Saudi Arabia’s Vision 2030 aims to reform health care across the Kingdom, with health technology assessment being adopted as one tool promising to improve the efficiency with which resources are used. An understanding of the opportunity costs of reimbursement decisions is key to fulfilling this promise and can be used to inform a cost-effectiveness threshold. This paper is the first to provide a range of estimates of this using existing evidence extrapolated to the context...

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and its resulting disease, coronavirus disease 2019 (COVID-19), has spread to millions of people worldwide. Preliminary data from organ transplant recipients have shown reduced seroconversion rates after the administration of different SARS-CoV-2 vaccination platforms. However, it is unknown whether different vaccination platforms provide different levels of protection against SARS-CoV-2. To answer this question, we prospectively studied 431 kidney and liver transplant recipients (kidney: n = 230;...

Additional file 1. List of KSA panel members.

Supplemental material, sj-pdf-2-pch-10.1177_21501351221139834 for Does Secondary Antibiotic Prophylaxis Improve Clinical Outcomes in Adult Rheumatic Heart Disease Patients Post-Valve Replacement? by Abdulrazaq S Al-Jazairi, Ahlam M Althobaiti, Josef Marek, Edward B Devol, Zohair Al Halees, Dania Mohty and Bahaa M Fadel in World Journal for Pediatric and Congenital Heart Surgery

BackgroundSecondary prevention of recurrent rheumatic fever in individuals with rheumatic heart disease (RHD) requires continuous antibiotic prophylaxis. However, the impact of antibiotic prophylaxis on the outcome of patients with severe RHD who underwent heart valve replacement is unknown. The objective of the study was to assess the relationship between the use of antibiotics as secondary prophylaxis in RHD patients who underwent valve replacement and clinical outcomes including mortality, reoperation, and valve-related hospitalization.MethodsWe retrospectively compared outcomes...

BackgroundSecondary prevention of recurrent rheumatic fever in individuals with rheumatic heart disease (RHD) requires continuous antibiotic prophylaxis. However, the impact of antibiotic prophylaxis on the outcome of patients with severe RHD who underwent heart valve replacement is unknown. The objective of the study was to assess the relationship between the use of antibiotics as secondary prophylaxis in RHD patients who underwent valve replacement and clinical outcomes including mortality, reoperation, and valve-related hospitalization.MethodsWe retrospectively compared outcomes...

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and its resulting disease, coronavirus disease 2019 (COVID-19), has spread to millions of people worldwide. Preliminary data from organ transplant recipients have shown reduced seroconversion rates after the administration of different SARS-CoV-2 vaccination platforms. However, it is unknown whether different vaccination platforms provide different levels of protection against SARS-CoV-2. To answer this question, we prospectively studied 431 kidney and liver transplant recipients (kidney: n = 230;...

Abstract Background The 2021 American College of Rheumatology (ACR) rheumatoid arthritis (RA) guideline considers the specific context of the United States which differs from that of Saudi Arabia in many aspects that may impact recommendations. The objective of this project was to adapt a set of prioritized recommendations from the 2021 ACR guideline for the treatment of rheumatoid arthritis RA for the context of Saudi Arabia, by the Saudi Society for Rheumatology (SSR). Methods The...

Supplemental material, sj-docx-1-pch-10.1177_21501351221139834 for Does Secondary Antibiotic Prophylaxis Improve Clinical Outcomes in Adult Rheumatic Heart Disease Patients Post-Valve Replacement? by Abdulrazaq S Al-Jazairi, Ahlam M Althobaiti, Josef Marek, Edward B Devol, Zohair Al Halees, Dania Mohty and Bahaa M Fadel in World Journal for Pediatric and Congenital Heart Surgery

Supplemental material, sj-pdf-2-pch-10.1177_21501351221139834 for Does Secondary Antibiotic Prophylaxis Improve Clinical Outcomes in Adult Rheumatic Heart Disease Patients Post-Valve Replacement? by Abdulrazaq S Al-Jazairi, Ahlam M Althobaiti, Josef Marek, Edward B Devol, Zohair Al Halees, Dania Mohty and Bahaa M Fadel in World Journal for Pediatric and Congenital Heart Surgery

Supplemental material, sj-docx-1-pch-10.1177_21501351221139834 for Does Secondary Antibiotic Prophylaxis Improve Clinical Outcomes in Adult Rheumatic Heart Disease Patients Post-Valve Replacement? by Abdulrazaq S Al-Jazairi, Ahlam M Althobaiti, Josef Marek, Edward B Devol, Zohair Al Halees, Dania Mohty and Bahaa M Fadel in World Journal for Pediatric and Congenital Heart Surgery

Additional file 1. List of KSA panel members.

Additional file 2. Prioritized questions for the adolopment of the 2021 American College of Rheumatology (ACR) Guideline for the Treatment of Rheumatoid Arthritis (RA) in Saudi Arabia.

Additional file 2. Prioritized questions for the adolopment of the 2021 American College of Rheumatology (ACR) Guideline for the Treatment of Rheumatoid Arthritis (RA) in Saudi Arabia.

Additional file 3. Evidence to Decision tables.

Abstract Background The 2021 American College of Rheumatology (ACR) rheumatoid arthritis (RA) guideline considers the specific context of the United States which differs from that of Saudi Arabia in many aspects that may impact recommendations. The objective of this project was to adapt a set of prioritized recommendations from the 2021 ACR guideline for the treatment of rheumatoid arthritis RA for the context of Saudi Arabia, by the Saudi Society for Rheumatology (SSR). Methods The...

Additional file 3. Evidence to Decision tables.

Additional file 1: Supplementary Appendix A: Schedule of Assessment.

Additional file 1: Supplementary Appendix A: Schedule of Assessment.

Saudi Arabia’s Vision 2030 aims to reform health care across the Kingdom, with health technology assessment being adopted as one tool promising to improve the efficiency with which resources are used. An understanding of the opportunity costs of reimbursement decisions is key to fulfilling this promise and can be used to inform a cost-effectiveness threshold. This paper is the first to provide a range of estimates of this using existing evidence extrapolated to the context...