5 Works

A linkage-based genome assembly for the mosquito Aedes albopictus and identification of chromosomal regions affecting diapause

John Boyle, Peter Armbruster, Pasi Rastas, Xin Huang, Austin Garner, Indra Vythilingam & Peter Armbruster
The Asian tiger mosquito, Aedes albopictus, is an invasive vector mosquito of substantial public health concern. The large genome size (~1.19-1.28 Gb by cytofluorometric estimates), comprised of ~68% repetitive DNA sequences, has made it difficult to produce a high-quality genome assembly for this species. We constructed a high-density linkage map for Ae. albopictus based on 111,328 informative SNPs obtained by RNAseq. We then performed a linkage-map anchored reassembly of AalbF2, the genome assembly produced by...

Phylogenomic analysis of ultraconserved elements resolves the evolutionary and biogeographic history of Segmented Trapdoor Spiders

Xin Xu, Yong-Chao Su, Simon Y. W. Ho, MatjaĆŸ Kuntner, Hirotsugu Ono, Fengxiang Liu, Chia-Chen Chang, Natapot Warrit, Varat Sivayyapram, Khin Pyae Pyae Aung, Dinh Sac Pham, Y. Norma-Rashid & Daiqin Li
The segmented trapdoor spiders (Liphistiidae) are the sole surviving family of the suborder Mesothelae, which forms the sister lineage to all other living spiders. Liphistiids have retained a number of plesiomorphic traits and their present-day distribution is limited to East and Southeast Asia. Studying this group has the potential to shed light on the deep evolutionary history of spiders, but the phylogeny and divergence times of the family have not been resolved with confidence. We...

The impact of a pressure ulcer prevention educational program based on the health belief model for persons with spinal cord injury

Natiara Mohamad Hashim, Julia Patrick Engkasan & Nazirah Hasnan
Pre- and post- trial. To determine the changes of health belief levels after a pressure ulcer (PrU) prevention educational program based on the Health Belief Model (HBM) Department of Rehabilitation Medicine, University Medical Centre, Malaysia. This study was conducted between May 2016 and May 2018. We created a multidisciplinary structured PrU prevention education program based on the HBM, consisting of didactic lectures, open discussions and a practical session. The content of the program was based...

Rosmarinic acid exhibits broad anti-enterovirus A71 activity by inhibiting the interaction between the five-fold axis of capsid VP1 and cognate sulfated receptors

Chung-Fan Hsieh, Jia-Rong Jheng, Guan-Hua Lin, Yu-Li Chen, Jin-Yuan Ho, Chien-Jou Liu, Kuei-Yang Hsu, Yuan-Siao Chen, Yoke Fun Chan, Hui-Ming Yu, Pei-Wen Hsieh, Jyh-Haur Chern & Jim-Tong Horng
Enterovirus A71 (EV-A71), a positive-stranded RNA virus of the Picornaviridae family, may cause neurological complications or fatality in children. We examined specific factors responsible for this virulence using a chemical genetics approach. Known compounds from an anti-EV-A71 herbal medicine, Salvia miltiorrhiza (Danshen), were screened for anti-EV-A71. We identified a natural product, rosmarinic acid (RA), as a potential inhibitor of EV-A71 by cell-based antiviral assay and in vivo mouse model. Results also show that RA may...

The impact of a pressure ulcer prevention educational program based on the health belief model for persons with spinal cord injury

Natiara Mohamad Hashim, Julia Patrick Engkasan & Nazirah Hasnan
Pre- and post- trial. To determine the changes of health belief levels after a pressure ulcer (PrU) prevention educational program based on the Health Belief Model (HBM) Department of Rehabilitation Medicine, University Medical Centre, Malaysia. This study was conducted between May 2016 and May 2018. We created a multidisciplinary structured PrU prevention education program based on the HBM, consisting of didactic lectures, open discussions and a practical session. The content of the program was based...

Registration Year

  • 2021
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Affiliations

  • University of Malaya
    5
  • National University of Singapore
    1
  • Chulalongkorn University
    1
  • Georgetown University
    1
  • Vietnam Academy of Science and Technology
    1
  • University of Sydney
    1
  • University of Yangon
    1
  • Hubei University
    1
  • Kaohsiung Medical University
    1
  • National Institute of Biology
    1