45 Works

Data from: Multi-scale quantification of tissue behavior during amniote embryo axis elongation

Bertrand Benazeraf, Mathias Beaupeux, Martin Tcherknookov, Allison Wallingford, Tasha Salisbury, Amelia Shirtz, Andrew Shirtz, David Huss, Olivier Pourquie, Paul Francois & Rusty Lansford
Embryonic axis elongation is a complex multi-tissue morphogenetic process responsible for the formation of the posterior part of the amniote body. How movements and growth are coordinated between the different posterior tissues (e.g. neural tube, axial and paraxial mesoderm, lateral plate, ectoderm, endoderm) to drive axis morphogenesis remain largely unknown. Here, we use quail embryos to quantify cell behavior and tissue movements during elongation. We quantify the tissue-specific contribution to axis elongation by using 3D...

Data from: A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1

Renaud Prudent, Nathalie Demoncheaux, Hélène Diemer, Véronique Collin-Faure, Reuben Kapur, Fabrice Paublant, Laurence Lafanechère, Sarah Cianférani & Thierry Rabilloud
LIM kinases are located at a strategic crossroad, downstream of several signaling pathways and upstream of effectors such as microtubules and the actin cytoskeleton. Cofilin is the only LIM kinases substrate that is well described to date, and its phosphorylation on serine 3 by LIM kinases controls cofilin actin-severing activity. Consequently, LIM kinases inhibition leads to actin cytoskeleton disorganization and blockade of cell motility, which makes this strategy attractive in anticancer treatments. LIMK has also...

Data from: Regional paleoclimates and local consequences: Integrating GIS analysis of diachronic settlement patterns and process-based agroecosystem modeling of potential agricultural productivity in Provence (France)

Daniel Contreras, Eneko Hiriart, Alberte Bondeau, Alan Kirman, Joël Guiot, Loup Bernard, Romain Suarez, Sander Van Der Leeuw & Daniel A. Contreras
Holocene climate variability in the Mediterranean Basin is often cited as a potential driver of societal change, but the mechanisms of this putative influence are generally little explored. In this paper we integrate two tools - agro-ecosystem modeling of potential agricultural yields and spatial analysis of archaeological settlement pattern data - in order to examine the human consequences of past climatic changes. Focusing on a case study in Provence (France), we adapt an agro-ecosystem model...


Julie Glikman, Gabriella Parussa & Richard Waltereit
Studia linguistica romanica, 2019(2), 1-6

Data from: Oceanic thermal structure mediates dive sequences in a foraging seabird

Xavier Meyer, Andrew MacIntosh, André Chiaradia, Akiko Kato, Francisco Ramírez, Cedric Sueur & Yan Ropert-Coudert
1. Changes in marine ecosystems are easier to detect in upper-level predators, like seabirds, which integrate trophic interactions throughout the food web. 2. Here, we examined whether diving parameters and complexity in the temporal organisation of foraging sequences of little penguins (Eudyptula minor) are influenced by sea surface temperature (SST), water stratification and wind speed – three oceanographic features influencing prey abundance and distribution in the water column. 3. Using fractal time series analysis, we...

The fast and the curious II: performance, personality and metabolism in Karoo bush rats

Paul Agnani, Jennifer Thomson, Carsten Schradin & Vincent Careau
Personality traits (e.g., activity, exploration, boldness) are frequently correlated with each other and with various other traits of biological importance. According to the performance, allocation, and independent models of energy management, the relationship between personality traits and resting metabolic rate (RMR) is predicted to be either positive, negative, or nil. As for the relationship between personality traits and locomotor performance, the trait compensation and co-specialisation hypotheses respectively predict a positive and negative relationship. To test...

Compte rendu Anne Carlier, Céline Guillot-Barbance (éds.) 2018. Latin tardif, français ancien. Continuités et ruptures. Berlin : De Gruyter

Julie Glikman
Studia linguistica romanica 2022.7, 126-140

Induced micro-seismicity monitoring in urban context using seismic arrays

Rémi Fiori , Jérôme Vergne , Jean Schmittbuhl , Dimitri Zigone & Sophie Lambotte
The modification of the stress field induced by fluid injection into the ground can generate seismic motions. Their monitoring is a key point to limit the occurrence of impacting events. Generally, this is performed using seismic surface networks, which can be limited by a significant ambient noise level especially in urban contexts. An alternative consists in the installation of stations in the depth of wells to increase the distance with surface ambient noise sources. However,...

Wide spectrum and high frequency of genomic structural variation, including transposable elements, in large double stranded DNA viruses

Clement Gilbert, Elisabeth Herniou, Yannis Moreau, Nicolas Lévêque, Carine Meignin, Laurent Daeffler, Brian Federici, Richard Cordaux & Vincent Loiseau
Our knowledge of the diversity and frequency of genomic structural variation segregating in populations of large double stranded (ds) DNA viruses is limited. Here we sequenced the genome of a baculovirus (AcMNPV) purified from beet armyworm (Spodoptera exigua) larvae at depths >195,000X using both short-read (Illumina) and long-read (PacBio) technologies. Using a pipeline relying on hierarchical clustering of structural variants (SVs) detected in individual short- and long-reads by six variant callers, we identified a total...

Data from: Glucocorticoid levels predict subsequent social tactic in females of a facultatively social mammal

Davina Hill, Neville Pillay & Carsten Schradin
Facultatively social species, in which individuals can switch between group- and solitary-living tactics, offer an opportunity to shed light on proximate mechanisms underlying alternative life histories. Promising hormonal mediators of social tactic include glucocorticoids, which control energy allocation and are negatively related to body condition, and testosterone which regulates numerous social behaviours. Here, we investigated hormonal profiles associated with social tactic in eight generations of free-living female striped mice (Rhabdomys pumilio). Females are group living...

Les dynamiques sociales et leurs conflits: mobilisations, régulations, représentations

Myriam Klinger & Sébastien Schehr

Latest results from the hybrid micro-gravity monitoring of the Theistareykir geothermal field (North Iceland)

Nolwenn Portier , Jacques Hinderer , Florian Schäfer , Philippe Jousset , Kemal Erbas , Vincent Drouin , Vincent Drouin , Freysteinn Sigmundsson , Ingwar Magnusson , Gylfi Pall Hersir , Kristjan Agustsson , Agrismur Gudmundsson , Egill Juliusson , Hreinn Hjartasson , Hreinn Hjartasson & Jean-Daniel Bernard
Geothermal energy represents around 30% of the produced electricity in Iceland with a cumulative capacity being equal to 755 MWe (Ragnarsson et al., 2020). In particular, the Theistareykir geothermal plant, which is located on the Mid-Atlantic ridge in North Iceland, produces 90 MWe using two turbines in operation since autumn 2017 and spring 2018, respectively. We will report on the hybrid micro-gravity monitoring and discuss how this technique will contribute to the sustainable management of...

Data from: The evolution of dual meat and milk cattle husbandry in Linearbandkeramik societies

Rosalind E. Gillis, Lenka Kovačiková, Stéphanie Brehard, Emilie Guthmann, Ivana Vostrovská, Hana Nohálová, Rose-Marie Arbogast, László Domboróczki, Joachim Pechtl, Alexandra Anders, Arkadiusz Marciniak, Anne Tresset & Jean-Denis Vigne
Cattle dominate archaeozoological assemblages from the north-central Europe between the sixth and fifth millennium BC and are frequently considered as exclusively used for their meat. Dairy products may have played a greater role than previously believed. Selective pressure on the lactase persistence mutation has been modelled to have begun between 6000 and 4000 years ago in central Europe. The discovery of milk lipids in late sixth millennium ceramic sieves in Poland may reflect an isolated...

French Global Network of Geomagnetic observatories

The Bureau Central de Magnétisme Terrestre (BCMT) is a French organization founded in 1921 and attached to the Institut de Physique du Globe de Paris (IPGP). Two French institutions are involved in BCMT operations: IPGP and École et Observatoire des Sciences de la Terre de Strasbourg (EOST). The primary mission of the BCMT is to provide ground geomagnetic observations of the highest quality to the scientific community, in France and abroad. To achieve its mission,...

French Global Network of Geomagnetic observatories

The Bureau Central de Magnétisme Terrestre (BCMT) is a French organization founded in 1921 and attached to the Institut de Physique du Globe de Paris (IPGP). Two French institutions are involved in BCMT operations: IPGP and École et Observatoire des Sciences de la Terre de Strasbourg (EOST). The primary mission of the BCMT is to provide ground geomagnetic observations of the highest quality to the scientific community, in France and abroad. To achieve its mission,...

Natural history, phenotypic spectrum, and discriminative features of multisystemic RFC1-disease

Andreas Traschütz, Andrea Cortese, Selina Reich, Natalia Dominik, Jennifer Faber, Heike Jacobi, Annette Hartmann, Dan Rujescu, Solveig Montaut, Andoni Echaniz-Laguna, Sevda Erer, Valerie Cornelia Schütz, Alexander Tarnutzer, Marc Sturm, Tobias Haack, Nadège Vaucamps-Diedhiou, Helene Puccio, Ludger Schöls, Thomas Klockgether, Bart P. Van De Warrenburg, Martin Paucar, Dagmar Timmann, Ralf-Dieter Hilgers, Jose Gazulla, Michael Strupp … & Matthis Synofzik
Objective: To delineate the full phenotypic spectrum, discriminative features, piloting longitudinal progression data, and sample size calculations of RFC1-repeat expansions, recently identified as causing cerebellar ataxia, neuropathy, vestibular areflexia syndrome (CANVAS). Methods: Multimodal RFC1 repeat screening (PCR, southern blot, whole-exome/genome (WES/WGS)-based approaches) combined with cross-sectional and longitudinal deep-phenotyping in (i) cross-European cohort A (70 families) with ≥2 features of CANVAS and/or ataxia-with-chronic-cough (ACC); and (ii) Turkish cohort B (105 families) with unselected late-onset ataxia. Results:...

Peau et borréliose de Lyme : opportunités et challenges pour le développement d’un nouveau diagnostic par protéomique

Laurence SABATIER & Nathalie Boulanger
L’interface cutanée joue un rôle clef dans les maladies à transmission vectorielle comme le paludisme, la leishmaniose, la trypanosomiase ou la borréliose de Lyme. A ce niveau, l’arthropode (tique ou l’insecte) pique et inocule sa salive, en même temps que des pathogènes s’il est infecté. Le plus souvent, une réaction inflammatoire se développe, plus ou moins caractéristique. Jusqu’à présent, la peau a souvent été occultée dans la physiopathologie de ces maladies. La borréliose de Lyme...

Data from: Social transmission in the wild reduces predation pressure on novel prey signals

Liisa Hämäläinen, William Hoppitt, Hannah Rowland, Johanna Mappes, Anthony Fulford, Sebastian Sosa & Rose Thorogood
Social transmission of information is taxonomically widespread and could have profound effects on the ecological and evolutionary dynamics of animal communities. Demonstrating this in the wild, however, has been challenging. Here we show by field experiment that social transmission among predators can shape how selection acts on prey defences. Using artificial prey and a novel approach in statistical analyses of social networks, we find that blue tit (Cyanistes caeruleus) and great tit (Parus major) predators...

Energy analysis of microseismicity induced byfluid-injection in the Soultz-sous-Forˆets geothermalreservoir

Kamel Drif , Olivier Lengliné , Jannes Kinscher & Jean Schmittbuhl
Between 1993 and 2005, the Soultz-sous-Forˆets reservoir was stimulated through 4 different wells crossing the reservoir at two different levels R3 (about 3km deep) and R5 (about 5km deep). The figure below represents the N-S section of the reservoir with the geometry of the 4 wells. During these stimulation episodes, seismic and hydraulic data were recorded. Using hydraulic data (pressure and flow rate) and available seismic catalogs of the stimulation episodes in the Soultz-sous-Forˆets reservoir,...

Cellules souches somatiques et hématopoïèse chez le mollusque

Patricia Cavelier, Julien Cau, Jean Marc Strub, Mohamed Jemaa, Nathalie Morin & Claude Delsert
L’origine du renouvellement des tissus fait débat chez le mollusque car aucune évidence de cellules souches n’a été montrée à ce jour au sein de ce vaste phylum. Cette question est d’autant plus fondamentale que la croissance se fait tout au long de la vie du mollusque et que ce groupe renferme les animaux vivants les plus vieux connus, tels ces spécimens du bivalve Arctica islandica âgés de plus de 500 ans. Par ailleurs, l’origine...

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  • University of Strasbourg
  • Institut De Physique Du Globe De Paris
  • Commissariat à L'Énergie Atomique (CEA)
  • Université de Strasbourg
  • Université d'Antananarivo, Madagascar
  • Vietnamese Academy Of Science And Technology (VAST), Vietnam
  • University of Reims Champagne-Ardenne
  • Centre National de la Recherche Scientifique - Institut National des Sciences de l'Univers (CNRS-INSU), France
  • Helmholtz Centre Potsdam - GFZ German Research Centre for Geosciences
  • Université Paris Cité