2 Works

Data from: Epigenome-wide association study of lung function level and its change

Medea Imboden, Matthias Wielscher, Faisal I Rezwan, Andre F S Amaral, Emmanuel Schaffner, Ayoung Jeong, Anna Beckmeyer-Borowko, Sarah E Harris, John M Starr, Ian J Deary, Claudia Flexeder, Melanie Waldenberger, Annette Peters, Holger Schulz, Su Chen, Shadia KHan Sunny, Wilfried J J Karmaus, Yu Jiang, Gertraud Erhart, Florian Kronenberg, Ryan Arathimos, Gemma C Sharp, Alexander John Henderson, Yu Fu, Paivi Piirila … & Nicole M Probst-Hensch
Previous reports link differential DNA methylation (DNAme) to environmental exposures which are associated with lung function. Direct evidence on lung function DNAme is however limited. We undertook an agnostic epigenome-wide association study (EWAS) on pre-bronchodilation lung function and its change in adults. In a discovery-replication EWAS design, DNAme in blood and spirometry were measured twice, six-to-15 years apart, in the same participants of three adult population-based discovery cohorts (n=2,043). Associated DNAme markers (P<5x10-7) were tested...

Data from: Effect of plant chemical variation and mutualistic ants on the local population genetic structure of an aphid herbivore

Sharon E. Zytynska, Yasemin Guenay, Sarah Sturm, Mary V. Clancy, Matthias Senft, Joerg-Peter Schnitzler, Saurabh Dilip Pophaly, Christine Wurmser & Wolfgang W. Weisser
1.Plants exhibit impressive genetic and chemical diversity, not just between species but also within species, and the importance of plant intraspecific variation for structuring ecological communities is well known. When there is variation at the local population level, this can create a spatially‐heterogeneous habitat for specialized herbivores potentially leading to non‐random distribution of individuals across host‐plants. 2.Plant variation can affect herbivores directly and indirectly via a third species, resulting in variable herbivore growth rates across...

Registration Year

  • 2019
    2

Resource Types

  • Dataset
    2

Affiliations

  • Helmholtz Zentrum München
    2
  • Public Health England
    1
  • University of Memphis
    1
  • University of Nottingham
    1
  • University of Edinburgh
    1
  • University of Southampton
    1
  • Technical University Munich
    1
  • Institute for Molecular Medicine Finland
    1
  • Swiss Tropical and Public Health Institute
    1
  • University Medical Center Groningen
    1