgia
  • Royal Society for the Protection of Birds
  • University of Alberta