15 Works

Supplemental Material - Elderly Outcomes After Hospitalization: The Hospital Frailty Risk Score Applied on the French Health Data Hub

Sophie Dubnitskiy-Robin, Emeline Laurent, Julien Herbert, Bertrand Fougère & Leslie Guillon-Grammatico
Supplemental Material for Elderly Outcomes After Hospitalization: The Hospital Frailty Risk Score Applied on the French Health Data Hub by Sophie Dubnitskiy-Robin, Emeline Laurent, Julien Herbert, Bertrand Fougère and Leslie Guillon-Grammatico in Journal of Aging and Health

Oral misoprostol tablets (25 µg) for induction of labor: A targeted literature review and cost analysis

Anne-Claire Poinas, Katherine Padgett, Roel de Heus, Franck Perrotin & Roland Devlieger
Various methods exist for the induction of labor (IOL), and there is limited consensus as to optimal methods. Off-label misoprostol is recommended by the World Health Organization (WHO) for IOL but preparing it into doses suitable for IOL lacks precision, with potential adverse outcomes if dosing is inaccurate. This study explores potential outcomes and costs associated with increased uptake of a low-dose (25 µg) oral misoprostol formulation1 approved for IOL, in France, Belgium and the...

Overall survival in patients with re-excision of positive microscopic margins of limb and trunk wall soft tissue sarcoma operated outside of a reference center: a nationwide cohort analysis

Francois Gouin, Eberhard Stoeckle, Charles Honoré, Mickael Ropars, Mehrdad Jafari, Jean Camille Mattei, Alexandre Rochwerger, Sébastien Carrere, Denis Waast, Gwenaël Ferron, Jean-Christophe Machiavello, Philippe Anract, Frédéric Marchal, François Sirveaux, Oren Marco, Jérôme Guiramand, Brice Paquette, Antonio Di Marco, Sylvain Causeret, Jean-Marc Guilloit, Pauline Soibinet, Dimitri Tzanis, Pierre Gimbergues, Fabrice Fiorenza, Franck Dujardin … & Jean-Yves Blay
Abstract Background This French nationwide NETSARC exhaustive prospective cohort aims to explore the impact of systematic re-excision (RE) as adjuvant care on overall survival (OS), local recurrence free survival (LRFS), and local and distant control (RFS) in patients with soft tissue sarcoma (STS) with positive microscopic margins (R1) after initial resection performed outside of a reference center. Methods Eligible patients had experienced STS surgery outside a reference center from 2010 to 2017, and had R1...

Overall survival in patients with re-excision of positive microscopic margins of limb and trunk wall soft tissue sarcoma operated outside of a reference center: a nationwide cohort analysis

Francois Gouin, Eberhard Stoeckle, Charles Honoré, Mickael Ropars, Mehrdad Jafari, Jean Camille Mattei, Alexandre Rochwerger, Sébastien Carrere, Denis Waast, Gwenaël Ferron, Jean-Christophe Machiavello, Philippe Anract, Frédéric Marchal, François Sirveaux, Oren Marco, Jérôme Guiramand, Brice Paquette, Antonio Di Marco, Sylvain Causeret, Jean-Marc Guilloit, Pauline Soibinet, Dimitri Tzanis, Pierre Gimbergues, Fabrice Fiorenza, Franck Dujardin … & Jean-Yves Blay
Abstract Background This French nationwide NETSARC exhaustive prospective cohort aims to explore the impact of systematic re-excision (RE) as adjuvant care on overall survival (OS), local recurrence free survival (LRFS), and local and distant control (RFS) in patients with soft tissue sarcoma (STS) with positive microscopic margins (R1) after initial resection performed outside of a reference center. Methods Eligible patients had experienced STS surgery outside a reference center from 2010 to 2017, and had R1...

Additional file 1 of Overall survival in patients with re-excision of positive microscopic margins of limb and trunk wall soft tissue sarcoma operated outside of a reference center: a nationwide cohort analysis

Francois Gouin, Eberhard Stoeckle, Charles Honoré, Mickael Ropars, Mehrdad Jafari, Jean Camille Mattei, Alexandre Rochwerger, Sébastien Carrere, Denis Waast, Gwenaël Ferron, Jean-Christophe Machiavello, Philippe Anract, Frédéric Marchal, François Sirveaux, Oren Marco, Jérôme Guiramand, Brice Paquette, Antonio Di Marco, Sylvain Causeret, Jean-Marc Guilloit, Pauline Soibinet, Dimitri Tzanis, Pierre Gimbergues, Fabrice Fiorenza, Franck Dujardin … & Jean-Yves Blay
Additional file 1: Supplementary material S1, S2, S3 and S4

Outcomes of mild-to-moderate postresuscitation shock after non-shockable cardiac arrest and association with temperature management: a post hoc analysis of HYPERION trial data

Ines Ziriat, Aurélie Le Thuaut, Gwenhael Colin, Hamid Merdji, Guillaume Grillet, Patrick Girardie, Bertrand Souweine, Pierre-François Dequin, Thierry Boulain, Jean-Pierre Frat, Pierre Asfar, Bruno Francois, Mickael Landais, Gaëtan Plantefeve, Jean-Pierre Quenot, Jean-Charles Chakarian, Michel Sirodot, Stéphane Legriel, Nicolas Massart, Didier Thevenin, Arnaud Desachy, Arnaud Delahaye, Vlad Botoc, Sylvie Vimeux, Frederic Martino … & Jean Baptiste Lascarrou
Abstract Background Outcomes of postresuscitation shock after cardiac arrest can be affected by targeted temperature management (TTM). A post hoc analysis of the “TTM1 trial” suggested higher mortality with hypothermia at 33 °C. We performed a post hoc analysis of HYPERION trial data to assess potential associations linking postresuscitation shock after non-shockable cardiac arrest to hypothermia at 33 °C on favourable functional outcome. Methods We divided the patients into groups with vs. without postresuscitation (defined...

Elderly Outcomes After Hospitalization: The Hospital Frailty Risk Score Applied on the French Health Data Hub

Sophie Dubnitskiy-Robin, Emeline Laurent, Julien Herbert, Bertrand Fougère & Leslie Guillon-Grammatico
Objectives: To demonstrate the association between the Hospital Frailty Risk Score (HFRS) and 30-day mortality, 30-day hospital readmission and length of stay (LOS) in France. Methods: Logistic regressions were performed using data recorded in the French national health data system (SNDS) for elderly patients (≥75 years old) hospitalized in France in 2017. Results: Over the 1,111,090 patients included, 30-day mortality was associated with the HFRS: adjusted OR (aOR) for an intermediate HFRS (5–15 points) was...

Oral misoprostol tablets (25 µg) for induction of labor: a targeted literature review and cost analysis

Anne-Claire Poinas, Katherine Padgett, Roel de Heus, Franck Perrotin & Roland Devlieger
Various methods exist for the induction of labor (IOL), and there is limited consensus as to optimal methods. Off-label misoprostol is recommended by the World Health Organization (WHO) for IOL but preparing it into doses suitable for IOL lacks precision, with potential adverse outcomes if dosing is inaccurate. This study explores potential outcomes and costs associated with increased uptake of a low-dose (25 µg) oral misoprostol formulation (Angusta; Norgine BV, Amsterdam) approved for IOL, in...

Oral misoprostol tablets (25 µg) for induction of labor: a targeted literature review and cost analysis

Anne-Claire Poinas, Katherine Padgett, Roel de Heus, Franck Perrotin & Roland Devlieger
Various methods exist for the induction of labor (IOL), and there is limited consensus as to optimal methods. Off-label misoprostol is recommended by the World Health Organization (WHO) for IOL but preparing it into doses suitable for IOL lacks precision, with potential adverse outcomes if dosing is inaccurate. This study explores potential outcomes and costs associated with increased uptake of a low-dose (25 µg) oral misoprostol formulation (Angusta; Norgine BV, Amsterdam) approved for IOL, in...

Additional file 1 of Overall survival in patients with re-excision of positive microscopic margins of limb and trunk wall soft tissue sarcoma operated outside of a reference center: a nationwide cohort analysis

Francois Gouin, Eberhard Stoeckle, Charles Honoré, Mickael Ropars, Mehrdad Jafari, Jean Camille Mattei, Alexandre Rochwerger, Sébastien Carrere, Denis Waast, Gwenaël Ferron, Jean-Christophe Machiavello, Philippe Anract, Frédéric Marchal, François Sirveaux, Oren Marco, Jérôme Guiramand, Brice Paquette, Antonio Di Marco, Sylvain Causeret, Jean-Marc Guilloit, Pauline Soibinet, Dimitri Tzanis, Pierre Gimbergues, Fabrice Fiorenza, Franck Dujardin … & Jean-Yves Blay
Additional file 1: Supplementary material S1, S2, S3 and S4

Additional file 1 of Outcomes of mild-to-moderate postresuscitation shock after non-shockable cardiac arrest and association with temperature management: a post hoc analysis of HYPERION trial data

Ines Ziriat, Aurélie Le Thuaut, Gwenhael Colin, Hamid Merdji, Guillaume Grillet, Patrick Girardie, Bertrand Souweine, Pierre-François Dequin, Thierry Boulain, Jean-Pierre Frat, Pierre Asfar, Bruno Francois, Mickael Landais, Gaëtan Plantefeve, Jean-Pierre Quenot, Jean-Charles Chakarian, Michel Sirodot, Stéphane Legriel, Nicolas Massart, Didier Thevenin, Arnaud Desachy, Arnaud Delahaye, Vlad Botoc, Sylvie Vimeux, Frederic Martino … & Jean Baptiste Lascarrou
Additional file 1: Fig. S1. Study flowchart. Table S1. Baseline characteristics and mortality in the groups with vs. without mild-to-moderate postresuscitation shock (PRS) at intensive-care-unit (ICU) admission. Table S2. Multivariate logistic regression modelling to identify admission variables associated with a favourable outcome on day 90 in the overall population (n = 532).

Additional file 1 of Outcomes of mild-to-moderate postresuscitation shock after non-shockable cardiac arrest and association with temperature management: a post hoc analysis of HYPERION trial data

Ines Ziriat, Aurélie Le Thuaut, Gwenhael Colin, Hamid Merdji, Guillaume Grillet, Patrick Girardie, Bertrand Souweine, Pierre-François Dequin, Thierry Boulain, Jean-Pierre Frat, Pierre Asfar, Bruno Francois, Mickael Landais, Gaëtan Plantefeve, Jean-Pierre Quenot, Jean-Charles Chakarian, Michel Sirodot, Stéphane Legriel, Nicolas Massart, Didier Thevenin, Arnaud Desachy, Arnaud Delahaye, Vlad Botoc, Sylvie Vimeux, Frederic Martino … & Jean Baptiste Lascarrou
Additional file 1: Fig. S1. Study flowchart. Table S1. Baseline characteristics and mortality in the groups with vs. without mild-to-moderate postresuscitation shock (PRS) at intensive-care-unit (ICU) admission. Table S2. Multivariate logistic regression modelling to identify admission variables associated with a favourable outcome on day 90 in the overall population (n = 532).

Outcomes of mild-to-moderate postresuscitation shock after non-shockable cardiac arrest and association with temperature management: a post hoc analysis of HYPERION trial data

Ines Ziriat, Aurélie Le Thuaut, Gwenhael Colin, Hamid Merdji, Guillaume Grillet, Patrick Girardie, Bertrand Souweine, Pierre-François Dequin, Thierry Boulain, Jean-Pierre Frat, Pierre Asfar, Bruno Francois, Mickael Landais, Gaëtan Plantefeve, Jean-Pierre Quenot, Jean-Charles Chakarian, Michel Sirodot, Stéphane Legriel, Nicolas Massart, Didier Thevenin, Arnaud Desachy, Arnaud Delahaye, Vlad Botoc, Sylvie Vimeux, Frederic Martino … & Jean Baptiste Lascarrou
Abstract Background Outcomes of postresuscitation shock after cardiac arrest can be affected by targeted temperature management (TTM). A post hoc analysis of the “TTM1 trial” suggested higher mortality with hypothermia at 33 °C. We performed a post hoc analysis of HYPERION trial data to assess potential associations linking postresuscitation shock after non-shockable cardiac arrest to hypothermia at 33 °C on favourable functional outcome. Methods We divided the patients into groups with vs. without postresuscitation (defined...

Supplemental Material - Elderly Outcomes After Hospitalization: The Hospital Frailty Risk Score Applied on the French Health Data Hub

Sophie Dubnitskiy-Robin, Emeline Laurent, Julien Herbert, Bertrand Fougère & Leslie Guillon-Grammatico
Supplemental Material for Elderly Outcomes After Hospitalization: The Hospital Frailty Risk Score Applied on the French Health Data Hub by Sophie Dubnitskiy-Robin, Emeline Laurent, Julien Herbert, Bertrand Fougère and Leslie Guillon-Grammatico in Journal of Aging and Health

Elderly Outcomes After Hospitalization: The Hospital Frailty Risk Score Applied on the French Health Data Hub

Sophie Dubnitskiy-Robin, Emeline Laurent, Julien Herbert, Bertrand Fougère & Leslie Guillon-Grammatico
Objectives: To demonstrate the association between the Hospital Frailty Risk Score (HFRS) and 30-day mortality, 30-day hospital readmission and length of stay (LOS) in France. Methods: Logistic regressions were performed using data recorded in the French national health data system (SNDS) for elderly patients (≥75 years old) hospitalized in France in 2017. Results: Over the 1,111,090 patients included, 30-day mortality was associated with the HFRS: adjusted OR (aOR) for an intermediate HFRS (5–15 points) was...

Registration Year

  • 2022
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Affiliations

  • Centre Hospitalier Universitaire de Tours
    15
  • François Rabelais University
    10
  • Hôpital Cochin
    8
  • Centre Hospitalier Universitaire de Limoges
    8
  • Hôpitaux Universitaires de Strasbourg
    8
  • Centre Hospitalier Universitaire de Nantes
    6
  • University of Strasbourg
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  • Centre for Research in Epidemiology and Population Health
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  • Centre Hospitalier Universitaire d'Angers
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  • Centre Hospitalier Universitaire de Poitiers
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