719 Works

Analysis of sputum microbial metagenome in COPD based on exacerbation frequency and lung function: a case control study

Wei Li, Bingbing Wang, Min Tan, Xiaolian Song, Shuanshuan Xie & Changhui Wang
Abstract Background The role of the sputum microbiome in chronic obstructive pulmonary disease (COPD) progression remains elusive. As the advent of the new culture-independent microbial sequencing technique makes it possible to disclose the complex microbiome community of the respiratory tract. The aim of this study was to use metagenomic next-generation sequencing (mNGS) to confirm whether there are differences in sputum microbiome of COPD between different exacerbation frequencies and lung function. Methods Thirty-nine COPD patients were...

Additional file 1 of Endolysins of bacteriophage vB_Sal-S-S10 can naturally lyse Salmonella enteritidis

Xinrui Wang, Lili Han, Jiaqing Rong, Huiying Ren, Wenhua Liu & Can Zhang
Additional file 1.

Additional file 2 of Impacts of metabolic disorders on short- and long-term mortality after coronary artery surgery in the elderly

Yuhong Fan, Jingjing Liu, Lei Jin, Zhonghe Liu, Lixiang Han, Yue Wang, Yangyang Zhang, Peiming Shen & Zhi Li
Additional file 2. Fig. S1: Standardized differences for each variable before and after PSM. The absolute standardized differences < 0.2 indicate balanced matching. Y axis represents the baseline of variables. X axis represents the standardized mean difference value. PSM, propensity score matching; EuroSCORE II, European system for cardiac operative risk evaluation II; IABP, intra-aortic balloon pump; PCI, percutaneous coronary intervention; COPD, chronic obstructive pulmonary disease; Scr, serum creatinine; LVEF, left ventricular ejection fraction; NYHA, New...

Pre-concentration of quartz from sea sand through superconducting high gradient magnetic separation technology

Yongkui Li, Suqin Li, Xiaodong Pan, Xin Zhao & Penghui Guo
In this study, a superconducting high gradient magnetic separation (S-HGMS) technology was used to separate and extract quartz from sea sand. Under optimal conditions (i.e., a magnetic flow ratio of 0.085 T·s/m, slurry flow velocity of 400 ml/min, and pulp concentration of 40 g/L), the SiO2 grade increased from 79.45% of the raw material to 91.35% of quartz concentrate, and the removal rate of Al and Fe reached 91.97% and 82.10%, respectively. Weakly magnetic particles...

sj-pdf-2-imr-10.1177_03000605221139667 - Supplemental material for Osteoperiosteal decortication and bone grafting combined with wave plating for femoral shaft aseptic atrophic nonunion after intramedullary nailing

Yao Lu, Liang Sun, Qian Wang, Cheng Ren, Yibo Xu, Haobo Ye, Ming Li, Hanzhong Xue, Qiang Huang, Zhong Li, Kun Zhang & Teng Ma
Supplemental material, sj-pdf-2-imr-10.1177_03000605221139667 for Osteoperiosteal decortication and bone grafting combined with wave plating for femoral shaft aseptic atrophic nonunion after intramedullary nailing by Yao Lu, Liang Sun, Qian Wang, Cheng Ren, Yibo Xu, Haobo Ye, Ming Li, Hanzhong Xue, Qiang Huang, Zhong Li, Kun Zhang and Teng Ma in Journal of International Medical Research

Supplemental Material - Machine Learning Predict Survivals of Spinal and Pelvic Ewing’s Sarcoma with the SEER Database

Guoxin Fan, Sheng Yang, Jiaqi Qin, Longfei Huang, Yufeng Li, Huaqing Liu & Xiang Liao
Supplemental Material for Machine Learning Predict Survivals of Spinal and Pelvic Ewing’s Sarcoma with the SEER Database by Guoxin Fan, Sheng Yang, Jiaqi Qin, Longfei Huang, Yufeng Li, Huaqing Liu, Xiang Liao in Global Spine Journal

Additional file 2 of A comprehensive update on CIDO: the community-based coronavirus infectious disease ontology

Yongqun He, Hong Yu, Anthony Huffman, Asiyah Yu Lin, Darren A. Natale, John Beverley, Ling Zheng, Yehoshua Perl, Zhigang Wang, Yingtong Liu, Edison Ong, Yang Wang, Philip Huang, Long Tran, Jinyang Du, Zalan Shah, Easheta Shah, Roshan Desai, Hsin-hui Huang, Yujia Tian, Eric Merrell, William D. Duncan, Sivaram Arabandi, Lynn M. Schriml, Jie Zheng … & Barry Smith
Additional file 2: Supplemental Table 1. Resources used for our coronavirus disease-related data collection.

Additional file 2 of A comprehensive update on CIDO: the community-based coronavirus infectious disease ontology

Yongqun He, Hong Yu, Anthony Huffman, Asiyah Yu Lin, Darren A. Natale, John Beverley, Ling Zheng, Yehoshua Perl, Zhigang Wang, Yingtong Liu, Edison Ong, Yang Wang, Philip Huang, Long Tran, Jinyang Du, Zalan Shah, Easheta Shah, Roshan Desai, Hsin-hui Huang, Yujia Tian, Eric Merrell, William D. Duncan, Sivaram Arabandi, Lynn M. Schriml, Jie Zheng … & Barry Smith
Additional file 2: Supplemental Table 1. Resources used for our coronavirus disease-related data collection.

A comprehensive update on CIDO: the community-based coronavirus infectious disease ontology

Yongqun He, Hong Yu, Anthony Huffman, Asiyah Yu Lin, Darren A. Natale, John Beverley, Ling Zheng, Yehoshua Perl, Zhigang Wang, Yingtong Liu, Edison Ong, Yang Wang, Philip Huang, Long Tran, Jinyang Du, Zalan Shah, Easheta Shah, Roshan Desai, Hsin-hui Huang, Yujia Tian, Eric Merrell, William D. Duncan, Sivaram Arabandi, Lynn M. Schriml, Jie Zheng … & Barry Smith
Abstract Background The current COVID-19 pandemic and the previous SARS/MERS outbreaks of 2003 and 2012 have resulted in a series of major global public health crises. We argue that in the interest of developing effective and safe vaccines and drugs and to better understand coronaviruses and associated disease mechenisms it is necessary to integrate the large and exponentially growing body of heterogeneous coronavirus data. Ontologies play an important role in standard-based knowledge and data representation,...

Conductive, self-healing, and antibacterial Ag/MXene-PVA hydrogel as wearable skin-like sensors

Lumin Li, Xiaofeng Ji & Kai Chen
The rapid development of flexible electronic technology has led to the in-depth study of flexible wearable sensors to achieve accurate sensing under different external stimuli. However, it is still a huge challenge to develop hydrogel-based wearable skin-like sensors with super ductility, high sensitivity, and self-healing properties. Herein, the Ti3C2 type of MXene was synthesized, and the Ag/MXene nanocomplexes were incorporated into polyvinyl alcohol-borax matrix to construct a novel composite hydrogel as the multifunctional nanofillers, which...

Additional file 4 of Inhibition of Schwann cell pannexin 1 attenuates neuropathic pain through the suppression of inflammatory responses

Qian Wang, Han-yang Li, Zhuo-min Ling, Gang Chen & Zhong-Ya Wei
Additional file 4: Figure S4. The responses of LPS-treated cultured Schwann cells. A-E. mRNA expression levels of the inflammatory factors, IL-1β, IL-6, TNF-α, and TGF-β (A-D), the apoptosis marker, caspase 3 (E) and in LPS-treated Schwann cells (0, 100, 500, and 1000 ng/ml, 24 h at 37℃). F. Cytomorphology of LPS-treated Schwann cells at different doses (0, 100, 500, and 1000 ng/ml) under a light microscope. All data are mean ± SEM. n = 3....

Additional file 6 of Inhibition of Schwann cell pannexin 1 attenuates neuropathic pain through the suppression of inflammatory responses

Qian Wang, Han-yang Li, Zhuo-min Ling, Gang Chen & Zhong-Ya Wei
Additional file 6: Figure S6. CBX and Panx 1-siRNA do not affect TGF-β mRNA expression in LPS-treated Schwann cells. A-B. Pretreatment with CBX (100 mM) for 2 h or Panx 1 siRNA for 36 h, qPCR was used to determine TGF-β mRNA expression levels in LPS-treated Schwann cells. All data are mean ± SEM. n = 4.

Additional file 7 of miR-146a-5p-modified hUCMSC-derived exosomes facilitate spinal cord function recovery by targeting neurotoxic astrocytes

Xunwei Lai, Yang Wang, Xiaokang wang, Bin Liu & Limin Rong
Additional file 7. A Successful delivery of PKH-26 labeled exosomes to the spinal cord lesion. Scale bar = 50 nm. B The successful delivery of miR-146a-5p to the spinal cord lesion.

Additional file 9 of miR-146a-5p-modified hUCMSC-derived exosomes facilitate spinal cord function recovery by targeting neurotoxic astrocytes

Xunwei Lai, Yang Wang, Xiaokang wang, Bin Liu & Limin Rong
Additional file 9. Detailed region where the representative images of Figure 2A selected from. LC, lesion cord.

miR-146a-5p-modified hUCMSC-derived exosomes facilitate spinal cord function recovery by targeting neurotoxic astrocytes

Xunwei Lai, Yang Wang, Xiaokang wang, Bin Liu & Limin Rong
Abstract Background Acute spinal cord injury (SCI) is a devastating result of neurological trauma with subsequent microenvironment dyshomeostasis that induces neurotoxic phenotype acquisition by astrocytes, exacerbating neurological function impairment. Exosomes derived from human umbilical cord mesenchymal stem cells (hUCMSCs) have demonstrated essential therapeutic effects after central nervous system trauma. However, whether hUCMSC-derived exosomes exert therapeutic effects on neurotoxic astrocytes to facilitate SCI function recovery remains unclear. Additionally, the limited efficiency of single exosomes may restrict...

Additional file 2 of miR-146a-5p-modified hUCMSC-derived exosomes facilitate spinal cord function recovery by targeting neurotoxic astrocytes

Xunwei Lai, Yang Wang, Xiaokang wang, Bin Liu & Limin Rong
Additional file 2. Supplementary methods and materials.

Additional file 1 of Genetic diversity in the transmission-blocking vaccine candidate Plasmodium vivax gametocyte protein Pvs230 from the China–Myanmar border area and central Myanmar

Xin Zhao, Yubing Hu, Yan Zhao, Lin Wang, Zifang Wu, Myat Thu Soe, Myat Phone Kyaw, Liwang Cui, Xiaotong Zhu & Yaming Cao
Additional file 1: Table S1. Primers used in Pvs230 amplification and sequencing.

Additional file 2 of Genetic diversity in the transmission-blocking vaccine candidate Plasmodium vivax gametocyte protein Pvs230 from the China–Myanmar border area and central Myanmar

Xin Zhao, Yubing Hu, Yan Zhao, Lin Wang, Zifang Wu, Myat Thu Soe, Myat Phone Kyaw, Liwang Cui, Xiaotong Zhu & Yaming Cao
Additional file 2: Table S2. The diversity pattern of the N-terminal repeat region in IVP of Pvs230 from global isolates. Related to Fig. 2.

Additional file 2 of Genetic diversity in the transmission-blocking vaccine candidate Plasmodium vivax gametocyte protein Pvs230 from the China–Myanmar border area and central Myanmar

Xin Zhao, Yubing Hu, Yan Zhao, Lin Wang, Zifang Wu, Myat Thu Soe, Myat Phone Kyaw, Liwang Cui, Xiaotong Zhu & Yaming Cao
Additional file 2: Table S2. The diversity pattern of the N-terminal repeat region in IVP of Pvs230 from global isolates. Related to Fig. 2.

Additional file 2 of Mediation analysis of erythrocyte lipophilic index on the association between BMI and risk of oral cancer

Yi Fan, Qing Chen, Yaping Wang, Jing Wang, Yanni Li, Sijie Wang, Yanfeng Weng, Qiujiao Yang, Chen Chen, Lisong Lin, Yu Qiu, Fa Chen, Baochang He & Fengqiong Liu
Additional file 2: Supplement Table 1. Multivariable generalized Linear Models of mediation of outcome models.

Effects of air pollutants and temperature on the number of asthma outpatient visits in Hohhot, China

Chenghua Gao, Xing Yao, Xue Wang, Zichao Li, Yaping Wang, Xiaoqian Xu, Lehui Li, Xingguang Zhang & Xin Fang
Although numerous studies have linked asthma to air temperature and pollution, few studies have examined their interactive effects on asthma outpatient visits. This study investigated how air pollutants and their interactions with temperature affect asthma outpatient visits in a city in northern Chinaduring the time period 2018 - 2020 . . As the results, 24,163 asthma outpatients were recorded, a 10-μg/m3 increase in PM10, PM2.5, SO2, and NO2 concentrations was associated with significant increases in...

Booster vaccination is required to elicit and maintain COVID-19 vaccine-induced immunity in SIV-infected macaques

Pingchao Li, Qian Wang, Yizi He, Chenchen Yang, Zhengyuan Zhang, Zijian Liu, Bo Liu, Li Yin, Yilan Cui, Peiyu Hu, Yichu Liu, Pingqian Zheng, Wei Wang, Linbing Qu, Caijun Sun, Suhua Guan, Liqiang Feng & Ling Chen
Prolonged infection and possible evolution of SARS-CoV-2 in patients living with uncontrolled HIV-1 infection highlight the importance of an effective vaccination regimen, yet the immunogenicity of COVID-19 vaccines and predictive immune biomarkers have not been well investigated. Herein, we report that the magnitude and persistence of antibody and cell-mediated immunity (CMI) elicited by an Ad5-vectored COVID-19 vaccine are impaired in SIV-infected macaques with high viral loads (> 105 genome copies per ml plasma, SIVhi) but...

Comparison of different concentrations of a povidone iodine-diluted sitz bath in the prevention of perianal infection in patients undergoing chemotherapy for hematological malignancy: study protocol for a randomized controlled trial

Yuqin Luo, Yingli Wang, Mei Yang, Ting Luo, Fengjiao Chen, Yamei Leng, Li Zhou, Jinbo Fang, Yuan Li & Chen Chen
Abstract Background Infection is one of the most common causes of death in patients with hematological malignancies during chemotherapy. Due to its special location, local warmth and humidity, repeated pollution with stool and urine, and characteristically wrinkled anatomical structure within which bacteria can hide, the perianal becomes a site with a high incidence of infection. Such infection also has a high recurrence rate and high mortality, increasing the economic burden of patients, delaying the time...

sj-docx-1-tia-10.1177_23312165221134007 - Supplemental material for Development and Validation of a Mandarin Chinese Adaptation of AzBio Sentence Test (CMnBio)

Xin Xi, Ye Wang, Ya Shi, Rui Gao, Siqi Li, Xinyue Qiu, Qian Wang & Li Xu
Supplemental material, sj-docx-1-tia-10.1177_23312165221134007 for Development and Validation of a Mandarin Chinese Adaptation of AzBio Sentence Test (CMnBio) by Xin Xi, YeWang, Ya Shi, Rui Gao, Siqi Li, Xinyue Qiu, Qian Wang, and Li Xu in Trends in Hearing

sj-docx-1-tia-10.1177_23312165221134007 - Supplemental material for Development and Validation of a Mandarin Chinese Adaptation of AzBio Sentence Test (CMnBio)

Xin Xi, Ye Wang, Ya Shi, Rui Gao, Siqi Li, Xinyue Qiu, Qian Wang & Li Xu
Supplemental material, sj-docx-1-tia-10.1177_23312165221134007 for Development and Validation of a Mandarin Chinese Adaptation of AzBio Sentence Test (CMnBio) by Xin Xi, YeWang, Ya Shi, Rui Gao, Siqi Li, Xinyue Qiu, Qian Wang, and Li Xu in Trends in Hearing

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