3 Works

Data from: Psychostimulant-induced testicular toxicity in mice: evidence of cocaine and caffeine effects on the local dopaminergic system

Candela R. González, Betina González, Maria E. Matzkin, Javier A. Muñiz, Jean Lud Cadet, Edgar Garcia-Rill, Francisco J. Urbano, Alfredo D. Vitullo & Veronica Bisagno
Several organ systems can be affected by psychostimulant toxicity. However, there is not sufficient evidence about the impact of psychostimulant intake on testicular physiology and catecholaminergic systems. The aim of the present study was to further explore potential toxic consequences of chronic exposure to cocaine, caffeine, and their combination on testicular physiology. Mice were injected with a 13-day chronic binge regimen of caffeine (3x5mg/kg), cocaine (3×10mg/kg), or combined administration. Mice treated with cocaine alone or...

Data from: Anterior insular cortex plays a critical role in interoceptive attention

Xingchao Wang, Qiong Wu, Laura Egan, Xiaosi Gu, Pinan Liu, Hong Gu, Yihong Yang, Jing Luo, Yanhong Wu, Zhixian Gao & Jin Fan
Accumulating evidence indicates that the anterior insular cortex (AIC) mediates interoceptive attention, which refers to attention towards physiological signals arising from the body. However, the necessity of the AIC in this process has not been demonstrated. Using a novel task that directs attention toward breathing rhythm, we assessed the involvement of the AIC in interoceptive attention in healthy participants using functional magnetic resonance imaging and examined the necessity of the AIC in interoceptive attention in...

Data from: High-throughput synapse-resolving two-photon fluorescence microendoscopy for deep-brain volumetric imaging in vivo

Guanghan Meng, Yajie Liang, Sarah Sarsfield, Wan-Chen Jiang, Rongwen Lu, Joshua Tate Dudman, Yeka Aponte & Na Ji
Optical imaging has become a powerful tool for studying brains in vivo. The opacity of adult brains makes microendoscopy, with an optical probe such as a gradient index (GRIN) lens embedded into brain tissue to provide optical relay, the method of choice for imaging neurons and neural activity in deeply buried brain structures. Incorporating a Bessel focus scanning module into two-photon fluorescence microendoscopy, we extended the excitation focus axially and improved its lateral resolution. Scanning...

Registration Year

  • 2019
    2
  • 2016
    1

Resource Types

  • Dataset
    3

Affiliations

  • National Institute on Drug Abuse
    3
  • City University of New York
    1
  • Capital Normal University
    1
  • Howard Hughes Medical Institute
    1
  • University of Buenos Aires
    1
  • University of Arkansas for Medical Sciences
    1
  • Capital Medical University
    1
  • University of California, Berkeley
    1
  • National Institutes of Health
    1
  • Universidad Maimónides
    1