223 Works

Additional file 1 of Identification of risk factors for incident cervical insufficiency in nulliparous and parous women: a population-based case-control study

Lili Meng, Sara Öberg, Anna Sandström, Chen Wang & Marie Reilly
Additional file 1: Table S1. ICD codes used to define medical diagnoses and surgical procedures.

Intestinal gluconeogenesis is downregulated in pediatric patients with celiac disease

Olof Karlson, Henrik Arnell, Audur H. Gudjonsdottir, Daniel Agardh & Åsa Torinsson Naluai
Abstract Background Untreated celiac disease (CD) patients have increased levels of blood glutamine and a lower duodenal expression of glutaminase (GLS). Intestinal gluconeogenesis (IGN) is a process through which glutamine is turned into glucose in the small intestine, for which GLS is crucial. Animal studies suggest impaired IGN may have long-term effects on metabolic control and be associated with the development of type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). The aim of this...

Additional file 2 of Designing synthetic consortia of Trichoderma strains that improve antagonistic activities against pathogens and cucumber seedling growth

Dazhi Hao, Bo Lang, Yongkun Wang, Xinhua Wang, Tong Liu & Jie Chen
Additional file 2. Collection Proof of Strain CM100Z4.

Additional file 4 of Designing synthetic consortia of Trichoderma strains that improve antagonistic activities against pathogens and cucumber seedling growth

Dazhi Hao, Bo Lang, Yongkun Wang, Xinhua Wang, Tong Liu & Jie Chen
Additional file 4. Collection Proof of Strain SBW10264.

Additional file 5 of Designing synthetic consortia of Trichoderma strains that improve antagonistic activities against pathogens and cucumber seedling growth

Dazhi Hao, Bo Lang, Yongkun Wang, Xinhua Wang, Tong Liu & Jie Chen
Additional file 5. Collection Proof of Strain RW10569.

Comparing ‘clinical hunch’ against clinical decision support systems (PERC rule, wells score, revised Geneva score and YEARS criteria) in the diagnosis of acute pulmonary embolism

Koshiar Medson, Jimmy Yu, Lovisa Liwenborg, Peter Lindholm & Eli Westerlund
Abstract Background Pulmonary embolism (PE) is a common and potentially life-threatening condition. Since it is considered a ‘do not miss’ diagnosis, PE tends to be over-investigated beyond the evidence-based clinical decision support systems (CDSS), which in turn subjects patients to unnecessary radiation and contrast agent exposure with no apparent benefits in terms of outcome. The purpose of this study was to evaluate the yield of ‘clinical hunch’ (gestalt) and four CDSS: the PERC Rule, Wells...

Comparing ‘clinical hunch’ against clinical decision support systems (PERC rule, wells score, revised Geneva score and YEARS criteria) in the diagnosis of acute pulmonary embolism

Koshiar Medson, Jimmy Yu, Lovisa Liwenborg, Peter Lindholm & Eli Westerlund
Abstract Background Pulmonary embolism (PE) is a common and potentially life-threatening condition. Since it is considered a ‘do not miss’ diagnosis, PE tends to be over-investigated beyond the evidence-based clinical decision support systems (CDSS), which in turn subjects patients to unnecessary radiation and contrast agent exposure with no apparent benefits in terms of outcome. The purpose of this study was to evaluate the yield of ‘clinical hunch’ (gestalt) and four CDSS: the PERC Rule, Wells...

sj-docx-1-cic-10.1177_11795468221133611 – Supplemental material for XGBoost, A Novel Explainable AI Technique, in the Prediction of Myocardial Infarction: A UK Biobank Cohort Study

Alexander Moore & Max Bell
Supplemental material, sj-docx-1-cic-10.1177_11795468221133611 for XGBoost, A Novel Explainable AI Technique, in the Prediction of Myocardial Infarction: A UK Biobank Cohort Study by Alexander Moore and Max Bell in Clinical Medicine Insights: Cardiology

XGBoost, A Novel Explainable AI Technique, in the Prediction of Myocardial Infarction: A UK Biobank Cohort Study

Alexander Moore & Max Bell
We wanted to assess if “Explainable AI” in the form of extreme gradient boosting (XGBoost) could outperform traditional logistic regression in predicting myocardial infarction (MI) in a large cohort. Two machine learning methods, XGBoost and logistic regression, were compared in predicting risk of MI. The UK Biobank is a population-based prospective cohort including 502 506 volunteers with active consent, aged 40 to 69 years at recruitment from 2006 to 2010. These subjects were followed until...

XGBoost, A Novel Explainable AI Technique, in the Prediction of Myocardial Infarction: A UK Biobank Cohort Study

Alexander Moore & Max Bell
We wanted to assess if “Explainable AI” in the form of extreme gradient boosting (XGBoost) could outperform traditional logistic regression in predicting myocardial infarction (MI) in a large cohort. Two machine learning methods, XGBoost and logistic regression, were compared in predicting risk of MI. The UK Biobank is a population-based prospective cohort including 502 506 volunteers with active consent, aged 40 to 69 years at recruitment from 2006 to 2010. These subjects were followed until...

Association between brain volume and disability over time in multiple sclerosis

Thomas Moridi, Leszek Stawiarz, Kyla A McKay, Benjamin V Ineichen, Russell Ouellette, Daniel Ferreira, J-Sebastian Muehlboeck, Eric Westman, Ingrid Kockum, Tomas Olsson, Fredrik Piehl, Jan Hillert, Ali Manouchehrinia & Tobias Granberg
BackgroundMost previous multiple sclerosis (MS) brain atrophy studies using MS impact scale 29 (MSIS-29) or symbol digit modalities test (SDMT) have been cross-sectional with limited sets of clinical outcomes.ObjectivesTo investigate which brain and lesion volume metrics show the strongest long-term associations with the expanded disability status scale (EDSS), SDMT, and MSIS-29, and whether MRI-clinical associations vary with age.MethodsWe acquired MRI and clinical data from a real-world Swedish MS cohort. FreeSurfer and SPM Lesion Segmentation Tool...

Factors affecting the blockchain application in construction management in China: an ANP-SWOT hybrid approach

Yu Gao, Oskar Casasayas, Jiayuan Wang & Xiaoxiao Xu
As a decentralised ledger and data management technology, blockchain has attracted increasing interest and has been effectively applied in various areas. Despite its promising potential, there are few studies proposing effective strategies for promoting blockchain, particularly in providing a strategic analysis of blockchain in China's construction management. This study aims to investigate the external and internal environments of blockchain application and determine the roadmaps and strategies for blockchain application in construction management in China. A...

DNA methylation-based detection and prediction of cervical intraepithelial neoplasia grade 3 and invasive cervical cancer with the WID™-qCIN test

Chiara Herzog, Karin Sundström, Allison Jones, Iona Evans, James E. Barrett, Jiangrong Wang, Elisa Redl, Lena Schreiberhuber, Laura Costas, Sonia Paytubi, Lukas Dostalek, Michal Zikan, David Cibula, Gaby Sroczynski, Uwe Siebert, Joakim Dillner & Martin Widschwendter
Abstract Background Cervical screening using primary human papilloma virus (HPV) testing and cytology is being implemented in several countries. Cytology as triage for colposcopy referral suffers from several shortcomings. HPV testing overcomes some of these but lacks specificity in women under 30. Here, we aimed to develop and validate an automatable triage test that is highly sensitive and specific independently of age and sample heterogeneity, and predicts progression to CIN3+ in HPV+ patients. Results The...

DNA methylation-based detection and prediction of cervical intraepithelial neoplasia grade 3 and invasive cervical cancer with the WID™-qCIN test

Chiara Herzog, Karin Sundström, Allison Jones, Iona Evans, James E. Barrett, Jiangrong Wang, Elisa Redl, Lena Schreiberhuber, Laura Costas, Sonia Paytubi, Lukas Dostalek, Michal Zikan, David Cibula, Gaby Sroczynski, Uwe Siebert, Joakim Dillner & Martin Widschwendter
Abstract Background Cervical screening using primary human papilloma virus (HPV) testing and cytology is being implemented in several countries. Cytology as triage for colposcopy referral suffers from several shortcomings. HPV testing overcomes some of these but lacks specificity in women under 30. Here, we aimed to develop and validate an automatable triage test that is highly sensitive and specific independently of age and sample heterogeneity, and predicts progression to CIN3+ in HPV+ patients. Results The...

Additional file 1 of Evaluating women’s acceptability of treatment of incomplete second trimester abortion using misoprostol provided by midwives compared with physicians: a mixed methods study

Susan Atuhairwe, Claudia Hanson, Lynn Atuyambe, Josaphat Byamugisha, Nazarius Mbona Tumwesigye, Ronald Ssenyonga & Kristina Gemzell-Danielsson
Additional file 1. In depth-interview respondents’ characteristics.

Evaluating women’s acceptability of treatment of incomplete second trimester abortion using misoprostol provided by midwives compared with physicians: a mixed methods study

Susan Atuhairwe, Claudia Hanson, Lynn Atuyambe, Josaphat Byamugisha, Nazarius Mbona Tumwesigye, Ronald Ssenyonga & Kristina Gemzell-Danielsson
Abstract Background Studies evaluating task sharing in postabortion care have mainly focused on women in first trimester and many lack a qualitative component. We aimed to evaluate patient acceptability of treatment of incomplete second trimester abortion using misoprostol provided by midwives compared with physicians and also gained a deeper understanding of the patients’ lived treatment experiences in Uganda. Methods Our mixed methods study combined 1140 structured interview data from a randomized controlled equivalence trial and...

Evaluating women’s acceptability of treatment of incomplete second trimester abortion using misoprostol provided by midwives compared with physicians: a mixed methods study

Susan Atuhairwe, Claudia Hanson, Lynn Atuyambe, Josaphat Byamugisha, Nazarius Mbona Tumwesigye, Ronald Ssenyonga & Kristina Gemzell-Danielsson
Abstract Background Studies evaluating task sharing in postabortion care have mainly focused on women in first trimester and many lack a qualitative component. We aimed to evaluate patient acceptability of treatment of incomplete second trimester abortion using misoprostol provided by midwives compared with physicians and also gained a deeper understanding of the patients’ lived treatment experiences in Uganda. Methods Our mixed methods study combined 1140 structured interview data from a randomized controlled equivalence trial and...

High levels of health-related quality of life five years after curative treatment of prostate cancer with HDR-brachytherapy and external beam radiation

Marie Hjälm-Eriksson, Anders Ullén, Sten Nilsson, Hemming Johansson, Josef Nilsson, Enrique Castellanos & Yvonne Brandberg
The aim of this cross-sectional study was to investigate long-term health-related quality of life (HRQoL) in men with prostate cancer treated 2002–2008 with external beam radiotherapy (EBRT) combined with high dose-rate brachytherapy (HDRBT), Cohort A, and to compare these data with age-adjusted normative data. In addition, differences in HRQoL following adjustments of the brachytherapy technique in 2001 were investigated by comparing Cohort A with men treated at the same clinic from 1998-2000, Cohort B. Cohort...

Incidence, mortality and relative survival of patients with cancer of the bladder and upper urothelial tract in the Nordic countries between 1990 and 2019

Eemil Karttunen, Petteri Hervonen, Abolfazl Hosseini Aliabad, Jan Oldenburg, Helle Pappot, Jukka Sairanen, Henrik Støvring, Juan Luis Vásquez, Suzanne Bergman, Gry Magnussen, Pernille Norremark, Steinar Thoresen & Anders Ullén
To understand the potential impact of new treatment options for urinary tract cancer, recent population trends in incidence, mortality and survival should be elucidated. This study estimated changes in the incidence, mortality and relative survival of urinary tract cancer in the Nordic countries (Denmark, Finland, Iceland, Norway and Sweden) between 1990 and 2019. Annual counts of incident cases and deaths due to urinary tract cancer (International Classification of Diseases, Tenth Revision, Clinical Modification codes C65–C68,...

sj-pdf-1-hol-10.1177_09596836221131698 – Supplemental material for Understanding the transport networks complex between South Asia, Southeast Asia and China during the late Neolithic and Bronze Age

Minmin Ma, Yongxiu Lu, Guanghui Dong, Lele Ren, Rui Min, Lihong Kang, Zhonghua Zhu, Xiaorui Li, Bo Li, Zhijian Yang, Nongbu Cili, Ruiliang Liu, Yu Gao & Fahu Chen
Supplemental material, sj-pdf-1-hol-10.1177_09596836221131698 for Understanding the transport networks complex between South Asia, Southeast Asia and China during the late Neolithic and Bronze Age by Minmin Ma, Yongxiu Lu, Guanghui Dong, Lele Ren, Rui Min, Lihong Kang, Zhonghua Zhu, Xiaorui Li, Bo Li, Zhijian Yang, Nongbu Cili, Ruiliang Liu, Yu Gao and Fahu Chen in The Holocene

Additional file 1 of Speed of cooling after cardiac arrest in relation to the intervention effect: a sub-study from the TTM2-trial

Rupert F. G. Simpson, Josef Dankiewicz, Grigoris V. Karamasis, Paolo Pelosi, Matthias Haenggi, Paul J. Young, Janus Christian Jakobsen, Jonathan Bannard-Smith, Pedro D. Wendel-Garcia, Fabio Silvio Taccone, Per Nordberg, Matt P. Wise, Anders M. Grejs, Gisela Lilja, Roy Bjørkholt Olsen, Alain Cariou, Jean Baptiste Lascarrou, Manoj Saxena, Jan Hovdenes, Matthew Thomas, Hans Friberg, John R. Davies, Niklas Nielsen & Thomas R. Keeble
Additional file 1: Fig. 1. Predicted probability of death across the 6 hypothermia groups as compared to the normothermia groups at the corresponding sites. Patients in group 1, with the lowest average temperature at 4 hours had a higher probability of death.

Additional file 4 of Reporting unit context data to stakeholders in long-term care: a practical approach

Lisa A. Cranley, T K T Lo, Lori E. Weeks, Matthias Hoben, Liane R. Ginsburg, Malcolm Doupe, Ruth A. Anderson, Adrian Wagg, Anne-Marie Boström, Carole A. Estabrooks & Peter G. Norton
Additional file 4. Regression analysis- full models. Provides details of full models of associations between context rank summary scores and outcomes (Table 4) and associations between binary scores and outcomes (Table 5).

Additional file 3 of Reporting unit context data to stakeholders in long-term care: a practical approach

Lisa A. Cranley, T K T Lo, Lori E. Weeks, Matthias Hoben, Liane R. Ginsburg, Malcolm Doupe, Ruth A. Anderson, Adrian Wagg, Anne-Marie Boström, Carole A. Estabrooks & Peter G. Norton
Additional file 3. Focus group question guide. A semi-structured focus group guide used with nursing home leaders.

Registration Year

  • 2022
    223

Resource Types

  • Text
    122
  • Collection
    60
  • Dataset
    31
  • Image
    10

Affiliations

  • Karolinska University Hospital
    223
  • Karolinska Institute
    203
  • Huazhong University of Science and Technology
    49
  • Zhejiang University
    43
  • Fudan University
    43
  • Capital Medical University
    37
  • Jilin University
    25
  • Shandong Agricultural University
    25
  • Shanghai Jiao Tong University
    20
  • West China Hospital of Sichuan University
    18