3 Works

Sex-dimorphic effects of Biogenesis of Lysosome-related Organelles Complex-1 (BLOC-1) deficiency on mouse perinatal brain development

Cristina Ghiani & Esteban Dell'Angelica
The function(s) of the Biogenesis of Lysosome-related Organelles Complex 1 (BLOC-1) during brain development is hitherto largely unknown. Here, we investigated how its absence alters the trajectory of postnatal brain development using as model the pallid mouse. Most of the defects observed early postnatally in the mutant mice were more prominent in males than in females and in the hippocampus. Male mutant mice, but not females, had smaller brains as compared to sex-matching wild-types at...

Data from: Markov-modulated continuous-time Markov chains to identify site- and branch-specific evolutionary variation in BEAST

Guy Baele, Mandev Gill, Paul Bastide, Philippe Lemey & Marc Suchard
Markov models of character substitution on phylogenies form the foundation of phylogenetic inference frameworks. Early models made the simplifying assumption that the substitution process is homogeneous over time and across sites in the molecular sequence alignment. While standard practice adopts extensions that accommodate heterogeneity of substitution rates across sites, heterogeneity in the process over time in a site-specific manner remains frequently overlooked. This is problematic, as evolutionary processes that act at the molecular level are...

Data from: A search for technosignatures from TRAPPIST-1, LHS 1140, and 10 planetary systems in the Kepler field with the Green Bank Telescope at 1.15–1.73 GHz

Jean-Luc Margot, Pavlo Pinchuk, Adam H. Greenberg, Thomas Ayalde, Chad Bloxham, Arjun Boddu, Luis Gerardo Chinchilla-Garcia, Micah Cliffe, Sara Gallagher, Kira Hart, Brayden Hesford, Inbal Mizrahi, Ruth Pike, Dominic Rodger, Bade Sayki, Una Schneck, Aysen Tan, & Ryan S. Lynch
This dataset includes candidate signal detections obtained at the Green Bank Telescope in 2017 and reprocessed with the 2020 UCLA SETI Group data processing pipeline. As part of our ongoing search for technosignatures, we collected over three terabytes of data in May 2017 with the L-band receiver (1.15–1.73 GHz) of the 100 m diameter Green Bank Telescope. These observations focused primarily on planetary systems in the Kepler field, but also included scans of the recently...

Registration Year

  • 2020

Resource Types

  • Dataset


  • David Geffen School of Medicine at UCLA
  • University of California Los Angeles
  • University of Montpellier
  • KU Leuven