Data from: Medically important differences in snake venom composition are dictated by distinct postgenomic mechanisms

Nicholas R. Casewell, Simon C. Wagstaff, Wolfgang W├╝ster, Darren A. N. Cook, Fiona M. S. Bolton, Sarah I. King, Davinia Pla, Libia Sanz, Juan J. Calvete & Robert A. Harrison
Variation in venom composition is a ubiquitous phenomenon in snakes and occurs both interspecifically and intraspecifically. Venom variation can have severe outcomes for snakebite victims by rendering the specific antibodies found in antivenoms ineffective against heterologous toxins found in different venoms. The rapid evolutionary expansion of different toxin-encoding gene families in different snake lineages is widely perceived as the main cause of venom variation. However, this view is simplistic and disregards the understudied influence that...

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