5 Works

Data from: Evidence accumulation and choice maintenance are dissociated in human perceptual decision making

Mads Lund Pedersen, Tor Endestad & Guido Biele
Perceptual decision making in monkeys relies on decision neurons, which accumulate evidence and maintain choices until a response is given. In humans, several brain regions have been proposed to accumulate evidence, but it is unknown if these regions also maintain choices. To test if accumulator regions in humans also maintain decisions we compared delayed and self-paced responses during a face/house discrimination decision making task. Computational modeling and fMRI results revealed dissociated processes of evidence accumulation...

Data from: Serum-free and xenobiotic-free preservation of cultured human limbal epithelial cells

Oeygunn A. Utheim, Rakibul Islam, Torstein Lyberg, Borghild Roald, Jon Roger Eidet, Maria Fideliz De La Paz, Darlene A. Dartt, Sten Raeder, Tor Paaske Utheim & Oeygunn Utheim
Aim/Purpose of the Study: To develop a one-week storage method, without serum and xenobiotics, that would maintain cell viability, morphology, and phenotype of cultured human limbal epithelial sheets. Materials and Methods: Human limbal explants were cultured on intact human amniotic membranes for two weeks. The sheets were stored in a hermetically sealed container at 23°C in either a serum-free medium with selected animal serum-derived compounds (Quantum 286) or a xenobiotic-free medium (Minimal Essential Medium) for...

Data from: Canine mammary tumours are affected by frequent copy number aberrations, including amplification of MYC and loss of PTEN

Kaja S. Borge, Silje Nord, Peter Van Loo, Ole C. Lingjærde, Gjermund Gunnes, Grethe I. G. Alnæs, Hiroko K. Solvang, Torben Lüders, Vessela N. Kristensen, Anne-Lise Børresen-Dale & Frode Lingaas
Background: Copy number aberrations frequently occur during the development of many cancers. Such events affect dosage of involved genes and may cause further genomic instability and progression of cancer. In this survey, canine SNP microarrays were used to study 117 canine mammary tumours from 69 dogs. Results: We found a high occurrence of copy number aberrations in canine mammary tumours, losses being more frequent than gains. Increased frequency of aberrations and loss of heterozygosity were...

Data from: Apolipoprotein (ApoE) polymorphism is related to differences in potential fertility in women: a case of antagonistic pleiotropy?

Grazyna Jasienska, Peter T. Ellison, Andrzej Galbarczyk, Michal Jasienski, Malgorzata Kalemba-Drozdz, Maria Kapiszewska, Ilona Nenko, Inger Thune & Anna Ziomkiewicz
The alleles that are detrimental to health, especially in older age, are thought to persist in populations because they also confer some benefits for individuals (through antagonistic pleiotropy). The ApoE4 allele at the ApoE locus, encoding apolipoprotein E (ApoE), significantly increases risk of poor health, and yet it is present in many populations at relatively high frequencies. Why has it not been replaced by natural selection with the health-beneficial ApoE3 allele? ApoE is a major...

Data from: Persistent low toxoplasma IgG avidity is common in pregnancy: experience from antenatal testing in Norway

Gry Findal, Babill Stray-Pedersen, Ellen K. Holter, Tone Berge & Pål A. Jenum
The parasite Toxoplasma gondii might harm the fetus if a woman is infected during pregnancy. IgG seroconversion and significant increase in IgG antibody amount in pregnancy indicates maternal infection. Presence of toxoplasma immunoglobulin M (IgM), immunoglobulin G (IgG) and low IgG avidity in a single serum sample indicates possible maternal infection, but positive toxoplasma IgM and low IgG avidity may persist for months and even years. We aimed to evaluate avidity development during pregnancy in...

Registration Year

  • 2015

Resource Types

  • Dataset


  • Oslo University Hospital
  • University of Oslo
  • National-Louis University
  • Polish Academy of Sciences
  • University of Barcelona
  • Wellcome Trust
  • Akershus University Hospital
  • Jagiellonian University
  • Andrzej Frycz Modrzewski Krakow University
  • Harvard University