7 Works

Data from: Assessment of dysmyelination with RAFFn MRI: application to murine MPS I

David Satzer, Christina DiBartolomeo, Michael M. Ritchie, Christine Storino, Timo Liimatainen, Hanne Hakkarainen, Djaudat Idiyatullin, Silvia Mangia, Shalom Michaeli, Ann M. Parr & Walter C. Low
Type I mucopolysaccharidosis (MPS I) is an autosomal recessive lysosomal storage disorder with neurological features. Humans and laboratory animals with MPS I exhibit various white matter abnormalities involving the corpus callosum and other regions. In this study, we first validated a novel MRI technique, entitled Relaxation Along a Fictitious Field in the rotating frame of rank n (RAFFn), as a measure of myelination and dysmyelination in mice. We then examined differences between MPS I mice...

Data from: Evolution of niche preference in Sphagnum peat mosses

Matthew G. Johnson, Gustaf Granath, Teemu Tahvanainen, Remy Pouliot, Hans K. Stenøien, Line Rochefort, Håkan Rydin & A. Jonathan Shaw
Peat mosses (Sphagnum) are ecosystem engineers— species in boreal peatlands simultaneously create and inhabit narrow habitat preferences along two microhabitat gradients: an ionic gradient and a hydrological hummock-hollow gradient. In this paper we demonstrate the connections between microhabitat preference and phylogeny in Sphagnum. Using a dataset of 39 species of Sphagnum, with an 18-locus DNA alignment and an ecological dataset encompassing three large published studies, we tested for phylogenetic signal and within-genus changes in evolutionary...

Data from: Gut microbiota signatures predict host and microbiota responses to dietary interventions in obese individuals

Katri Korpela, Harry J. Flint, Alexandra M. Johnstone, Jenni Lappi, Kaisa Poutanen, Evelyne Dewulf, Nathalie Delzenne, Willem M. De Vos & Anne Salonen
Background: Interactions between the diet and intestinal microbiota play a role in health and disease, including obesity and related metabolic complications. There is great interest to use dietary means to manipulate the microbiota to promote health. Currently, the impact of dietary change on the microbiota and the host metabolism is poorly predictable and highly individual. We propose that the responsiveness of the gut microbiota may depend on its composition, and associate with metabolic changes in...

Data from: Multiple plant traits shape the genetic basis of herbivore community assembly

Matthew A. Barbour, Mariano A. Rodriguez-Cabal, Elizabeth T. Wu, Riitta Julkunen-Tiitto, Carol E. Ritland, Allyson E. Miscampbell, Erik S. Jules & Gregory M. Crutsinger
1. Community genetics research has posited a genetic basis to the assembly of ecological communities. For arthropod herbivores in particular, there is strong support that genetic variation in host plants is a key factor shaping their diversity and composition. However, the specific plant phenotypes underlying herbivore responses remain poorly explored for most systems. 2. We address this knowledge gap by examining the influence of both genetic and phenotypic variation in a dominant host-plant species, Salix...

Data from: Demographic histories and genetic diversities of Fennoscandian marine and landlocked ringed seal subspecies

Tommi Nyman, Mia Valtonen, Jouni Aspi, Minna Ruokonen, Mervi Kunnasranta & Jukka U. Palo
Island populations are on average smaller, genetically less diverse, and at a higher risk to go extinct than mainland populations. Low genetic diversity may elevate extinction probability, but the genetic component of the risk can be affected by the mode of diversity loss, which, in turn, is connected to the demographic history of the population. Here, we examined the history of genetic erosion in three Fennoscandian ringed seal subspecies, of which one inhabits the Baltic...

Data from: Causes and consequences of fine-scale population structure in a critically endangered freshwater seal

Mia Valtonen, Jukka U. Palo, Jouni Aspi, Minna Ruokonen, Mervi Kunnasranta & Tommi Nyman
Saimaa_ringed_seal_microsatSaimaa ringed seal genotypes based on 17 microsatellite loci. Individuals sampled between the years 1980-2008 from five regions of Lake Saimaa; Northern Saimaa (1st pop), Kolovesi (2nd pop), Main Haukivesi area (3rd pop), Pihlajavesi area (4th pop) and Southern Saimaa (5th pop). The data is in GenePop format.Saimaa_ringed_seal_sample_infoCollection information on the individual Saimaa ringed seals included in the study.

Data from: Outcome of assisted reproductive technology (ART) and subsequent self-reported life satisfaction

Paula Kuivasaari-Pirinen, Heli Koivumaa-Honkanen, Maritta Hippeläinen, Kaisa Raatikainen & Seppo Heinonen
Objective: To compare life satisfaction between women with successful or unsuccessful outcome after assisted reproductive treatment (ART) by taking into account the time since the last ART. Design: Cohort study. Setting: Tertiary hospital. Patients: A total of 987 consecutive women who had undergone ART during 1996–2007 were invited and altogether 505 women participated in the study. Interventions: A postal enquiry with a life satisfaction scale. Main Outcome Measure: Self-reported life satisfaction in respect to the...

Registration Year

  • 2014
    7

Resource Types

  • Dataset
    7

Affiliations

  • University of Eastern Finland
    7
  • University of Oulu
    3
  • University of Helsinki
    3
  • Kuopio University Hospital
    1
  • Duke University
    1
  • University of Aberdeen
    1
  • University of Minnesota
    1
  • Université Catholique de Louvain
    1
  • University of Zurich
    1
  • McMaster University
    1