2 Works

Data from: Different effects of paternal trans-generational immune priming on survival and immunity in step and genetic offspring

Hendrik Eggert, Joachim Kurtz & Maike F. Diddens-De Buhr
Paternal trans-generational immune priming, whereby fathers provide immune protection to offspring, has been demonstrated in the red flour beetle Tribolium castaneum exposed to the insect pathogen Bacillus thuringiensis. It is currently unclear how such protection is transferred, as in contrast to mothers, fathers do not directly provide offspring with a large amount of substances. In addition to sperm, male flour beetles transfer seminal fluids in a spermatophore to females during copulation. Depending on whether paternal...

Data from: Macrophages contribute to the cyclic activation of adult hair follicle stem cells

Donatello Castellana, Ralf Paus & Mirna Perez-Moreno
Skin epithelial stem cells operate within a complex signaling milieu that orchestrates their lifetime regenerative properties. The question of whether and how immune cells impact on these stem cells within their niche is not well understood. Here we show that skin-resident macrophages decrease in number because of apoptosis before the onset of epithelial hair follicle stem cell activation during the murine hair cycle. This process is linked to distinct gene expression, including Wnt transcription. Interestingly,...

Registration Year

  • 2014

Resource Types

  • Dataset


  • University of M√ľnster
  • Spanish National Cancer Research Centre
  • University of Manchester