109 Works

St-ATT: The Starting Anti-Tuberculosis Treatment Cohort in the Philippines

Sharon Cox & Benjamin Faguer

Antenatal code list for: \"The effects of antenatal care, ethnicity and social deprivation on the risk of stillbirth in the UK: A cohort study using routinely collected data\"

Amanda Clery, Caroline Minnasian, Liam Smeeth & Rohini Mathur
A list of Read codes and entity types used to identify events in the Clinical Practice Research Datalink that identify the antenatal appointments women in the Pregnancy Register had. These were used to quantify the frequency and timing of antenatal care, the exposure variable for the study.

Data for: Rapid Assessment of Hearing Loss survey in Malawi

Tess Bright

Clinical risk groups for Pneumococcal Polysaccharide Vaccine

Helen McDonald, Dai Evans, Simon Clay, Michael Edelstein & Sara Thomas
Read codes associated with a paper on clinical risk groups for a Pneumococcal Polysaccharide Vaccine.

Data from: A randomized feasibility trial comparing four antimalarial drug regimens to induce Plasmodium falciparum gametocytemia in the controlled human malaria infection model

Isaie J. Reuling, Lisanne A Van De Schans, Luc E Coffeng, Kjerstin Lanke, Lisette Meerstein-Kessel, Wouter Graumans, Geert-Jan Van Gemert, Karina Teelen, Rianne Siebelink-Stoter, Marga Van De Vegte-Bolmer, Quirijn De Mast, André J Van Der Ven, Karen Ivinson, Cornelus C Hermsen, Sake De Vlas, John Bradley, Katharine A Collins, Christian F Ockenhouse, James McCarthy, Robert W. Sauerwein & Teun Bousema
Background: Malaria elimination strategies require a thorough understanding of parasite transmission from human to mosquito. A clinical model to induce gametocytes to understand their dynamics and evaluate transmission-blocking interventions (TBI) is currently unavailable. Here, we explore the use of the well-established Controlled Human Malaria Infection model (CHMI) to induce gametocyte carriage with different antimalarial drug regimens. Methods: In a single centre, open-label randomised trial, healthy malaria-naive participants (aged 18–35 years) were infected with Plasmodium falciparum...

Data from: Clarifying life lost due to cold and heat: a new approach using annual time series.

Nirandeep Rehill, Ben Armstrong & Paul Wilkinson
Objective: To clarify whether deaths associated with hot and cold days are among the frail who would have died anyway in the next few weeks or months. Design: Time series regression analysis of annual deaths in relation to annual summaries of cold and heat. Setting: London, UK. Participants: 3 530 280 deaths from all natural causes among London residents between October 1949 and September 2006. Main outcome measures: Change in annual risk of death (all...

Data from: Understanding willingness to use oral pre-exposure prophylaxis for HIV prevention among men who have sex with men in China

Xia Wang, Adam Bourne, Pulin Liu, Jiangli Sun, Thomas Cai, Gitau Mburu, Matteo Cassolato, Bangyuan Wang & Wang Zhou
Background: Oral pre-exposure prophylaxis (PrEP) is recommended as an additional prevention choice for men who have sex with men (MSM) at substantial risk of HIV. The aim of this study was to evaluate the extent, and reasons, for MSM’s willingness to use oral PrEP in Wuhan and Shanghai, China. Methods: Between May and December 2015, a cross-sectional survey was conducted among 487 MSM recruited through snowball sampling in physical locations frequented by MSM and through...

Data from: Safety and immunogenicity of H1/IC31®, an adjuvanted TB subunit vaccine, in HIV-infected adults with CD4+ Lymphocyte counts greater than 350 cells/mm3: a phase II, multi-centre, double-blind, randomized, placebo-controlled trial

Klaus Reither, Lynn Katsoulis, Trevor Beattie, Nicolene Gardiner, Nicole Lenz, Khadija Said, Elirehema Mfinanga, Christian Pohl, Katherine L. Fielding, Hannah Jeffery, Benjamin M. Kagina, Elisabeth J. Hughes, Thomas J. Scriba, Willem A. Hanekom, Søren T. Hoff, Peter Bang, Ingrid Kromann, Claudia Daubenberger, Peter Andersen & Gavin J. Churchyard
Background: Novel tuberculosis vaccines should be safe, immunogenic, and effective in various population groups, including HIV-infected individuals. In this phase II multi-centre, double-blind, placebo-controlled trial, the safety and immunogenicity of the novel H1/IC31 vaccine, a fusion protein of Ag85B-ESAT-6 (H1) formulated with the adjuvant IC31, was evaluated in HIV-infected adults. Methods: HIV-infected adults with CD4+ T cell counts >350/mm3 and without evidence of active tuberculosis were enrolled and followed until day 182. H1/IC31 vaccine or...

Clinical code lists for: \"The effects of antenatal care, ethnicity and social deprivation on the risk of stillbirth in the UK: A cohort study using routinely collected data\"

Amanda Clery, Caroline Minassian, Liam Smeeth & Rohini Mathur
Clinical code lists for: "The effects of antenatal care, ethnicity and social deprivation on the risk of stillbirth in the UK: A cohort study using routinely collected data"

Codelists for: \"Factors associated with excess mortality in the first wave of COVID-19 pandemic in the UK: a cohort analysis using the Clinical Practice Research Databank\"

Jennifer Davidson, Charlotte Warren-Gash, Helen Mcdonald, Ami Banerjee, Alicia Gayle, Helen Strongman, Dai Evans, Simon Clay, Harriet Forbes, Kathryn E. Mansfield, Helena Carreira, Krishnan Bhaskaran, Ketaki Bhate, Liam Smeeth, Daniel Dedman, Rohini Mathur, Sharon Cadogan & LSHTM Electronic Health Records team

Behavioural change towards reduced intensity physical activity is disproportionately prevalent among adults with serious health issues or self-perception of high risk during the UK COVID-19 lockdown.

Chrissy Roberts, Nina Rogers, Naomi Waterlow, Hannah Brindle, Luisa Enria & Shelley Lees
Quantitative data on physical activity and health behaviours during the UK COVID-19 lockdown. The anonymous web-based survey was performed between 6th April and 22 April 2020, approximately mapping to weeks 3-5 of the lockdown in the UK. The main survey included 49 questions which covered a broad range of topics including (1) Demographics, (2) Health and Health Behaviours, (3) Adherence to COVID-19 Control measures, (4) Information sources used to learn about COVID-19, (5) Trust in...

R code for: \"Confirmatory testing with a second lateral flow test may mitigate false positives at low levels of SARS-CoV-2 prevalence in English schools\"

Billy J Quilty, Joel Hellewell, Sam Clifford &

Effectiveness of a peer-led adolescent mental health intervention on HIV virological suppression and mental health in Zimbabwe: Baseline and Endline questionnaires

Vicky Simms & Silindweyinkosi Chinoda
Adolescents living with HIV have poor virological suppression and high levels of common mental disorders. In Zimbabwe the Zvandiri adolescent peer support programme is effective at improving ART adherence and virological suppression. We assessed the effect of training peer supporters in problem-solving therapy (PST) using a cluster-randomised controlled trial. Sixty clinics stratified by district were randomised 1:1 to either normal Zvandiri peer support or a peer supporter trained in PST by Friendship Bench. We enrolled...

Data from: The impact of long-term azithromycin on antibiotic resistance in HIV-associated chronic lung disease

Regina Esinam Abotsi, Mark P. Nicol, Grace McHugh, Victoria Simms, Andrea M. Rehman, Charmaine Barthus, Lucky G. Ngwira, Brenda Kwambana-Adams, Robert S Heyderman, Jon Ø Odland, Rashida A Ferrand & Felix S. Dube
Background: Selection for resistance to azithromycin (AZM) and other antibiotics such as tetracyclines and lincosamides remains a concern with long-term AZM use for treatment of chronic lung diseases (CLD). We investigated the impact of 48 weeks of AZM on the carriage and antibiotic resistance of common respiratory bacteria among children with HIV-associated CLD. Methods: Nasopharyngeal (NP) swabs and sputa were collected at baseline, 48 and 72 weeks from participants with HIV-associated CLD randomised to receive...

Clinical codelist - CPRD Gold - dementia diagnoses and subtypes

Charlotte Warren-Gash
Read codes for dementia subtypes.

Combined HIV Adolescent Prevention Study (CHAPS)

Emily Webb

Dataset for: The effect of cumulative early life adversities, and their differential mediation through hair cortisol levels, on childhood growth and cognition: Three-year follow-up of a birth cohort in rural India

Mukherjee Mukherjee, Sunil Bhopal, Supriya Bhavnani, Kamal Kant Sharma, Reetabrata Roy, Gauri Divan, Siddhartha Mandal, Betty Kirkwood & Vikram Patel
The SPRING-ELS sub-study of the SPRING cluster randomised controlled trial included 1304 children that had adversity exposure assessment conducted at 12 months of age. Hair cortisol concentration was assessed in 845 of them at this time. As part of the REACH follow-up study, 1124 children (of the 1304 with adversity assessments) were followed-up at three years of age to assess height, weight and cognition using the Developmental Assessment on an E-Platform (DEEP) tool. 607 children...

MAISHA Cluster Randomised Trial - Couples Survey Data

Tanya Abramsky & Sheila Harvey
The MAISHA study (component A) is a mixed-methods evaluation, including a cluster randomised trial (CRT), of a small group based social empowerment intervention to prevent intimate partner violence (IPV) against women in Mwanza city, Tanzania. The trial was conducted among women already participating in a group-based microfinance scheme, with the microfinance group being the unit of randomisation and (in the intervention arm) the unit of intervention delivery. The CRT involved two surveys of trial participants...

Data repository for AZ-SMC - a trial of seasonal malaria chemoprevention combined with azithromycin in African children

Daniel Chandramohan, Alassane Dicko, Issaka Zongo, Issaka Sagara, Matthew Cairns, Irene Kuepfer, Modibo Diarra, Barry Amadou, Amadou Tapily, Frederic Nikiema, Serge Yerbanga, Samba Coumare, Ismaila Thera, Abdourhamane Traore, Paul Milligan, Halidou Tinto, Ogobara Doumbo, Jean-Bosco Ouedraogo & Brian Greenwood
Data collected during the AZ-SMC trial (clinicaltrials.gov NCT02211729) in Houndé District, Burkina Faso and Bougouni District, Mali between 2014 and 2016.

Code lists for: \"Estimating the incidence of acute complications of herpes zoster among immunocompetent adults in England\"

Harriet Forbes

Codelists for \"Herpes zoster and dementia risk: a population-based matched cohort study\".

Charlotte Warren-Gash, Jennifer Davidson, Helen Mcdonald, Sharon Cadogan, Harriet Forbes, Helen Strongman, Sinead Langan, Kathryn E. Mansfield, Liam Smeeth, Rutendo Muzambi, Suhail Shiekh &

Clinical codelist - CPRD Gold - depression

Charlotte Warren-Gash
Read codes for depression.

Codelists for: \"Adverse outcomes after partner bereavement in people with reduced kidney function: parallel cohort studies in England and Denmark\"

Patrick Bidulka & Vestergaard Søren Viborg

Registration Year

  • 2022
  • 2021
  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013

Resource Types

  • Dataset
  • Collection
  • Text
  • Data Paper
  • Interactive Resource
  • Journal Article
  • Report
  • Software


  • London School of Hygiene & Tropical Medicine
  • Radboud University Nijmegen
  • Medical Research Council
  • Centre National de Recherche et de Formation sur le Paludisme
  • University College London
  • Imperial College London
  • Radboud University Nijmegen Medical Centre
  • Biomedical Research and Training Institute
  • Erasmus University Medical Center
  • Aarhus University