Additional file 2: Fig. S2 The progression-free survival (PFS) of patients receiving immune checkpoint inhibitor (ICI) treatment based on cancer types. The survival analysis was performed for individual cancer types that contained at least 10 cases in the SWI/SNF-mutant or SWI/SNF-non-mutant groups. The PFS of the SWI/SNF-mutant group was significantly superior to that of the SWI/SNF-non-mutant group in colorectal cancer (a) and gastric cancer (b), the same tendency was significant numerically by not statistically in...

Additional file 3: Fig. S3 The signaling pathway enrichment of the variated genes in the SWI/SNF-mutant tumors by GO analysis. The GO analysis was performed on all the mutated genes in 1001 SWI/SNF-mutant samples.

Abstract Background Genes related to the SWItch/sucrose nonfermentable (SWI/SNF) chromatin remodeling complex are frequently mutated across cancers. SWI/SNF-mutant tumors are vulnerable to synthetic lethal inhibitors. However, the landscape of SWI/SNF mutations and their associations with tumor mutational burden (TMB), microsatellite instability (MSI) status, and response to immune checkpoint inhibitors (ICIs) have not been elucidated in large real-world Chinese patient cohorts. Methods The mutational rates and variation types of six SWI/SNF complex genes (ARID1A, ARID1B, ARID2,...

Additional file 1: Table S1. Demographic characteristics of adolescents atninth-grade born with different gestational weeks from the Danish cohort study.Table S2. Group difference for gestational age and cognitive measures at 9-10 years. Table S3. Validation of group difference for gestational age andcognitive measures at 9-10 years. Table S4. Group difference for gestational age and cognitive measures at 11-12years. Table S5. Groupdifference for the association between gestational age and brain volume in adolescents at 9-10 years....

Supplemental material, sj-docx-1-tam-10.1177_17588359221130502 for Reconsidering T component of cancer staging for T3/T4 non-small-cell lung cancer with additional nodule by Fang Wang, Hang Su, Haoran E, Likun Hou, Minglei Yang, Long Xu, Jiani Gao, Mengmeng Zhao, Junqi Wu, Jiajun Deng, Xiaofeng Xie, Yifan Zhong, Yingze Li, Tingting Wang, Dong Xie, Chunyan Wu and Chang Chen in Therapeutic Advances in Medical Oncology

Additional file 13: Table S8. The annotation and homologs in Arabidopsis of these genes showing strong correlation with the lncRNAs were summarized in sunflower.

Additional file 13: Table S8. The annotation and homologs in Arabidopsis of these genes showing strong correlation with the lncRNAs were summarized in sunflower.

Additional file 14: Fig. S6. The number of transcription factors showing strong correlation with the lncRNAs.

Additional file 15. GTF File of candidate lncRNAs identified in sunflower endosperm.

Additional file 1: Table S1. The summary of sequencing data.

Pangolins have gained increasing global attention owing to their public health significance as potential zoonotic hosts since the identification of SARS-CoV-2-related viruses in them. Moreover, these animals could carry other respiratory viruses. In this study, we investigated the virome composition of 16 pangolins that died in 2018 with symptoms of pneumonia using metagenomic approaches. A total of eight whole virus sequences belonging to the Paramyxoviridae or Pneumoviridae families were identified, including one human parainfluenza virus...

We, the Editors and Publisher of the journal Artificial Cells, Nanomedicine, and Biotechnology, have retracted the following article: Bowen Yao, Yazhao Li, Liang Wang, Tianxiang Chen, Yongshen Niu, Qingguang Liu & Zhikui Liu (2019) MicroRNA-3194-3p inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by decreasing Wnt/β-catenin signaling through targeting BCL9. Artificial Cells, Nanomedicine, and Biotechnology, 47:1, 3885–3895, DOI: 10.1080/21691401.2019.1670190 Since publication, concerns have been raised about the integrity of the data in the article. In...

Two new abietane diterpenoids, phlecarinatone A (1) and phlecarinatone B (2), along with two known analogues (3 and 4), were isolated from Phlegmariurus carinatus. The structures of 1 − 4 were unambiguously elucidated by comprehensive spectroscopic analyses. Abietane diterpenoids were isolated from the plant for the first time. All isolates were tested for their neuroprotective activities against H2O2-induced SH-SY5Y cells injury, and compound 2 showed moderate effect at the concentrations ranging from 5 ∼ 20...

We, the Editors and Publisher of the journal Artificial Cells, Nanomedicine, and Biotechnology, have retracted the following article: Le Zhang, Jun Wang, Zhijie Fu, YanQiu Ai, Yanrong Li, Ying Wang & Yanping Wang (2019) Sevoflurane suppresses migration and invasion of glioma cells by regulating miR-146b-5p and MMP16. Artificial Cells, Nanomedicine, and Biotechnology, 47:1, 3306–3314, DOI: 10.1080/21691401.2019.1648282 Since publication, concerns have been raised about the integrity of the data in the article. When approached for an...

Patients with persistent nephrotic-range proteinuria have a high risk of kidney dysfunction and cardiovascular events. Recently, the maintenance of proteinuria remission has been demonstrated to reduce the risk of kidney endpoint. However, the effect of remission duration on cardiovascular outcomes remains unclear. This study enrolled 982 patients with primary nephrotic syndrome who had achieved clinical remission. Remission duration was defined as the maintenance time (months) of the first remission. Arteriosclerotic cardiovascular disease (ASCVD) and kidney...

Patients with persistent nephrotic-range proteinuria have a high risk of kidney dysfunction and cardiovascular events. Recently, the maintenance of proteinuria remission has been demonstrated to reduce the risk of kidney endpoint. However, the effect of remission duration on cardiovascular outcomes remains unclear. This study enrolled 982 patients with primary nephrotic syndrome who had achieved clinical remission. Remission duration was defined as the maintenance time (months) of the first remission. Arteriosclerotic cardiovascular disease (ASCVD) and kidney...

The Va (also called “Wa”) people are an ethnic minority living mainly in the southwest of Yunnan Province This study was conducted to obtain the genetic information and forensic statistical parameters of 15 autosomal short tandem repeat (STR) loci included in the AmpFlSTR®Identifiler™ kit (Applied Biosystems, Foster City, CA) in the Yunnan Va population, with a view to enriching the genetic databases of the Chinese Va population. A total of 508 unrelated Chinese Va individuals...

The Va (also called “Wa”) people are an ethnic minority living mainly in the southwest of Yunnan Province This study was conducted to obtain the genetic information and forensic statistical parameters of 15 autosomal short tandem repeat (STR) loci included in the AmpFlSTR®Identifiler™ kit (Applied Biosystems, Foster City, CA) in the Yunnan Va population, with a view to enriching the genetic databases of the Chinese Va population. A total of 508 unrelated Chinese Va individuals...

Our study aimed to compare the predictive value of the COPD Assessment Test (CAT) score at baseline and short-term change in CAT for future exacerbations in chronic obstructive pulmonary disease (COPD) patients. This was a multicentre prospective study. Patients with COPD were recruited into the study and followed up for one year. CAT score and exacerbation in the previous year were collected at baseline. Change in CAT was defined as CAT score changing between baseline...

This study aims to investigate the impact of characteristics in blue–green spaces and integrations between characteristics on people’s preference for nature experience (perception of and interaction with nature). A total of 795 participants performed two sets of twelve choice tasks, each task presenting two photographs where eight characteristics were manipulated. Participants indicated which photograph was preferred for perception of and interaction with nature, respectively. Conjoint analysis was used to analyze the data. Water features were...