11 Works

Data from: Neural control of balance during walking

Hendrik Reimann, Tyler Fettrow, Elizabeth D. Thompson & John J. Jeka
Neural control of standing balance has been extensively studied. However, most falls occur during walking rather than standing, and findings from standing balance research do not necessarily carry over to walking. This is primarily due to the constraints of the gait cycle: Body configuration changes dramatically over the gait cycle, necessitating different responses as this configuration changes. Notably, certain responses can only be initiated at specific points in the gait cycle, leading to onset times...

Data from: Molecular evidence for the paraphyly of Scolecophidia and its evolutionary implications

Aurélien Miralles, Julie Marin, Damien Markus, Anthony Herrel, Blair S. Hedges & Nicolas Vidal
The phylogenetic relationships between the three main clades of worm snakes remain controversial. This question is, however, crucial to elucidate the origin of the successful snake radiation, as these burrowing and miniaturized wormlike organisms represent the earliest branching clades among the snake tree. The present molecular phylogenetic study, intended to minimize the amount of missing data, provides fully resolved inter-subfamilial relationships among Typhlopidae. It also brings robust evidence that worm snakes (Scolecophidia) are paraphyletic, with...

Data from: Shifts to earlier selfing in sympatry may reduce costs of pollinator sharing

April M. Randle, Rachel B. Spigler & Susan Kalisz
Coexisting plant congeners often experience strong competition for resources. Competition for pollinators can result in direct fitness costs via reduced seed set or indirect costs via heterospecific pollen transfer (HPT), causing subsequent gamete loss and unfit hybrid offspring production. Autonomous selfing may alleviate these costs, but to preempt HPT, selfing should occur early, before opportunities for HPT occur (i.e. “preemptive selfing hypothesis”). We evaluated conditions for this hypothesis in Collinsia sister species, C. linearis and...

Data from: Gene expression profiling reveals deep-sea coral response to the Deepwater Horizon oil spill

Danielle M. DeLeo, Santiago Herrera, Stephen D. Lengyel, Andrea M. Quattrini, Rob J. Kulathinal & Erik E. Cordes
Deep-sea coral communities are key components of the Gulf of Mexico ecosystem and were adversely affected by the Deepwater Horizon (DWH) oil spill. Coral colonies exposed to oil and dispersant exhibited mortality, damage, and physiological signatures of stress. Understanding how corals respond to oil and dispersant exposure at the molecular level is important to elucidate the sub-lethal effects of the DWH disaster, and reveal broader patterns of coral stress responses. Gene expression profiles from RNAseq...

Functional convergence of gliP and aspf1 in Aspergillus fumigatus pathogenicity

Hong Liu, Wenjie Xu, Norma V. Solis, Carol Woolford, Aaron P. Mitchell & Scott G. Filler
Gliotoxin contributes to the virulence of the fungus Aspergillus fumigatus in non-neutropenic mice that are immunosuppressed with corticosteroids. To investigate how the absence of gliotoxin affects both the fungus and the host, we used a nanoString nCounter to analyze their transcriptional responses during pulmonary infection of a non-neutropenic host with a gliotoxin-deficient ΔgliP mutant. We found that the ΔgliP mutation led to increased expression of aspf1, which specifies a secreted ribotoxin. Prior studies have shown...

Data from: Universal target-enrichment baits for anthozoan (Cnidaria) phylogenomics: new approaches to long-standing problems

Andrea M. Quattrini, Brant C. Faircloth, Luisa F. Dueñas, Thomas C.L. Bridge, Mercer R. Brügler, Ivan F. Calixto-Botía, Danielle M. DeLeo, Sylvain Foret, Santiago Herrera, Simon M.Y. Lee, David J. Miller, Carlos Prada, Gandhi Rádis-Baptista, Catalina Ramírez-Portilla, Juan A. Sánchez, Estefania Rodriguez, Catherine S. McFadden, Tom C. L. Bridge & Simon M. Y. Lee
Anthozoans (e.g., corals, anemones) are an ecologically important and diverse group of marine metazoans that occur from shallow to deep waters worldwide. However, our understanding of the evolutionary relationships among the ~7500 species within this class is hindered by the lack of phylogenetically informative markers that can be reliably sequenced across a diversity of taxa. We designed and tested 16,308 RNA baits to capture 720 Ultraconserved Element loci and 1,071 exon loci. Library preparation and...

Conducting a NIBS Experiment: Hardware

Lindsey Tepfer, Shaoming Wang, Jane Gaisinsky, Tommy Ng & David Smith

Data from: A multispecies coalescent model for quantitative traits

Fabio K. Mendes, Jesualdo A. Fuentes-González, Joshua G. Schraiber & Matthew W. Hahn
We present a multispecies coalescent model for quantitative traits that allows for evolutionary inferences at micro- and macroevolutionary scales. A major advantage of this model is its ability to incorporate genealogical discordance underlying a quantitative trait. We show that discordance causes a decrease in the expected trait covariance between more closely related species relative to more distantly related species. If unaccounted for, this outcome can lead to an overestimation of a trait's evolutionary rate, to...

Functional convergence of gliP and aspf1 in Aspergillus fumigatus pathogenicity

Hong Liu, Wenjie Xu, Norma V. Solis, Carol Woolford, Aaron P. Mitchell & Scott G. Filler
Gliotoxin contributes to the virulence of the fungus Aspergillus fumigatus in non-neutropenic mice that are immunosuppressed with corticosteroids. To investigate how the absence of gliotoxin affects both the fungus and the host, we used a nanoString nCounter to analyze their transcriptional responses during pulmonary infection of a non-neutropenic host with a gliotoxin-deficient ΔgliP mutant. We found that the ΔgliP mutation led to increased expression of aspf1, which specifies a secreted ribotoxin. Prior studies have shown...

Data from: Selection analyses of paired HIV-1 gag and gp41 sequences obtained before and after antiretroviral therapy

Philip Lei Tzou, Soo-Yon Rhee, Sergei L. Kosakovsky Pond, Justen Manasa & Robert W. Shafer
Most HIV-1-infected individuals with virological failure (VF) on a pharmacologically-boosted protease inhibitor (PI)-containing regimen do not develop PI-resistance protease mutations. One proposed explanation is that mutations in HIV-1 gag or gp41 cytoplasmic domain might also reduce PI susceptibility. In a recent study of paired gag and gp41 sequences from individuals with VF on a PI-containing regimen, we did not identify PI-selected mutations and concluded that if such mutations existed, larger numbers of paired sequences from...

2018 MLA-PHIL Chapter CE Course: Easy Steps to Building A Team-Based Systematic Review Service

Stephanie Roth
MLA CE 2 credit course materials provided.

Registration Year

  • 2018
    11

Resource Types

  • Dataset
    9
  • Text
    2

Affiliations

  • Temple University
    11
  • Florida International University
    4
  • Affiliated Hospital of Nantong University
    2
  • Huazhong University of Science and Technology
    2
  • Tokyo University of Agriculture and Technology
    2
  • Beihang University
    2
  • Lehigh University
    2
  • Ministry of Education of the People's Republic of China
    2
  • Shandong University
    2
  • Huazhong Agricultural University
    2