13 Works

Data from: Comparative and population mitogenomic analyses of Madagascar’s extinct, giant ‘subfossil’ lemurs

Logan Kistler, Aakrosh Ratan, Laurie R. Godfrey, Brooke E. Crowley, Cris E. Hughes, Runhua Lei, Yinqui Cui, Mindy L. Wood, Kathleen M. Muldoon, Haingoson Andriamialison, John J. McGraw, Lynn P. Tomsho, Stephan C. Schuster, Webb Miller, Edward E. Louis, Anne D. Yoder, Ripan S. Malhi, George H. Perry & Yinqiu Cui
Humans first arrived on Madagascar only a few thousand years ago. Subsequent habitat destruction and hunting activities have had significant impacts on the island's biodiversity, including the extinction of megafauna. For example, we know of 17 recently extinct ‘subfossil’ lemur species, all of which were substantially larger (body mass ∼11–160 kg) than any living population of the ∼100 extant lemur species (largest body mass ∼6.8 kg). We used ancient DNA and genomic methods to study...

Data from: Exploring the potential pharmacodynamic material basis and pharmacologic mechanism of the Fufang-Xialian-Capsule in chronic atrophic gastritis by network pharmacology approach based on the components absorbed into the blood

Shizhe Li, Tengfei Xu, Shu Liu, Zhiqiang Liu, Zifeng Pi, Fengrui Song & Yongri Jin
In this study, a new network pharmacology approach based on the components absorbed into the blood was utilized to investigate the pharmacodynamic material basis and the pharmacologic mechanism of the Fufang-Xialian-Capsule (FXL) in treating chronic atrophic gastritis (CAG). Initially, we confirmed the components absorbed into the blood by ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. Then, the network approach, which was based on the results of components absorbed into the blood, was utilized...

Data from: A new small captorhinid reptile from the lower Permian of Oklahoma and resource partitioning among small captorhinids in the Richards Spur fauna

Sean P. Modesto, Diane Scott & Robert R. Reisz
Two partial reptile skulls and six dentigerous fragments from the lower Permian Richards Spur locality of Oklahoma represent a new genus and species of small captorhinid reptile. Labidosauriscus richardi gen. et sp. nov. is distinguished from other captorhinids in the reduction of the height of the ridges forming the characteristic net-like, ridge-and-pit cranial sculpturing of captorhinids, and the superimposition of a system of finer pits and furrows over the primary ridge-and-pit cranial ornamentation. Labidosauriscus richardi...

Prevalence and correlates of overweight and obesity among adolescents in northeastern China: a cross-sectional study

Ruixin Duan, Changgui Kou, Jing Jie, Wei Bai, Xiaoxin Lan, Yuanyuan Li, Xiao Yu, Bo Zhu & Haibo Yuan
Abstract Objectives: To estimate the prevalence of overweight/obesity among adolescents and to evaluate the associated factors in this group in Changchun City, northeastern China. Methods: A cross-sectional study of 1955 adolescents aged 11–18 years was conducted in Changchun City, using stratified cluster sampling. Parents and caregivers of children completed the questionnaires as requested without objection; the questionnaire included demographic characteristics and anthropometric parameters. Univariate and multivariate logistic regression analyses were performed to analyze the relationship...

Nonlinear dynamic model and rollover threshold of a liquid tank semi-trailer

Miao Yu, Shiwu Li, Wencai Sun & Xue Wen
A refined dynamic model of a tractor-semitrailer, including the nonlinear tire force and tank swing force, is established, and the fluid force and torque in the liquid tank are obtained through simulation by using the fluid mechanics software Fluent. Two kinds of tests, the tire corner stiffness test and tire roll stiffness test, are designed and performed using the KHAT flat bed test rig for tires, and a nonlinear model of the tire is obtained....

Analysis of potential earthquake precursory pattern from Mw>=7.0 earthquakes in Mexico

Xitong Xu
In this work, we study seismic precursors from air temperature data of the National Center for Environmental Prediction (NCEP), Global Navigation Satellite System (GNSS) based Total Electron Content (TEC) and electron density retrieved from Swarm satellite (Alpha) data in Mw>=7.0 earthquakes in Mexico. The spatial-temporal evolution of seismic thermal anomalies is explored through NCEP, and synergistic observations of Swarm satellite and GNSS station are capable of providing more comprehensive information about disturbances in ionosphere. Our...

Data from: 5′-(CGA)n sequence-assisted pH-controlled assembly of supramolecular DNA nanostructure

Yuting Yan, Yanwei Cao, Chunsheng Xiao, Yang Li, Xiaoxuan Xiang & Xinhua Guo
Herein, the DNA strands containing 5'-(CGA)n and consecutive guanines are used to construct supramolecular DNA nanostructures that are size-controlled by pH values. Additionally, the introduction of thymine linkers within DNA nanostructures is necessary to maintain the stability of long sized nanostructures. This work also demonstrates a method for accurately building DNA nanostructures.

Late Cretaceous-Tertiary tectonic inversion of northeastern Asian continental margin: insight from the low temperature thermochronology in NE China

Jianping Zhou , Dunkl Dunkl Istvan , Yongjiang Liu , Weimin Li & Hilmar von Eynatten
University of Göttingen, Geoscience Center, Department of Sedimentology and Environmental Geology,Göttingen, Germany (1); Key Lab of Submarine Geoscience and Prospecting Techniques, MOE, Institute for Advanced Ocean Study, College of Marine Geosciences, Ocean University of China, Qingdao, China (2); Laboratory for Marine Mineral Resources, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China (3); College of Earth Sciences, Jilin University, Jianshe Str. 2199, Changchun 130061, Jilin, China (4)

The Cretaceous Songliao basin in Northeast...

Soil dissolved organic carbon in terrestrial ecosystems: global budget, spatial distribution and controls

Xiaofeng Xu, Ziyu Guo, Yihui Wang & Zhongmei Wan
Aims: Soil dissolved organic carbon (DOC) is a primary form of labile carbon in terrestrial ecosystems and therefore plays a vital role in soil carbon cycling. This study aims to quantify the budgets of soil DOC at biome- and global levels and to examine the variations in soil DOC and their environmental controls. Location: Global Time period: 1981 - 2019 Method: We compiled a global dataset and analyzed the concentration and distribution of DOC across...

Data from: Polycaprolactone nanofibers loaded with 20(S)-Protopanaxadiol for in vitro and vivo antitumor activity study

Danqing Liu, Zhiqiang Cheng, Qingjie Feng, Hejie Li, Shufeng Ye, Bo Teng, Qing-Jie Feng, He-Jie Li, Dan-Qing Liu & Shu-Feng Ye
In this work, 20(S)-Protopanaxadiol (PPD) loaded polycaprolactone (PCL) nanofibers were successfully fabricated by electrospinning technique using tween-80 as a solubilizer. Firstly, smooth and continuous nanofibers were collected by using suitable solvent and appropriate spinning conditions. Secondly, nanofiber mats were characterized by scanning electron microscope (SEM), thermogravimetric (TG) analysis, Fourier transform infrared spectroscopy (FTIR) and mechanical test. Finally, nanofibrous membranes were evaluated using water contact angle, in vitro drug release, biodegradation test, in vitro and vivo...

Data from: The early history of Annonaceae (Magnoliales) in Southeast Asia suggests floristic exchange between India and Pan-Indochina by the late Oligocene

Qijia Li, Gongle Shi, Yusheng Liu, Qiongyao Fu, Jianhua Jin & Cheng Quan
The collision between India and Eurasia in the mid‐Palaeogene facilitated terrestrial floristic exchange. However, due to the complexity of this geological event and scarcity of fossil record, the plant migration patterns between the two plates are still highly debated. In this study, we focus on the Oligocene floristic exchange between India and Pan‐Indochina mainly based on a carpological study of Annonaceae, an emblematic family unique in its pantropical distribution and frugivore‐based dispersal strategy. A new...

Data from: Ancient DNA provides new insight into the maternal lineages and domestication of Chinese donkeys

Lu Han, Songbiao Zhu, Chao Ning, Dawei Cai, Kai Wang, Quanjia Chen, Songmei Hu, Junkai Yang, Jing Shao, Hong Zhu & Hui Zhou
Background: The donkey (Equus asinus) is an important domestic animal that provides a reliable source of protein and method of transportation for many human populations. However, the process of domestication and the dispersal routes of the Chinese donkey are still unclear, as donkey remains are sparse in the archaeological record and often confused with horse remains. To explore the maternal origins and dispersal route of Chinese donkeys, both mitochondrial DNA D-loop and cytochrome b gene...

Data from: Active site loop conformation regulates promiscuous activity in a lactonase from Geobacillus kaustophilus HTA426

Yu Zhang, Jiao An, Guang-Yu Yang, Aixi Bai, Baisong Zheng, Zhiyong Lou, Geng Wu, Wei Ye, Hai-Feng Chen, Yan Feng & Giuseppe Manco
Enzyme promiscuity is a prerequisite for fast divergent evolution of biocatalysts. A phosphotriesterase-like lactonase (PLL) from Geobacillus kaustophilus HTA426 (GkaP) exhibits main lactonase and promiscuous phosphotriesterase activities. To understand its catalytic and evolutionary mechanisms, we investigated a “hot spot” in the active site by saturation mutagenesis as well as X-ray crystallographic analyses. We found that position 99 in the active site was involved in substrate discrimination. One mutant, Y99L, exhibited 11-fold improvement over wild-type in...

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