14 Works

Additional file 1 of Ewing sarcoma with very late metastasis in the skull: a case report

Ryota Hagihara, Hidetaka Arishima, Takahiro Yamauchi, Satoshi Kawajiri, Tomomi Ito, Mana Fukushima & Kenichiro Kikuta
Additional file 1: Table S1. Summary of late local recurrence or metastasis of Ewing sarcoma family of tumors [see Addtional file 1]. LR local recurrence; M metastases; ANED alive no evidence of disease; AWED alive with evidence of disease.

Simultaneous measurement of the size and methylation of chromosome 4qA-D4Z4 repeats in facioscapulohumeral muscular dystrophy by long-read sequencing

Yosuke Hiramuki, Yuriko Kure, Yoshihiko Saito, Megumu Ogawa, Keiko Ishikawa, Madoka Mori-Yoshimura, Yasushi Oya, Yuji Takahashi, Dae-Seong Kim, Noriko Arai, Chiaki Mori, Tsuyoshi Matsumura, Tadanori Hamano, Kenichiro Nakamura, Koji Ikezoe, Shinichiro Hayashi, Yuichi Goto, Satoru Noguchi & Ichizo Nishino
Abstract Background Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant muscular disorder characterized by asymmetric muscle wasting and weakness. FSHD can be subdivided into two types: FSHD1, caused by contraction of the D4Z4 repeat on chromosome 4q35, and FSHD2, caused by mild contraction of the D4Z4 repeat plus aberrant hypomethylation mediated by genetic variants in SMCHD1, DNMT3B, or LRIF1. Genetic diagnosis of FSHD is challenging because of the complex procedures required. Methods We applied Nanopore...

Additional file 1 of Simultaneous measurement of the size and methylation of chromosome 4qA-D4Z4 repeats in facioscapulohumeral muscular dystrophy by long-read sequencing

Yosuke Hiramuki, Yuriko Kure, Yoshihiko Saito, Megumu Ogawa, Keiko Ishikawa, Madoka Mori-Yoshimura, Yasushi Oya, Yuji Takahashi, Dae-Seong Kim, Noriko Arai, Chiaki Mori, Tsuyoshi Matsumura, Tadanori Hamano, Kenichiro Nakamura, Koji Ikezoe, Shinichiro Hayashi, Yuichi Goto, Satoru Noguchi & Ichizo Nishino
Additional file 1: Fig. S1. Characteristic sequences detected by nCATS. Sequences of representative (A) 4qA- and (B) 10q-derived reads obtained from the indicated samples. The XapI/non-XapI and BlnI/non-BlnI sites in the most distal D4Z4 RU are shown. In Samples 8, 14, and 15, the XapI, XapI and non-BlnI, and non-XapI sites, respectively, in the second most distal D4Z4 RU are shown, due to the difficulty in identifying restriction sites. Table S1. Lengths of reads derived...

Additional file 1 of Simultaneous measurement of the size and methylation of chromosome 4qA-D4Z4 repeats in facioscapulohumeral muscular dystrophy by long-read sequencing

Yosuke Hiramuki, Yuriko Kure, Yoshihiko Saito, Megumu Ogawa, Keiko Ishikawa, Madoka Mori-Yoshimura, Yasushi Oya, Yuji Takahashi, Dae-Seong Kim, Noriko Arai, Chiaki Mori, Tsuyoshi Matsumura, Tadanori Hamano, Kenichiro Nakamura, Koji Ikezoe, Shinichiro Hayashi, Yuichi Goto, Satoru Noguchi & Ichizo Nishino
Additional file 1: Fig. S1. Characteristic sequences detected by nCATS. Sequences of representative (A) 4qA- and (B) 10q-derived reads obtained from the indicated samples. The XapI/non-XapI and BlnI/non-BlnI sites in the most distal D4Z4 RU are shown. In Samples 8, 14, and 15, the XapI, XapI and non-BlnI, and non-XapI sites, respectively, in the second most distal D4Z4 RU are shown, due to the difficulty in identifying restriction sites. Table S1. Lengths of reads derived...

Ewing sarcoma with very late metastasis in the skull: a case report

Ryota Hagihara, Hidetaka Arishima, Takahiro Yamauchi, Satoshi Kawajiri, Tomomi Ito, Mana Fukushima & Kenichiro Kikuta
Abstract Background Ewing sarcoma is a malignant bone tumor; however, its prognosis has improved since the development of modern chemotherapy. Although Ewing sarcoma outcomes have improved, issues related to late complications, secondary malignant neoplasms, and late recurrence or metastasis have emerged. Case presentation We report a case of Ewing sarcoma that recurred in the occipital bone 21 years after primary tumor treatment. A 45-year-old Japanese woman with a history of Ewing sarcoma 21 years prior,...

Additional file 2 of Randomized controlled trials in de-implementation research: a systematic scoping review

Aleksi J. Raudasoja, Petra Falkenbach, Robin W. M. Vernooij, Jussi M. J. Mustonen, Arnav Agarwal, Yoshitaka Aoki, Marco H. Blanker, Rufus Cartwright, Herney A. Garcia-Perdomo, Tuomas P. Kilpeläinen, Olli Lainiala, Tiina Lamberg, Olli P. O. Nevalainen, Eero Raittio, Patrick O. Richard, Philippe D. Violette, Jorma Komulainen, Raija Sipilä & Kari A. O. Tikkinen
Additional file 2. Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) Checklist.

Additional file 1 of Ewing sarcoma with very late metastasis in the skull: a case report

Ryota Hagihara, Hidetaka Arishima, Takahiro Yamauchi, Satoshi Kawajiri, Tomomi Ito, Mana Fukushima & Kenichiro Kikuta
Additional file 1: Table S1. Summary of late local recurrence or metastasis of Ewing sarcoma family of tumors [see Addtional file 1]. LR local recurrence; M metastases; ANED alive no evidence of disease; AWED alive with evidence of disease.

Additional file 1 of Randomized controlled trials in de-implementation research: a systematic scoping review

Aleksi J. Raudasoja, Petra Falkenbach, Robin W. M. Vernooij, Jussi M. J. Mustonen, Arnav Agarwal, Yoshitaka Aoki, Marco H. Blanker, Rufus Cartwright, Herney A. Garcia-Perdomo, Tuomas P. Kilpeläinen, Olli Lainiala, Tiina Lamberg, Olli P. O. Nevalainen, Eero Raittio, Patrick O. Richard, Philippe D. Violette, Jorma Komulainen, Raija Sipilä & Kari A. O. Tikkinen
Additional file 1: eFigure1. Flow diagram. eFigure 2. Published studies per medical content area. eFigure 3. Risk of bias per question. eFigure 4. Risk of bias inside intervention categories. eFigure 5. Intervention components in single-component interventions. eMethods 1. Search strategies. eMethods 2. Risk of Bias Tool for RCTs of complex interventions. eMethods 3. Refined version of intervention taxonomy for de-implementation interventions. eMethods 4. Rationale for refined intervention taxonomy. eMethods 5. Rationale for outcome hierarchy of...

Ewing sarcoma with very late metastasis in the skull: a case report

Ryota Hagihara, Hidetaka Arishima, Takahiro Yamauchi, Satoshi Kawajiri, Tomomi Ito, Mana Fukushima & Kenichiro Kikuta
Abstract Background Ewing sarcoma is a malignant bone tumor; however, its prognosis has improved since the development of modern chemotherapy. Although Ewing sarcoma outcomes have improved, issues related to late complications, secondary malignant neoplasms, and late recurrence or metastasis have emerged. Case presentation We report a case of Ewing sarcoma that recurred in the occipital bone 21 years after primary tumor treatment. A 45-year-old Japanese woman with a history of Ewing sarcoma 21 years prior,...

Simultaneous measurement of the size and methylation of chromosome 4qA-D4Z4 repeats in facioscapulohumeral muscular dystrophy by long-read sequencing

Yosuke Hiramuki, Yuriko Kure, Yoshihiko Saito, Megumu Ogawa, Keiko Ishikawa, Madoka Mori-Yoshimura, Yasushi Oya, Yuji Takahashi, Dae-Seong Kim, Noriko Arai, Chiaki Mori, Tsuyoshi Matsumura, Tadanori Hamano, Kenichiro Nakamura, Koji Ikezoe, Shinichiro Hayashi, Yuichi Goto, Satoru Noguchi & Ichizo Nishino
Abstract Background Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant muscular disorder characterized by asymmetric muscle wasting and weakness. FSHD can be subdivided into two types: FSHD1, caused by contraction of the D4Z4 repeat on chromosome 4q35, and FSHD2, caused by mild contraction of the D4Z4 repeat plus aberrant hypomethylation mediated by genetic variants in SMCHD1, DNMT3B, or LRIF1. Genetic diagnosis of FSHD is challenging because of the complex procedures required. Methods We applied Nanopore...

Additional file 2 of Randomized controlled trials in de-implementation research: a systematic scoping review

Aleksi J. Raudasoja, Petra Falkenbach, Robin W. M. Vernooij, Jussi M. J. Mustonen, Arnav Agarwal, Yoshitaka Aoki, Marco H. Blanker, Rufus Cartwright, Herney A. Garcia-Perdomo, Tuomas P. Kilpeläinen, Olli Lainiala, Tiina Lamberg, Olli P. O. Nevalainen, Eero Raittio, Patrick O. Richard, Philippe D. Violette, Jorma Komulainen, Raija Sipilä & Kari A. O. Tikkinen
Additional file 2. Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) Checklist.

Randomized controlled trials in de-implementation research: a systematic scoping review

Aleksi J. Raudasoja, Petra Falkenbach, Robin W. M. Vernooij, Jussi M. J. Mustonen, Arnav Agarwal, Yoshitaka Aoki, Marco H. Blanker, Rufus Cartwright, Herney A. Garcia-Perdomo, Tuomas P. Kilpeläinen, Olli Lainiala, Tiina Lamberg, Olli P. O. Nevalainen, Eero Raittio, Patrick O. Richard, Philippe D. Violette, Jorma Komulainen, Raija Sipilä & Kari A. O. Tikkinen
Abstract Background Healthcare costs are rising, and a substantial proportion of medical care is of little value. De-implementation of low-value practices is important for improving overall health outcomes and reducing costs. We aimed to identify and synthesize randomized controlled trials (RCTs) on de-implementation interventions and to provide guidance to improve future research. Methods MEDLINE and Scopus up to May 24, 2021, for individual and cluster RCTs comparing de-implementation interventions to usual care, another intervention, or...

Additional file 1 of Randomized controlled trials in de-implementation research: a systematic scoping review

Aleksi J. Raudasoja, Petra Falkenbach, Robin W. M. Vernooij, Jussi M. J. Mustonen, Arnav Agarwal, Yoshitaka Aoki, Marco H. Blanker, Rufus Cartwright, Herney A. Garcia-Perdomo, Tuomas P. Kilpeläinen, Olli Lainiala, Tiina Lamberg, Olli P. O. Nevalainen, Eero Raittio, Patrick O. Richard, Philippe D. Violette, Jorma Komulainen, Raija Sipilä & Kari A. O. Tikkinen
Additional file 1: eFigure1. Flow diagram. eFigure 2. Published studies per medical content area. eFigure 3. Risk of bias per question. eFigure 4. Risk of bias inside intervention categories. eFigure 5. Intervention components in single-component interventions. eMethods 1. Search strategies. eMethods 2. Risk of Bias Tool for RCTs of complex interventions. eMethods 3. Refined version of intervention taxonomy for de-implementation interventions. eMethods 4. Rationale for refined intervention taxonomy. eMethods 5. Rationale for outcome hierarchy of...

Randomized controlled trials in de-implementation research: a systematic scoping review

Aleksi J. Raudasoja, Petra Falkenbach, Robin W. M. Vernooij, Jussi M. J. Mustonen, Arnav Agarwal, Yoshitaka Aoki, Marco H. Blanker, Rufus Cartwright, Herney A. Garcia-Perdomo, Tuomas P. Kilpeläinen, Olli Lainiala, Tiina Lamberg, Olli P. O. Nevalainen, Eero Raittio, Patrick O. Richard, Philippe D. Violette, Jorma Komulainen, Raija Sipilä & Kari A. O. Tikkinen
Abstract Background Healthcare costs are rising, and a substantial proportion of medical care is of little value. De-implementation of low-value practices is important for improving overall health outcomes and reducing costs. We aimed to identify and synthesize randomized controlled trials (RCTs) on de-implementation interventions and to provide guidance to improve future research. Methods MEDLINE and Scopus up to May 24, 2021, for individual and cluster RCTs comparing de-implementation interventions to usual care, another intervention, or...

Registration Year

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Affiliations

  • University of Fukui
    14
  • University of Valle
    6
  • Université de Sherbrooke
    6
  • University of Groningen
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  • Centre Hospitalier Universitaire de Sherbrooke
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  • McMaster University
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  • Chelsea and Westminster Hospital NHS Foundation Trust
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  • Tampere University
    6
  • University of Toronto
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  • University of Oulu
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