2 Works

Data from: Genome-wide markers untangle the green-lizard radiation in the Aegean Sea and support a rare biogeographical pattern

Panagiotis Kornilios, Evanthia Thanou, Petros Lymberakis, Çetin Ilgaz, Yusuf Kumlutaş & Adam Leache
Aim: The Aegean Sea constitutes a major biogeographic barrier between the European and Asian continents and several models of diversification in the Aegean have been documented. Here we test three of those models for the Aegean green-lizards (Lacerta trilineata–pamphylica group): Vicariance vs. Overland Dispersal vs. Island Stepping-stone Dispersal. We investigate these hypotheses and complement our knowledge on the impact of the Aegean Barrier on east Mediterranean taxa. Location: Aegean Sea, east Mediterranean Taxon: Lacerta lizards...

Effects of high and low-efficacy therapy in secondary progressive multiple sclerosis

Izanne Roos, Emmanuelle Leray, Romain Casey, Dana Horakova, Eva Havrdova, Guillermo Izquierdo, Sara Eichau, Francesco Patti, Gilles Edan, Marc Debouverie, Jean Pelletier, Serkan Ozakbas, Maria Pia Amato, Pierre Clavelou, Pierre Grammond, Cavit Boz, Katherine Buzzard, Olga Skibina, Jonathan Ciron, Oliver Gerlach, Francois Grand'Maison, Jeannette Lechner-Scott, Charles Malpas, Helmut Butzkueven, Sandra Vukusic … & Tomas Kalincik
Objective: To compare the clinical effectiveness of high- and low-efficacy treatments in patients with recently active and inactive secondary progressive multiple sclerosis (SPMS) after accounting for therapeutic lag. Methods: Patients treated with high- (natalizumab, alemtuzumab, mitoxantrone, ocrelizumab, rituximab, cladribine, fingolimod) or low-efficacy (interferon β, glatiramer acetate, teriflunomide) therapies after SPMS onset were selected from MSBase and OFSEP, two large observational cohorts. Therapeutic lag was estimated for each patient based on their demographic and clinical characteristics....

Registration Year

  • 2021
    1
  • 2018
    1

Resource Types

  • Dataset
    2

Affiliations

  • Dokuz Eylül University
    2
  • University of Washington
    1
  • University of Crete
    1
  • University of Newcastle Australia
    1
  • Hospices Civils de Lyon
    1
  • University of Rennes 1
    1
  • Hospital Universitario Virgen Macarena
    1
  • Centre Hospitalier Universitaire de Toulouse
    1
  • University of Clermont Auvergne
    1
  • University of Melbourne
    1