202 Works

Additional file 1 of Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium

Pål Møller, Toni Seppälä, James G. Dowty, Saskia Haupt, Mev Dominguez-Valentin, Lone Sunde, Inge Bernstein, Christoph Engel, Stefan Aretz, Maartje Nielsen, Gabriel Capella, Dafydd Gareth Evans, John Burn, Elke Holinski-Feder, Lucio Bertario, Bernardo Bonanni, Annika Lindblom, Zohar Levi, Finlay Macrae, Ingrid Winship, John-Paul Plazzer, Rolf Sijmons, Luigi Laghi, Adriana Della Valle, Karl Heinimann … & Mark A. Jenkins
Additional file 1.

sj-pdf-1-jcb-10.1177_0271678X221126830 - Supplemental material for Quantification of the purinergic P2X7 receptor with [11C]SMW139 improves through correction for brain-penetrating radiometabolites

Joachim Brumberg, Richard Aarnio, Anton Forsberg, Päivi Marjamäki, Vera Kerstens, Mohammad M Moein, Sangram Nag, Saara Wahlroos, Michael Kassiou, Albert D Windhorst, Christer Halldin, Merja Haaparanta-Solin, Patrik Fazio, Vesa Oikonen, Juha O Rinne & Andrea Varrone
Supplemental material, sj-pdf-1-jcb-10.1177_0271678X221126830 for Quantification of the purinergic P2X7 receptor with [11C]SMW139 improves through correction for brain-penetrating radiometabolites by Joachim Brumberg, Richard Aarnio, Anton Forsberg, Päivi Marjamäki, Vera Kerstens, Mohammad M Moein, Sangram Nag, Saara Wahlroos, Michael Kassiou, Albert D Windhorst, Christer Halldin, Merja Haaparanta-Solin, Patrik Fazio, Vesa Oikonen, Juha O Rinne and Andrea Varrone in Journal of Cerebral Blood Flow & Metabolism

Quantification of the purinergic P2X7 receptor with [11C]SMW139 improves through correction for brain-penetrating radiometabolites

Joachim Brumberg, Richard Aarnio, Anton Forsberg, Päivi Marjamäki, Vera Kerstens, Mohammad M Moein, Sangram Nag, Saara Wahlroos, Michael Kassiou, Albert D Windhorst, Christer Halldin, Merja Haaparanta-Solin, Patrik Fazio, Vesa Oikonen, Juha O Rinne & Andrea Varrone
The membrane-based purinergic 7 receptor (P2X7R) is expressed on activated microglia and the target of the radioligand [11C]SMW139 for in vivo assessment of neuroinflammation. This study investigated the contribution of radiolabelled metabolites which potentially affect its quantification. Ex vivo high-performance liquid chromatography with a radio detector (radioHPLC) was used to evaluate the parent and radiometabolite fractions of [11C]SMW139 in the brain and plasma of eleven mice. Twelve healthy humans underwent 90-min [11C]SMW139 brain PET with...

Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data

Sean M. Hughes, Claire N. Levy, Ronit Katz, Erica M. Lokken, Melis N. Anahtar, Melissa Barousse Hall, Frideborg Bradley, Philip E. Castle, Valerie Cortez, Gustavo F. Doncel, Raina Fichorova, Paul L. Fidel, Keith R. Fowke, Suzanna C. Francis, Mimi Ghosh, Loris Y. Hwang, Mariel Jais, Vicky Jespers, Vineet Joag, Rupert Kaul, Jordan Kyongo, Timothy Lahey, Huiying Li, Julia Makinde, Lyle R. McKinnon … & Florian Hladik
Abstract Background Hormonal changes during the menstrual cycle play a key role in shaping immunity in the cervicovaginal tract. Cervicovaginal fluid contains cytokines, chemokines, immunoglobulins, and other immune mediators. Many studies have shown that the concentrations of these immune mediators change throughout the menstrual cycle, but the studies have often shown inconsistent results. Our understanding of immunological correlates of the menstrual cycle remains limited and could be improved by meta-analysis of the available evidence. Methods...

Additional file 2 of Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data

Sean M. Hughes, Claire N. Levy, Ronit Katz, Erica M. Lokken, Melis N. Anahtar, Melissa Barousse Hall, Frideborg Bradley, Philip E. Castle, Valerie Cortez, Gustavo F. Doncel, Raina Fichorova, Paul L. Fidel, Keith R. Fowke, Suzanna C. Francis, Mimi Ghosh, Loris Y. Hwang, Mariel Jais, Vicky Jespers, Vineet Joag, Rupert Kaul, Jordan Kyongo, Timothy Lahey, Huiying Li, Julia Makinde, Lyle R. McKinnon … & Florian Hladik
Additional file 2. Amendments to the pre-registered protocol.

Additional file 1 of Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data

Sean M. Hughes, Claire N. Levy, Ronit Katz, Erica M. Lokken, Melis N. Anahtar, Melissa Barousse Hall, Frideborg Bradley, Philip E. Castle, Valerie Cortez, Gustavo F. Doncel, Raina Fichorova, Paul L. Fidel, Keith R. Fowke, Suzanna C. Francis, Mimi Ghosh, Loris Y. Hwang, Mariel Jais, Vicky Jespers, Vineet Joag, Rupert Kaul, Jordan Kyongo, Timothy Lahey, Huiying Li, Julia Makinde, Lyle R. McKinnon … & Florian Hladik
Additional file 1. Supporting methods documents. PRISMA-P and PRISMA-IPD checklists, database search strategies, manuscript screening form, risk of bias instrument, and strength of evidence tool.

Additional file 4 of Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data

Sean M. Hughes, Claire N. Levy, Ronit Katz, Erica M. Lokken, Melis N. Anahtar, Melissa Barousse Hall, Frideborg Bradley, Philip E. Castle, Valerie Cortez, Gustavo F. Doncel, Raina Fichorova, Paul L. Fidel, Keith R. Fowke, Suzanna C. Francis, Mimi Ghosh, Loris Y. Hwang, Mariel Jais, Vicky Jespers, Vineet Joag, Rupert Kaul, Jordan Kyongo, Timothy Lahey, Huiying Li, Julia Makinde, Lyle R. McKinnon … & Florian Hladik
Additional file 4. Concentration and forest plots for each individual immune mediator. Concentration plots - Each symbol shows the concentration of the indicated immune mediator in a single sample. Each study is plotted separately. Lines connect samples from the same participant; in some cases participants provided multiple samples in the same phase, in which case multiple symbols within the same phase may be connected. Pale grey symbols are below the lower limit of detection and...

Additional file 2 of Characteristics and outcome of traumatic cardiac arrest at a level 1 trauma centre over 10 years in Sweden

Daniel Ohlén, Magnus Hedberg, Paula Martinsson, Erik von Oelreich, Therese Djärv & Malin Jonsson Fagerlund
Supplementary Material 2

The WID-CIN test identifies women with, and at risk of, cervical intraepithelial neoplasia grade 3 and invasive cervical cancer

James E. Barrett, Karin Sundström, Allison Jones, Iona Evans, Jiangrong Wang, Chiara Herzog, Joakim Dillner & Martin Widschwendter
Abstract Background Cervical screening is transitioning from primary cytology to primary human papillomavirus (HPV) testing. HPV testing is highly sensitive but there is currently no high-specificity triage method for colposcopy referral to detect cervical intraepithelial neoplasia grade 3 or above (CIN3+) in women positive for high-risk (hr) HPV subtypes. An objective, automatable test that could accurately perform triage, independently of sample heterogeneity and age, is urgently required. Methods We analyzed DNA methylation at ~850,000 CpG...

Potential living kidney donors’ positive experiences of an information letter from healthcare: a descriptive qualitative study

Eva Lagging, Kjerstin Larsson, Jonas Wadström, Linda Gyllström Krekula & Annika Tibell
Abstract Background Patients who need a live donor kidney transplant (LDKT) must often ask potential donors (PLDs) themselves. This is a difficult task and healthcare could unburden them by making this first contact, ensuring also that PLDs receive correct information. We investigated how PLDs experience receiving a letter from healthcare about LDKT, live kidney donation, and inviting them to meet with professionals to get more information. Methods The letter (LD-letter) was sent to a cohort...

Additional file 2 of Potential living kidney donors’ positive experiences of an information letter from healthcare: a descriptive qualitative study

Eva Lagging, Kjerstin Larsson, Jonas Wadström, Linda Gyllström Krekula & Annika Tibell
The interview guide including survey questions.

Additional file 1 of Designing synthetic consortia of Trichoderma strains that improve antagonistic activities against pathogens and cucumber seedling growth

Dazhi Hao, Bo Lang, Yongkun Wang, Xinhua Wang, Tong Liu & Jie Chen
Additional file 1: Table S1. Trichoderma strains used in this study. Fig. S1 Detection of antagonistic characteristics and functions of different Trichoderma strains.

Additional file 3 of Designing synthetic consortia of Trichoderma strains that improve antagonistic activities against pathogens and cucumber seedling growth

Dazhi Hao, Bo Lang, Yongkun Wang, Xinhua Wang, Tong Liu & Jie Chen
Additional file 3. Collection Proof of Strain GDFS1009.

Additional file 5 of Designing synthetic consortia of Trichoderma strains that improve antagonistic activities against pathogens and cucumber seedling growth

Dazhi Hao, Bo Lang, Yongkun Wang, Xinhua Wang, Tong Liu & Jie Chen
Additional file 5. Collection Proof of Strain RW10569.

Designing synthetic consortia of Trichoderma strains that improve antagonistic activities against pathogens and cucumber seedling growth

Dazhi Hao, Bo Lang, Yongkun Wang, Xinhua Wang, Tong Liu & Jie Chen
Abstract Background Trichoderma spp. are important agricultural biocontrol microorganisms that are often used as effective components of microbial fungicides and microbial biofertilizers. However, most of these products are prepared by a single strain in monoculture, which significantly limits the biocontrol efficiency and stability of Trichoderma products. Therefore, the establishment of a design and screening approach for consortia with multi-Trichoderma strains for co-culture is of great importance to overcome the shortage of traditional Trichoderma biocontrol products....

Additional file 3 of NKD2 is correlated with the occurrence, progression and prognosis of thyroid carcinoma

Yu Gao, Yiwei Wang & Rende Guo
Additional file 3. The original results of western blot.

Additional file 1 of NKD2 is correlated with the occurrence, progression and prognosis of thyroid carcinoma

Yu Gao, Yiwei Wang & Rende Guo
Additional file 1: Table S1. Clinical features of thyroid cancer patients.

Understanding the transport networks complex between South Asia, Southeast Asia and China during the late Neolithic and Bronze Age

Minmin Ma, Yongxiu Lu, Guanghui Dong, Lele Ren, Rui Min, Lihong Kang, Zhonghua Zhu, Xiaorui Li, Bo Li, Zhijian Yang, Nongbu Cili, Ruiliang Liu, Yu Gao & Fahu Chen
The emergence and intensification of transcontinental exchange during both the Late Neolithic and Bronze Age profoundly influenced the social history of Eurasia. While scholars have intensively discussed east-west long-distance communication along the proto-Silk Road, the north-south transport networks that connected China to South and Southeast Asia during the Late Neolithic and Bronze Age have attracted much less attention in the scholarly literature based on archeological science data. In this paper, we find new radiocarbon dates...

sj-pdf-1-hol-10.1177_09596836221131698 – Supplemental material for Understanding the transport networks complex between South Asia, Southeast Asia and China during the late Neolithic and Bronze Age

Minmin Ma, Yongxiu Lu, Guanghui Dong, Lele Ren, Rui Min, Lihong Kang, Zhonghua Zhu, Xiaorui Li, Bo Li, Zhijian Yang, Nongbu Cili, Ruiliang Liu, Yu Gao & Fahu Chen
Supplemental material, sj-pdf-1-hol-10.1177_09596836221131698 for Understanding the transport networks complex between South Asia, Southeast Asia and China during the late Neolithic and Bronze Age by Minmin Ma, Yongxiu Lu, Guanghui Dong, Lele Ren, Rui Min, Lihong Kang, Zhonghua Zhu, Xiaorui Li, Bo Li, Zhijian Yang, Nongbu Cili, Ruiliang Liu, Yu Gao and Fahu Chen in The Holocene

Understanding the transport networks complex between South Asia, Southeast Asia and China during the late Neolithic and Bronze Age

Minmin Ma, Yongxiu Lu, Guanghui Dong, Lele Ren, Rui Min, Lihong Kang, Zhonghua Zhu, Xiaorui Li, Bo Li, Zhijian Yang, Nongbu Cili, Ruiliang Liu, Yu Gao & Fahu Chen
The emergence and intensification of transcontinental exchange during both the Late Neolithic and Bronze Age profoundly influenced the social history of Eurasia. While scholars have intensively discussed east-west long-distance communication along the proto-Silk Road, the north-south transport networks that connected China to South and Southeast Asia during the Late Neolithic and Bronze Age have attracted much less attention in the scholarly literature based on archeological science data. In this paper, we find new radiocarbon dates...

Plain language summary of results from the JAVELIN Bladder 100 study: avelumab maintenance treatment for advanced urothelial cancer. Spanish translation.

Petros Grivas, John A. Blake-Haskins, Nuno Costa, Bo Huang, Robert J. Laliberte, Daniel P. Petrylak, Jeanny B. Aragon-Ching, Joaquim Bellmunt, Cora N. Sternberg, Evgeny Kopyltsov, Norihiko Tsuchiya, Srikala S. Sridhar, Yohann Loriot, Anders Ullén, Wim Demey, Sinisa Radulović, Haralabos Kalofonos, Howard Gurney, Begoña P. Valderrama, Claudia Caserta, Eric Voog, Se-Hoon Park & Thomas Powles
Spanish translation of plain language summary of results from the JAVELIN Bladder 100 study

sj-docx-1-msc-10.1177_09691413221126677 - Supplemental material for Availability of data for cost-effectiveness comparison of child vision and hearing screening programmes

Jan Kik, Eveline A.M. Heijnsdijk, Allison R. Mackey, Gwen Carr, Anna M Horwood, Maria Fronius, Jill Carlton, Helen J Griffiths, Inger M Uhlén & Huibert Jan Simonsz
Supplemental material, sj-docx-1-msc-10.1177_09691413221126677 for Availability of data for cost-effectiveness comparison of child vision and hearing screening programmes by Jan Kik, Eveline A.M. Heijnsdijk, Allison R. Mackey, Gwen Carr, Anna M Horwood, Maria Fronius, Jill Carlton, Helen J Griffiths, Inger M Uhlén, Huibert Jan Simonsz and Country-Committees Joint-Partnership of the EUSCREEN Study Consortium in Journal of Medical Screening

sj-docx-2-msc-10.1177_09691413221126677 - Supplemental material for Availability of data for cost-effectiveness comparison of child vision and hearing screening programmes

Jan Kik, Eveline A.M. Heijnsdijk, Allison R. Mackey, Gwen Carr, Anna M Horwood, Maria Fronius, Jill Carlton, Helen J Griffiths, Inger M Uhlén & Huibert Jan Simonsz
Supplemental material, sj-docx-2-msc-10.1177_09691413221126677 for Availability of data for cost-effectiveness comparison of child vision and hearing screening programmes by Jan Kik, Eveline A.M. Heijnsdijk, Allison R. Mackey, Gwen Carr, Anna M Horwood, Maria Fronius, Jill Carlton, Helen J Griffiths, Inger M Uhlén, Huibert Jan Simonsz and Country-Committees Joint-Partnership of the EUSCREEN Study Consortium in Journal of Medical Screening

sj-docx-4-msc-10.1177_09691413221126677 - Supplemental material for Availability of data for cost-effectiveness comparison of child vision and hearing screening programmes

Jan Kik, Eveline A.M. Heijnsdijk, Allison R. Mackey, Gwen Carr, Anna M Horwood, Maria Fronius, Jill Carlton, Helen J Griffiths, Inger M Uhlén & Huibert Jan Simonsz
Supplemental material, sj-docx-4-msc-10.1177_09691413221126677 for Availability of data for cost-effectiveness comparison of child vision and hearing screening programmes by Jan Kik, Eveline A.M. Heijnsdijk, Allison R. Mackey, Gwen Carr, Anna M Horwood, Maria Fronius, Jill Carlton, Helen J Griffiths, Inger M Uhlén, Huibert Jan Simonsz and Country-Committees Joint-Partnership of the EUSCREEN Study Consortium in Journal of Medical Screening

German translation of the JAVELIN Bladder 100 study: avelumab maintenance treatment for advanced urothelial cancer

Petros Grivas, John A. Blake-Haskins, Nuno Costa, Bo Huang, Robert J. Laliberte, Daniel P. Petrylak, Jeanny B. Aragon-Ching, Joaquim Bellmunt, Cora N. Sternberg, Evgeny Kopyltsov, Norihiko Tsuchiya, Srikala S. Sridhar, Yohann Loriot, Anders Ullén, Wim Demey, Sinisa Radulović, Haralabos Kalofonos, Howard Gurney, Begoña P. Valderrama, Claudia Caserta, Eric Voog, Se-Hoon Park & Thomas Powles
German translation of the JAVELIN Bladder 100 study: avelumab maintenance treatment for advanced urothelial cancer

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