3 Works

Quantification of Bone Marrow Compartments in Histological Sections

Josefine Tratwal & Olaia Naveiras
We report the development of a semi-automated image analysis plug-in, MarrowQuant, which employs the open-source software QuPath, to systematically quantify multiple bone components in H&E sections in an unbiased manner. MarrowQuant discerns and quantifies the areas occupied by bone, adipocyte ghosts, hematopoietic cells and the interstitial/microvascular compartment. A separate feature, AdipoQuant, fragments adipocyte ghosts in H&E-stained sections of extramedullary adipose tissue sections to render adipocyte area and size distribution. Quantification of BM hematopoietic cellularity with...

Observational study over 8-year period evaluating microbiological characteristics and risk factor for isolation of multidrug-resistant organisms (MDRO) in patients with healthcare-associated infections (HAIs) hospitalized in a urology ward in Urogenital Infections and Inflammations

José Medina-Polo, Javier Gil-Moradillo, Alejandro González-Díaz, Pablo Abad-López, Rocío Santos-Pérez de la Blanca, Mario Hernández-Arroyo, Helena Peña-Vallejo, Julio Téigell-Tobar, Cristina Calzas-Montalvo, Prado Caro-González, Natalia Miranda-Utrera & Ángel Tejido-Sánchez
Objective: To analyze, in a urology ward, the prevalence and characteristics of healthcare-associated infections (HAIs) due to multidrug-resis­tant organisms (MDRO). Methods: We carried out an observational study from 2012 to 2019, evaluating MDRO among patients with HAIs, who were hospitalized in the urology ward. MDRO include Pseudomonas spp., resistant to at least three antibiotic groups, extended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae or those resistant to carbapenems, and Enterococcus spp. resistant to vancomycin. Results: Among patients with...

Healthcare-associated urinary tract infections in urology

José Medina-Polo, Kurt Georg Naber & Truls Erik Bjerklund Johansen
The purpose of the present review is to report the incidence and characteristics of healthcare-associated urinary tract infections (HAUTIs) in urology with their microbiological and resistance patterns. Urinary tract infections are the main type of healthcare-associated infection in patients hospitalized in a urology ward. Patients admitted to urology departments report a high prevalence of urinary tract catheterization, up to 75% during the hospitalization period, and up to 20% had a urinary catheter before admission. An...

Registration Year

  • 2021

Resource Types

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  • Hospital Universitario 12 De Octubre
  • Oslo University Hospital
  • Technical University of Munich
  • École Polytechnique Fédérale de Lausanne
  • Washington University Medical Center
  • Harvard University
  • University Hospital of Lausanne