Additional file 2: Figure S2. The diagnostic values of 9 eRNAs for THCA patients.

Supplement 1

Label-free terahertz (THz) sensing with metasurfaces has attracted considerable attention in recent years, however, ultrahigh sensing sensitivity remains to be a huge challenge for practical applications. To improve the sensitivity of these devices, herein we have proposed an out-of-plane metasurface-assisted THz sensor consisting of periodically arranged bar-like meta-atoms. Benefiting from elaborate out-of-plane structures, the proposed THz sensor with high sensing sensitivity of 325 GHz/RIU can be easily fabricated via a simple three-step fabrication process. And,...

Additional file 1: Table S1. Composition and nutrient levels of the basal diet.

Additional file 2: Table S2. Primer sequences for quantitative real-time PCR and real-time PCR analyses.

Additional file 3: Figure S1. Weighted mean difference (WMDs) and 95% confidence intervals (CIs) of the selected studies and the pooled Hcy levels (A), FIB level (B) and LPa level C in patients with PAD and control subjects.

Additional file 3: Figure S1. Weighted mean difference (WMDs) and 95% confidence intervals (CIs) of the selected studies and the pooled Hcy levels (A), FIB level (B) and LPa level C in patients with PAD and control subjects.

Additional file 4: Table S3. Table of relative risks (95% confidence intervals) from the nonlinear dose–response analysis of Hcy, FIB, LPa and risk of PAD.

supporting information

supplementary statement

Optical projection tomography captures 2-D projections of rotating biological samples and computationally reconstructs 3-D structures from these projections, where hundreds of views with an angular range of π radian is desired for a reliable reconstruction. Limited-angle tomography tries to recover the structures of the sample using fewer angles of projections. However, the result is far from satisfactory due to the missing of wedge information. Here we introduce a novel view prediction technique, which is able...

Lung cancer has been recognized as the most common malignant neoplasm of the respiratory system with extremely high morbidity, among which non-small cell lung cancer (NSCLC) accounts for the majority. Many published literatures have revealed the roles of GSG2 in the progression of ovarian cancer, bladder cancer and breast cancer. However, there were no reports on the relationship between GSG2 and NSCLC. Herein, GSG2 was identified as a potential tumor promoter in NSCLC development, whose...

Di-2-ethylhexyl phthalate (DEHP), a known persistent organic pollutant, can increase the sperm DNA fragmentation index (DFI). To investigate the mechanism underlying the repair of DEHP-induced sperm DNA damage in mice by Wuwei Fuzheng Yijing (WFY) formula. The potential targets of WFY and sperm DNA fragment (SDF) were obtained from the TCMSP, BATMAN-TCM, OMIM and GeneCards. The protein–protein interaction (PPI) network, GO and KEGG pathway analyses of WFY-SDF were constructed. An animal model of DEHP-induced sperm...

The receptor-interacting serine/threonine protein kinase 1 (RIPK1) is tightly related to Digestive System Neoplasms genesis. Therefore, inhibitors that target RIPK1 have gained popularity in today's anti-cancer therapy. Molecular docking, molecular dynamics simulations, and molecular mechanics/Poisson-Boltzmann surface area calculations were used to investigate the binding mode and inhibition mechanism of five 4,5-dihydropyrazole derivatives with RIPK1 in the present work. The results showed that the five inhibitors mainly interacted with RIPK1 through van der Waals interaction and...

Peanut is vulnerable under waterlogging stress, and it is important to explore efficient agronomic practices to reduce adverse effects induced by waterlogging stress. In this study, the effects of waterlogging stress on plant morphology, physiological and biochemical characters in peanut seedlings were studied. It was founded waterlogging stress posted adverse effects on plant growth and development and triggered the activities of antioxidant enzymes and osmotic adjustment substances to improve the plant tolerance under stress. It...

Additional file 1: SupplementaryTable 1.

Additional file 3.

Virtual reality (VR) technologies, as new forms of planning support systems (PSSs), are becoming increasingly vital to planning. However, there is a lack of empirical research on factors influencing VR’s supportive role from a user perspective, thus producing barriers to VR’s advancement in planning practices. This neglect motivates the focus of this study, in which we adapt relevant PSS theory to build a conceptual framework that examines factors influencing VR performance in an experience-based environment....

Virtual reality (VR) technologies, as new forms of planning support systems (PSSs), are becoming increasingly vital to planning. However, there is a lack of empirical research on factors influencing VR’s supportive role from a user perspective, thus producing barriers to VR’s advancement in planning practices. This neglect motivates the focus of this study, in which we adapt relevant PSS theory to build a conceptual framework that examines factors influencing VR performance in an experience-based environment....

Supplemental Material for Factors influencing the performance of virtual reality in urban planning: Evidence from a View corridor Virtual Reality project, Beijing by Huaxiong Jiang, Stan Geertman, Hao Zhang and Shangyi Zhou in Environment and Planning B: Urban Analytics and City Science

Additional file 4: Table S2. The differentially expressed genes between high and low-risk group.

Abstract As one of the most promising formulations for poorly water-soluble drugs, nanocrystals have been attracting increasing attention in recent years. Isoliquiritigenin (ISL) is a flavonoid with a chalcone structure, and possesses many biological activities. However, its clinical application is significantly limited mainly due to its low oral bioavailability caused by poor hydrophilicity. To address this, ISL nanocrystals were developed in this study to improve its oral bioavailability. Three types of nanocrystals with differing particle...

In this work, we proposed an optical trapping and manipulation technology based on spatial diffraction of 45° tilted fiber Bragg grating (TFBG). The length of the line-shape-facula of the TFBG diffraction light can be as large as tens of millimeters, which enables the TFBG trapping system control massive dielectric particles. We analyze the light distribution of the spatial diffraction by using the volume current method (VCM) and established a theoretical model to analyze the optical...

Optical projection tomography captures 2-D projections of rotating biological samples and computationally reconstructs 3-D structures from these projections, where hundreds of views with an angular range of π radian is desired for a reliable reconstruction. Limited-angle tomography tries to recover the structures of the sample using fewer angles of projections. However, the result is far from satisfactory due to the missing of wedge information. Here we introduce a novel view prediction technique, which is able...

supplementary statement