2 Works

Teaching indicators to unravel the kinetic features of host–guest inclusion complexes

Amrutha Prabodh, Stephan Sinn, Laura Marie Grimm, Zsombor Miskolczy, Mónika Megyesi, Laszlo Biczok, Stefan Braese & Frank Biedermann
Three new, practically convenient methods are introduced for measuring kinetic parameters of supramolecular host–guest and protein–ligand complexes. Combined with thermodynamic data, this allows for an in-depth of the binding mechanism.

Simultaneous analyte indicator binding assay (SBA) for the monitoring of reversible host–guest complexation kinetics

Zsombor Miskolczy, Mónika Megyesi, Stephan Sinn, Frank Biedermann & Laszlo Biczok
Competitive binding of an indicator dye and an optically silent guest was exploited to develop a powerful method for the accurate determination of the kinetic and thermodynamic parameters of host–guest complex formation.

Registration Year

  • 2022

Resource Types

  • Dataset


  • Institute of Materials and Environmental Chemistry
  • Institute of Nanotechnology
  • Karlsruhe Institute of Technology