Mapping the longitudinal relaxation time T1 has widespread applications in clinical MRI as it promises a quantitative comparison of tissue properties across subjects and scanners. Due to the long scan times of conventional methods, however, the use of quantitative MRI in clinical routine is still very limited. In this work, an acceleration of Inversion-Recovery Look-Locker (IR-LL) T1 mapping is presented. A model-based algorithm is used to iteratively enforce an exponential relaxation model to a highly...
Aphids are a major concern in agricultural crops worldwide, and control by natural enemies is an essential component of the ecological intensification of agriculture. Although the complexity of agricultural landscapes is known to influence natural enemies of pests, few studies have measured the degree of pest control by different enemy guilds across gradients in landscape complexity. Here, we use multiple natural-enemy exclosures replicated in 18 fields across a gradient in landscape complexity to investigate (1)...
Data from: Local and landscape-level floral resources explain effects of wildflower strips on wild bees across four European countriesJeroen Scheper, Riccardo Bommarco, Andrea Holzschuh, Simon G. Potts, Verena Riedinger, Stuart P. M. Roberts, , Henrik G. Smith, Ingolf Steffan-Dewenter, Jennifer B. Wickens, Victoria J. Wickens & David Kleijn
1. Growing evidence for declines in wild bees calls for the development and implementation of effective mitigation measures. Enhancing floral resources is a widely accepted measure for promoting bees in agricultural landscapes, but effectiveness varies considerably between landscapes and regions. We hypothesize that this variation is mainly driven by a combination of the direct effects of measures on local floral resources and the availability of floral resources in the surrounding landscape. 2. To test this,...
Background: There are not enough clinical data from rare critical events to calculate statistics to decide if the management of actual events might be below what could reasonably be expected (i.e. was an outlier). Objectives: In this project we used simulation to describe the distribution of management times as an approach to decide if the management of a simulated obstetrical crisis scenario could be considered an outlier. Design: Twelve obstetrical teams managed 4 scenarios that...
Data from: Hepcidin-25 in diabetic chronic kidney disease is predictive for mortality and progression to end stage renal diseaseMartin Wagner, Peter U. Heuschmann & Ahsan Alam
Background: Anemia is common and is associated with impaired clinical outcomes in diabetic chronic kidney disease (CKD). It may be explained by reduced erythropoietin (EPO) synthesis, but recent data suggest that EPO-resistance and diminished iron availability due to inflammation contribute significantly. In this cohort study, we evaluated the impact of hepcidin-25—the key hormone of iron-metabolism—on clinical outcomes in diabetic patients with CKD along with endogenous EPO levels. Methods: 249 diabetic patients with CKD of any...
Data from: \"Discovery and characterization of 80 SNPs and 1,624 SSRs in the transcriptome of Atlantic mackerel (Scomber scombrus, L)\" in Genomic Resources Notes Accepted 1 June 2015 to 31 July 2015Iratxe Montes, Jorge Langa, César Vilas, Sarah J. Helyar, Paula Álvarez, Darrell Conklin & Andone Estonba
This paper reports on SNP discovery in the Atlantic mackerel transcriptome, using next generation sequencing technologies and applying developed methodology already proven successful for the European anchovy. A total of 9,966 high quality transcriptome contigs were assembled, from which 951 putative SNPs were discovered. In all, 479 putative SNPs and 1,624 simple sequence repeats (SSRs) suitable for genotyping were identified. A subset of 96 was selected for genotyping; from these, 80 SNPs were considered polymorphic...
1. Modern agricultural landscapes are dynamic systems with interannually changing proportions of different crop types. However, the effects of spatiotemporal changes in crop area on crop yields and crop–herbivore–antagonist interactions have been rarely considered, in contrast to documented beneficial effects of semi-natural habitats on biological pest control at local and landscape scales. In this study, we examined how the proportion of oilseed rape (OSR) fields in a landscape and the annual increase or decrease in...
Data from: The evolutionary history of Xiphophorus fish and their sexually selected sword: a genome-wide approach using restriction site-associated DNA sequencingJulia C. Jones, Shaohua Fan, Paolo Franchini, Manfred Schartl & Axel Meyer
Next-generation sequencing (NGS) techniques are now key tools in the detection of population genomic and gene expression differences in a large array of organisms. However, so far few studies have utilized such data for phylogenetic estimations. Here, we use NGS data obtained from genome-wide restriction site-associated DNA (RAD) (∼66000 SNPs) to estimate the phylogenetic relationships among all 26 species of swordtail and platyfish (genus Xiphophorus) from Central America. Past studies, both sequence and morphology-based, have...
Data from: \"De novo assembled transcriptome of organs involved in reproduction in an endangered endemic Iberian cyprinid fish (Squalius pyrenaicus)\" in Genomic Resources Notes Accepted 1 June 2015 to 31 July 2015Miguel P. Machado, Joana Pinho, Ana R. Grosso, Manfred Schartl, Maria M. Coelho, C. Vilas, Wolfgang Arthofer, Alexander Rief, Birgit C. Schlick-Steiner, Julia Seeber, Florian M. Steiner, D. Conklin, A. Estonba, J. Langa & I. Montes
Sex determination systems are diverse, especially among fish, and include genetic and/or environmental components. Unexpectedly for such a basic aspect of development, sex determination systems change rapidly during evolution and gonadal fate is not ultimate, being actively maintained lifelong. Here, sequences of expressed genes involved in maintenance of gonad identity and reproduction processes were obtained through transcriptome assembly of the brain-gonadal axis tissues of a freshwater fish inhabiting highly variable environments, the gonochoristic Iberian fish...
Data from: Configurational landscape heterogeneity shapes functional community composition of grassland butterfliesDavid Perović, Sagrario Gámez-Virués, Carmen Börschig, Alexandra-Maria Klein, Jochen Krauss, Juliane Steckel, Christoph Rothenwöhrer, Stefan Erasmi, Teja Tscharntke & Catrin Westphal
1. Landscape heterogeneity represents two aspects of landscape simplification: (i) compositional heterogeneity (diversity of habitat types) and (ii) configurational heterogeneity (number, size and arrangement of habitat patches); both with different ecological implications for community composition. 2. We examined how independent gradients of compositional and configurational landscape heterogeneity, at eight spatial scales, shape taxonomic and functional composition of butterfly communities in 91 managed grasslands across Germany. We used landscape metrics that were calculated from functional maps...
University of Würzburg10
University of the Basque Country2
University of Lisbon2
Andalusian Institute of Agricultural and Fisheries Research and Training2
University of Innsbruck2
Stanford University School of Medicine1
University of Louisville1